Filtyp
Industrial redevelopment has become an increasingly pressing urban challenge as cities expand and central industrial areas are drawn into the evolving urban fabric. While regeneration projects often succeed in giving former industrial sites new roles, the preservation of the industrial legacy is frequently reduced due to the conflicting demands between industrial and central urban functions. What
We investigate whether the eye parameter of bumblebees—a visual trait measuring the tradeoff between light sensitivity and visual resolution—is associated with: (i) local habitats, (ii) forest cover at the landscape scale (1 km radius), and (iii) the shade tolerance of the plants they forage on. The association of bumblebee species with local habitat and forest cover at the landscape scale was ana
Perturbed secretion of insulin and other pancreatic islet hormones is the main cause of type 2 diabetes (T2D). The islets harbor five cell types that are potentially altered differently by T2D. Whole-islet transcriptomics and single-cell RNA-sequencing (scRNAseq) studies have revealed differentially expressed genes without reaching consensus. Here, we demonstrate that further insights into T2D dis
CONTEXT: Statin use is associated with increased risk of type 2 diabetes and mild hyperglycemia. The underlying mechanisms are not well studied and the effect of statin treatment on GLP-1 secretion or production are unknown.OBJECTIVE: To assess the effects of rosuvastatin on GLP-1 secretion and production.METHODS: We performed association studies in the Malmö Diet and Cancer study cardiovascular c
Purpose: To investigate how the nation brand and country-of-origin of China jointly influence the European consumers’ perceptions towards Chinese smartphone brands. The reputation of Chinese smartphone brands in Europe is shaped by European consumers' concerns about China's national image over their global success and technological advancements. Hence, this study focuses on how these perce
Background and study aims Surgical resection is standard treatment of T2 rectal cancer due to risk of concomitant lymph node metastases (LNM). Local resection could potentially be an alternative to surgical treatment in a subgroup of patients with low risk of LNM. The aim of this study was to identify clinical and histopathological risk factors of LNM in T2 rectal cancer. Patients and methods This
Co-speech head and eyebrow gestures often align with pitch accents in spoken language production, thereby likely instantiating what we could refer to as multimodal prominence. Indeed, when speech is perceived audio-visually, controlled experimental studies have shown that both pitch accents and head and eyebrow gestures, when independently manipulated, have sizable effects on perceived prominence.
Peatland trees are valuable archives of paleoclimatic information; however, gaps persist in understanding the relationships between tree growth, peatland hydrology, and hydroclimate variables. While previous research in peatlands has mainly focused on tree-ring widths (TRW), yielding inconclusive results, the potential of stable carbon (δ13C) and oxygen (δ18O) isotopes in tree rings remains unexpl
Objective: Both attention-deficit/hyperactivity disorder (ADHD) and neighborhood deprivation have been previously associated with an increased risk of type 2 diabetes (T2D). However, the potential association between neighborhood deprivation and T2D in ADHD patients remains underexplored. Our aim was to study the potential effect of neighborhood deprivation on incident T2D in patients with ADHD. M
In the centre of Malmö, Caroli Church stands in quiet suspension—its doors closed, its future uncertain. Neither abandoned nor alive, it occupies a space between preservation and possibility. In a society where churches are increasingly disconnected from their original function, the question lingers: what becomes of the sacred when it no longer serves the ritual? And who, ultimately, decides what
Evidence on the predictive ability of risk assessment models for event-free survival (EFS) in patients with pulmonary arterial hypertension is scarce. We aimed to investigate the relationship between risk status at 6 months after diagnosis (6 M) and EFS, by three risk models: Multicomponent Improvement (MCI), ESC/ERS 4-Strata Risk (4SR), and noninvasive French PH Registry Score (FRS). Data collect
For exploring forest performance in the future, dynamic vegetation models are important tools. Tree mortality is a crucial process in these models, but explicit representations of major agents of mortality have often been relatively underdeveloped. In needle-leaved forest in the temperate and boreal zones, bark beetles are often important for the mortality pattern. The European spruce bark beetle
Diabetic kidney disease (DKD) is a health burden that lacks specific and early diagnostic biomarkers. For their discovery, we sequenced urinary extracellular vesicle miRNAs in a type 1 diabetes cohort of males with and without DKD. The results were replicated by sequencing or qPCR in two independent cohorts and six published datasets, including type 1 and 2 diabetes, and both sexes. We also valida
Introduction Lynch syndrome (LS) carriers have a 20-46% lifetime risk of colorectal cancer (CRC) due to mismatch repair gene variants. Mesalamine (5-ASA, 5-aminosalicylic acid), used safely in patients with ulcerative colitis, may reduce CRC risk in LS by decreasing microsatellite instability, a key driver of LS-related cancer. This study evaluates 5-ASA's efficacy as a tolerable chemopreventive d
