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Mutations in the low-density lipoprotein receptor gene in Swedish familial hypercholesterolaemia patients: clinical expression and treatment response

BACKGROUND: Familial hypercholesterolaemia, an autosomal co-dominant disorder caused by defects in the low-density lipoprotein receptor gene, is strongly associated with premature development of cardiovascular disease. METHODS: In this study, we have applied a gene screening method in a population of familial hypercholesterolaemia patients in order to describe the genetic background of the disease

Wenlock bentonites in Lithuania and correlation with bentonites from sections in Estonia, Sweden and Norway

Seven Wenlock bentonite beds from four drill cores in Lithuania with sufficient thickness for sampling were analysed by XRD and XRF. The sanidine composition of bentonites combined with graptolite biozonation of the host rock were used for correlations. Two of the studied bentonite samples at the antennularius/flexilis biozone boundary can be confidently correlated between two Lithuanian sections.