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Direct letters to relatives at risk of hereditary cancer—a randomised trial on healthcare-assisted versus family-mediated risk disclosure

Observational studies suggest that direct contact from healthcare to at-risk relatives may increase genetic counselling (GC) uptake as compared to family-mediated risk disclosure, but randomised controlled trials (RCTs) are lacking. This study assessed whether the offer of direct letters to relatives at risk of hereditary breast and ovarian cancer (HBOC) or Lynch syndrome increases GC uptake compa

Risk of Diabetes Among Young Adults Born Preterm in Sweden

OBJECTIVE-Previous studies have suggested that preterm birth is associated with diabetes later in life. These studies have shown inconsistent results for late preterm births and have had various limitations, including the inability to evaluate diabetic outpatients or to estimate risk across the full range of gestational ages. Our objective was to determine whether preterm birth is associated with

Ischemic Stroke and Secondary Prevention in Clinical Practice A Cohort Study of 14 529 Patients in the Swedish Stroke Register

Background and Purpose-Secondary prevention is recommended after stroke, but adherence to guidelines is unknown. We studied the prescription of antiplatelet drugs, angiotensin-converting enzyme inhibitors, statins, and anticoagulant drugs and their relation to risk of death. Methods-Patients with first-ever ischemic stroke in 2005 were registered in the Swedish Stroke Register. Odds ratios, hazard

Treatment of humerus fractures in the elderly : A systematic review covering effectiveness, safety, economic aspects and evolution of practice

Objectives The objective of this Health Technology Assessment was to evaluate effectiveness, complications and cost-effectiveness of surgical or non-surgical treatment for proximal, diaphyseal or distal fractures of the humerus in elderly patients. Secondary objectives were to evaluate the intervention costs per treatment of proximal humerus fractures (PHF) and to investigate treatment traditions

Elevated circulating effector memory T cells but similar levels of regulatory T cells in patients with type 2 diabetes mellitus and cardiovascular disease

Type 2 diabetes mellitus is associated with an elevated risk of cardiovascular disease, but the mechanism through which diabetes contributes to cardiovascular disease development remains incompletely understood. In this study, we compared the association of circulating regulatory T cells, naïve T cells, effector memory T cells or central memory T cells with cardiovascular disease in patients with

Brain natriuretic peptide levels in middle aged subjects with normal left ventricular function in relation to mild-moderate COPD

Background: Levels of plasma brain natriuretic peptide (BNP) have been shown to be elevated in chronic obstructive pulmonary disease (COPD) especially in connection with cor pulmonale (CP) and the late stages of the disease. BNP is also raised in left sided heart failure which sometimes coincides with COPD. Whether BNP is elevated in subjects with mild-moderate stable COPD and normal left ventricu

Variations in the practice of molecular radiotherapy and implementation of dosimetry : results from a European survey

Background: Currently, the implementation of dosimetry in molecular radiotherapy (MRT) is not well investigated, and in view of the Council Directive (2013/59/Euratom), there is a need to understand the current availability of dosimetry-based MRT in clinical practice and research studies. The aim of this study was to assess the current practice of MRT and dosimetry across European countries. Metho

Half-lives of PFOS, PFHxS and PFOA after end of exposure to contaminated drinking water

BACKGROUND: Municipal drinking water contaminated with perfluorinated alkyl acids had been distributed to one-third of households in Ronneby, Sweden. The source was firefighting foam used in a nearby airfield since the mid-1980s. Clean water was provided from 16 December 2013.OBJECTIVE: To determine the rates of decline in serum perfluorohexane sulfonate (PFHxS), perfluorooctane sulfonate (PFOS) a

Effect of flecainide on atrial fibrillatory rate in a large animal model with induced atrial fibrillation

Background: Atrial fibrillatory cycle length has been considered one of the indices of atrial electrical remodelling during atrial fibrillation (AF), which can be assessed from surface ECG by computer-assisted calculation of atrial fibrillatory rate (AFR). Horses have been suggested as a bona fide model for AF studies since horses too, develop lone AF, however data on AF characteristics in horses

Association between serum levels of testosterone and biomarkers of subclinical atherosclerosis

Objective: To investigate the association between serum levels of testosterone and biomarkers of subclinical atherosclerosis based on data from 119 middle-aged men of the general population. Methods: Testosterone, Apolipoprotein A-1 (ApoA-1), Apolipoprotein B (ApoB), Apolipoprotein B-to-Apolipoprotein A-1 ratio (ApoB-to-ApoA-1), high-sensitive C-reactive protein (hsCRP), and fibrinogen levels were

The association between medical diagnosis and caregiver burden : a cross-sectional study of recipients of informal support and caregivers from the general population study ‘Good Aging in Skåne’, Sweden

Background: Different kinds of chronic diseases might imply different dimensions of caregiver burden, not previously described among the caregivers to recipients from the general elder population. Aim: The main objective was to examine differences in burden between the 343 caregivers to persons with different diagnoses. Methods: A group of elderly recipients of informal care (n = 343) from the gen

Long-term prediction of prostate cancer diagnosis and death using PSA and obesity related anthropometrics at early middle age : Data from the malmö preventive project

Objectives: To evaluate whether anthropometric parameters add to PSA measurements in middle-aged men for risk assessment of prostate cancer (PCa) diagnosis and death. Results: After adjusting for PSA, both BMI and weight were significantly associated with an increased risk of PCa death with the odds of a death corresponding to a 10 kg/m2 or 10 kg increase being 1.58 (95% CI 1.10, 2.28; p = 0.013)

Side-chain engineering by thymine groups enables hydrogen bond in P-type donor-acceptor polymers with enhanced optoelectronic properties

Realizing ordered structures at the molecular level is a key approach to increase the charge mobility of organic semiconductors. However, the typical solution-based methods employed for the processing make the achievement of well-organized organic nanostructures difficult with the favored formation of disordered assemblies. To realize well-ordered thin films, one needs to design conjugated materia

Personalized breast cancer screening with selective addition of digital breast tomosynthesis through artificial intelligence

PURPOSE: Breast cancer screening is predominantly performed using digital mammography (DM), but digital breast tomosynthesis (DBT) has higher sensitivity. DBT demands more resources than DM, and it might be more feasible to reserve DBT for women with a clear benefit from the technique. We explore if artificial intelligence (AI) can select women who would benefit from DBT imaging.APPROACH: We used

Effect of Weight Maintenance on Symptoms of Knee Osteoarthritis in Obese Patients: A Twelve-Month Randomized Controlled Trial 1

Objective. To compare results of obese patients with knee osteoarthritis (OA) who, after an intensive weight loss regimen, received 1 year of either dietary support (D), a knee-exercise program (E), or "no attention" (C; control group). Methods. We conducted a randomized, 2-phase, parallel-group trial. A total of 192 obese participants with knee OA were enrolled; the mean age was 62.5 years and 81

North-south gradients in plasma concentrations of B-vitamins and other components of one-carbon metabolism in Western Europe: results from the European Prospective Investigation into Cancer and Nutrition (EPIC) Study

Different lifestyle patterns across Europe may influence plasma concentrations of B-vitamins and one-carbon metabolites and their relation to chronic disease. Comparison of published data on one-carbon metabolites in Western European regions is difficult due to differences in sampling procedures and analytical methods between studies. The present study aimed, to compare plasma concentrations of on

Utvärdering Samtida Internationell Scenkonst VT 2024

Systemförvaltaren testar Samtida internationell scenkonst VT 2024 Antal svar: 4 Motsvarade kursen dina förväntningar? Motsvarade kursen dina förväntningar? Ja Både ja och nej, på många sätt överträffade den mina förväntningar. Det var helt fantastiskt bra upplägg och dialog med lärare och sedan klart alla dessa internationella kontakter som ställde upp och gav oss verkliga redogörelser! Å andra si

https://www.thm.lu.se/sites/thm.lu.se/files/2024-10/Utv%C3%A4rdering%20Samtida%20internationell%20scenkonst%20VT%202024.pdf - 2026-05-23

Letter-of-reference-template

Reference letter template for SAYP 2021 The Swedish Institute (SI) Academy for Young Professionals (SAYP) Enclosure to your application for participation in the SAYP 2021 LETTER OF REFERENCE FORM - INSTRUCTIONS Examples of who can be your reference person · Supervisor · Employer/head/director · Tutor/mentor Examples of who cannot be referred to and used as reference person · Family members/relativ

https://www.lunduniversity.lu.se/sites/www.lunduniversity.lu.se/files/2021-02/letter-of-reference-template.docx - 2026-05-23

Letter Of Reference 2022-SAYP

Reference letter template for SAYP 2021 The Swedish Institute (SI) Academy for Young Professionals (SAYP) Enclosure to your application for participation in the SAYP 2022 LETTER OF REFERENCE FORM - INSTRUCTIONS Examples of who can be your reference person · Supervisor · Employer/head/director · Tutor/mentor Examples of who cannot be referred to and used as reference person · Family members/relativ

https://www.lunduniversity.lu.se/sites/www.lunduniversity.lu.se/files/2022-03/Letter%20of%20Reference%202022-SAYP.docx - 2026-05-23