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Background: Both chronic pain and depressive and/or anxiety symptoms are associated with negative impacts on daily living, including interference and lack of life control. However, little is known about how pain and psychological distress affect these impacts. Aim: The first aim was to assess how pain intensity, psychological distress, and social support interact with interference and lack of life
This thesis emanates from the discursive gap between a medical discourse andexperience-driven knowledges in mental health aspects of hormonal contraceptives.The tensions and fractures between a medical discourse focusing on contraceptiveeffectiveness and largely refuting any significant adverse outcomes, and experiencebasednarratives of commonplace detrimental, or at least unwelcome and unpleasant
BACKGROUND: A global trend is to move rehabilitation closer to people's neighborhoods and homes. Still, little attention has been given to how the built environment outside the hospital setting might impact rehabilitation and recovery for stroke survivors.OBJECTIVE: The overarching objective of this project is to develop conceptual models of built environments that support stroke rehabilitation an
Background: Snacking is a common diet behaviour which accounts for a large proportion of daily energy intake, making it a key determinant of diet quality. However, the relationship between snacking frequency, quality and timing with cardiometabolic health remains unclear. Design: Demography, diet, health (fasting and postprandial cardiometabolic blood and anthropometrics markers) and stool metagen
Background: Women with adverse pregnancy outcomes may have higher subsequent risk of chronic kidney disease, but the long-term independent risks and potential causality are unclear. Objective: This study aimed to determine long-term risks of chronic kidney disease associated with 5 major adverse pregnancy outcomes in a large population-based cohort, and to assess for familial confounding using co-
Direct oral anticoagulants (DOACs) used in nonvalvular atrial fibrillation (NVAF) are dose-reduced in elderly and patients with impaired renal function. Only reduced dose dabigatran is concluded as having similar stroke risk reduction and lower risk of major bleeding than warfarin in the pivotal studies. In clinical practice, reduced dose is prescribed more often than expected making this an impor
Objective: Accurate imaging biomarkers that indicate disease progression at an early stage are highly important to enable timely mitigation of symptoms in progressive lung disease. In this context, reproducible experimental models and readouts are key. Here, we aim to show reproducibility of a lung injury rat model, by inducing disease and assessing disease progression by multi-modal non-invasive
BackgroundSelenoprotein P (SELENOP) is a transporter for selenium and has been shown to protect selenium status maintenance in brain against deficiency, supporting neuronal development, neurogenesis and neurocognitive function. Selenium deficiency has previously been associated with cognitive impairment in various populations, but no studies have been carried out in subjects with heart failure (HF
Cardiometabolic conditions such as obesity and type 2 diabetes (T2D) are among the first causes of death globally, and the number of people affected is rapidly increasing. Both conditions are intricately connected and are associated with many life-threatening cardiovascular disease (CVD). However, both obesity and T2D are highly heterogeneous, such that not all individuals with these conditions de
Full text linksBMC Public Health. 2026 Apr 17;26(1):1273.doi: 10.1186/s12889-026-27378-1.Individual and environmental determinants of body mass index trajectories: results from a longitudinal study in Southern SwedenPauline Rebouillat 1 , Kristoffer Mattisson 2 , Giedre Gefenaite 3 , Per-Olof Östergren 4 , Peter M Nilsson 5 6 , Jonas Björk 2 7Affiliations PMID: 41998602 PMCID: PMC1309
Background: Obesity and type 2 diabetes (T2DM) are considered risk factors for complications following total hip arthroplasty (THA). How these risk factors separately or in combination influence the risk of reoperation due to periprosthetic joint infection (PJI) or all-cause reoperation is not fully known. We sought to investigate the 2-year risk of reoperation following THA due to osteoarthritis
This thesis consists of three self-contained papers that examine how information and ideologies serve as coordinating forces during episodes of political and social transformation.The first paper studies how shifts in public sentiment can trigger mass mobilization, using the Finnish Civil War of 1918 as a natural experiment. I show that the abrupt abolition of Russian imperial censorship in 1917 p
BACKGROUND: Spinal cord injury (SCI) may, and often does, profoundly reshape daily life, altering physical abilities, social roles, and personal identities. While assistive technologies, including assistive robotics, are often framed as solutions to re-establish independence, their adoption is shaped by practical, emotional, and social considerations as well as functional qualities. Individuals wi
Emerging evidence suggests that bidirectional lung–kidney crosstalk may influence outcomes, but this has not been systematically evaluated in unselected emergency department populations. We therefore examined the association between peripheral oxygen saturation (SpO₂), estimated glomerular filtration rate (eGFR), and 30‑day mortality, and tested whether the prognostic association of oxygenation wi
Increasing CO₂ emission is considered as the main reason for global warming in the world. One of the reasons for producing CO₂ is using of fossil-based materials in the construction projects. This study intends to assess the using bio-based materials instead of fossil-based materials for the thermal insulation layer of the external walls and roofs. Another focus of this project is using green conc
BACKGROUND: Weight-adjusted-waist index (WWI) is an anthropometric index reflecting fat mass and muscle mass, both of which are important factors influencing insulin resistance and inflammation.OBJECTIVES: We aimed to examine the associations of WWI with all-cause, cardiovascular, and noncardiovascular mortality among individuals with type 2 diabetes (T2D) and further investigate whether insulin r
Background and ObjectivesSpinocerebellar ataxias (SCAs) and other neurodegenerative cerebellar ataxias (N-SCAs) involve alterations in cerebellar structure and function, affecting motor control and sensorimotor integration but also cognitive functions such as visuospatial processing. The cerebellum is essential for sensorimotor functions, and it contributes to cognition. The study aims to assess s
INTRODUCTION: Since the last two decades, there has been a dramatic rise in caesarean sections (CS) throughout the world. This increase has been seen even in Europe, where rates vary significantly from 17% in Northern Europe to 56% in the South. Although, CS can be a lifesaving intervention when medically necessary, non-essential CS are associated with short- and long-term complications for both t
