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The results presented in this thesis demonstrate that the magnetic relaxation dispersion (MRD) technique can provide information of relevance to protein biophysics, magnetic resonance imaging and cell biology. By immobilizing proteins with covalent cross-links, intermittent protein dynamics on the previously inaccessible ns-µs time scale could be probed with MRD via the exchange of water molecule
STUDY OBJECTIVE: To assess whether in an urban population stage at breast cancer diagnosis is related to area of living and to what extent intra-urban differences in breast cancer mortality are related to incidence respectively stage at diagnosis. DESIGN: National registries were used to identify cases. Mortality in 17 residential areas was studied in relation to incidence and stage distribution u
Popular Abstract in English Every level of human existence is affected by forced migration. It affects the central aspects of our outer and inner life. However, scientific research focused on the inner life of forced migrants, in particular the one regarding the impacts of forced migration on the most significant values that we hold in life, is often marginalized in forced migration studies. In anUntil recently studies regarding the pathological aspects of refugee experiences have led the psychology field of forced migration, giving little space to positive factors like the resilience and well-being of individuals faced with these adversities. This doctoral thesis emphasizes good health rather than disease and aims at deepening the understanding of resilience and health as opposed to the d
daptive responsive environments that encourage interaction for children with severe disabilities offer a distinct potential for play and learning in rehabilitation. Physical training and therapy for these children is often enduring, tedious, and boring through repetition - and this is often the case for both the child and the facilitator/therapist. Despite this, little is yet known about how the u
Isocyanates may cause occupational asthma, rhinitis, and hypersensitivity pneumonitis. However, the mechanisms behind initiation of the disorders and the relations between exposure and effect are insufficiently elucidated. Means to biomonitor exposure and risk would be valuable. A case, exposed to heated polyurethane, displayed metabolites of 4,4'-dipheylmethane diisocyanate in blood and urine, an
This paper studies family commitment among fast-track professionals and explores how continued childbearing and union stability vary among high-achieving men and women. The focus is on three particular fast-track professional groups (e.g., lawyers, medical doctors and Ph.D.s), that face quite different career structures and work environments that may affect family life. The determinants of having
The accuracy of dose calculations for various aspects of a treatment planning system (TPS) using an energy fluence beam modelling has been evaluated. The investigated TPS uses a beam model, which separates the energy fluence into a number of sources in the treatment head. The energy fluence components are transported towards the patient and, together with the scatter generated in the patient, yiel
The well-institutionalised notion of audits put forth that information subjected to independent examination by third parties potentially contribute to better quality information for decision making (towards more sustainable companies?). The presence of different assurance providers offering a myriad of services in the name of “sustainability assurance” led to concerns about their quality and compa
Objective: The primary aim of this study was to investigate whether there was any difference in scores of the Cleft Hearing, Appearance and Speech Questionnaire (CHASQ) between patients with cleft lip and/or cleft palate (CL/P) and a control population. The second aim was to compare CL/P and control population scores in this study with a British norm CL/P population. Design: Single-site, cross-sec
Mortality differentials by socioeconomic status (SES) are among the most pervasive facts of contemporary demography. However, while the mortality gradient by income, class and education is well-established for the period after 1970, evidence regarding the origins of the gradient is still scarce. The aim of this thesis is to explore the development of SES differences in all-cause and cause-specific
The transport of fallout-90Sr has been investigated in the food-chain: Lichen-reindeer-man during 1961-1969. The maximum levels which occurred in lichen during 1963-1965 were about 13 nCi/kg dry wt. The90Sr-level in the lichen-carpet decreased to about 5 nCi/kg dry wt. in 1967-1969. The effective half-time of 90Sr in the lichen-carpet was estimated to be 2.5 ± 0.8 a. The vertical distribution of90
Although there is extensive research indicating the vital role of functional emotion regulation (ER) in healthy psychological development, such research has neglected examination of adolescents. One potential reason for this neglect is the lack of valid ER instruments developed specifically for adolescents. Further, the available ER instruments for adolescents usually require elaborate forms of co
Milk that does not coagulate after rennet addition, also called noncoagulating (NC) milk, is unwanted in cheese production due to prolonged processing time. Amounts of whey and casein proteins, genetic variants, as well as posttranslational modifications (PTM) of proteins are all contributing factors in rennet-induced coagulation of milk. In this study, we conducted a wide-ranging investigation of
