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Background: Waist circumference (WC) is a simple and reliable measure of fat distribution that may add to the prediction of type 2 diabetes (T2D), but previous studies have been too small to reliably quantify the relative and absolute risk of future diabetes by WC at different levels of body mass index (BMI). Methods and Findings: The prospective InterAct case-cohort study was conducted in 26 cent

Objective: The aim of this study was to assess the mortality in hip fracture patients with regard to use of fall-risk-increasing drugs (FRIDs), by comparing survival in exposed and nonexposed individuals. Design: This was a general population-based cohort study. Settings: Data on hip fracture patients were retrieved from three national databases. Participants: All hip fracture patients aged 60 yea

Species-based ecological indices, such as Ellenberg indicators, reflect plant habitat preferences and can be used to describe local environment conditions. One disadvantage of using vegetation data as a substitute for environmental data is the fact that extensive floristic sampling can usually only be carried out at a plot scale within limited geographical areas. Remotely sensed data have the pote

Clinical education is a significant part of nursing education on all levels of education. A lot of effort is made by educational providers to prepare the students for their clinical placement (Levett-Jones et al., 2015). At best, this is a shared enterprise, involving representatives from the profession in creating a useful clinical placement for the students. However, the strain on clinical nurse

*Summary: The bacterium Escherichia coli is a common host organism for recombinant protein production. A problem encountered is the accumulation of the by-product acetate, which tends to reduce growth and protein production (1). Formation of acetate can be avoided by a proper substrate feeding strategy, but most strategies require considerable process knowledge to work well. The main problem is th

The interest in modelling, analysis and optimisation of supply chain structures has increased in the last decade. Among the reasons are globalisation, a general speed-up of the rate of change in the business environment, the trend towards more outsourcing of activities, and the rapid development in IT. This development has caused more and more people to realise the benefits of supply chain managem

Background: A growing body of evidence shows that prenatal exposure to phthalates affects child development. Since many phthalates have been shown to alter endocrine signaling, they may influence reproductive development, neurodevelopment, and child behavior. Indeed, a few studies reported associations between prenatal phthalate exposure and gender-specific play behavior. However, evidence for thi

Background: The migratory process in birds consists of alternating periods of flight and fueling. Individuals of some populations make few flights and long stopovers, while others make multiple flights between short stopovers. Shorebirds are known for executing marathon flights (jumps), but most populations studied are long distance migrants, often crossing major barriers and thus forced to make l

A sports-related concussion (SRC) is most commonly sustained in contact sports, and is defined as a mild traumatic brain injury. An exercise-induced elevation of core body temperature is associated with increased brain temperature that may accelerate secondary injury processes following SRC, and exacerbate the brain injury. In a recent pilot study, acute head-neck cooling of 29 concussed ice hocke

Background/Aim: Signs of hypoxic ischaemic encephalopathy (HIE) on head computed tomography (CT) predicts poor neurological outcome after cardiac arrest. We explore whether levels of brain injury markers in blood could predict the likelihood of HIE on CT. Methods: Retrospective analysis of CT performed at 24–168 h post cardiac arrest on clinical indication within the Target Temperature Management

The relation between worship and gender is a hot topic in the Catholic Church. In recent decades, the debate has mostly been about breaking with patriarchal and male dominated liturgical forms and traditions. Yet, in Catholic traditionalist Catholic liturgy, due to the reform after the Second Vatican council, is considered to have lost much of its former masculine character. In my article, I addre

Background Neighborhood deprivation has been found associated with both type 2 diabetes and lung cancer. The aim of this study was to examine the potential association between neighborhood deprivation and lung cancer incidence or mortality in individuals diagnosed with type 2 diabetes. The results may identify a new risk or prognostic factor for lung cancer in this important subgroup and help deve

Background: C-type natriuretic peptide (CNP) is a known target for promoting growth and has been implicated as a therapeutic opportunity for the prevention and treatment of cardiovascular disease (CVD). This study aimed to explore the effect of CNP on CVD risk using the Mendelian randomization (MR) framework. Methods: Instrumental variables mimicking the effects of pharmacological intervention on

BackgroundMuch longitudinal research has been carried out on non-suicidal self-injury (NSSI) during the last decades, but there still is a lack of studies of the individual developmental pathways of NSSI from adolescence into young adulthood. The aim of the present study was to investigate individual developmental pathways of repetitive non-suicidal self-injury (repNSSI) from adolescence into youn

BACKGROUND: Oncological outcome after radical radiotherapy (RRT) combined with neoadjuvant and adjuvant androgen suppression therapy (AST) may differ according to type of AST. The aim of this nationwide register-based study was to investigate risk of prostate cancer (Pca) death after different neoadjuvant and adjuvant ASTs; (i) bicalutamide, (ii) gonadotropin-releasing hormone agonists (GnRH) or (

BackgroundOrthostatic hypotension (OH) occurs when blood pressure regulation fails. The underlying molecular mechanism of OH remain largely unexplored. Endostatin is a biologically active molecule cleaved by matrix metalloproteinases, elastases and cathepsins from collagen XVIII in the extracellular matrix and inhibits angiogenesis. Circulating levels of endostatin have been proposed to be involve