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Antennal detection and central nervous integration of behaviourally relevant odours in scarab beetles (Coleoptera: Scarabaeidae) was investigated, using the two Japanese scarabs Anomala cuprea and Phyllopertha diversa (Rutelinae), and the Central African fruit chafer Pachnoda marginata (Cetoniinae) as model species. Electrophysiological single cell recordings in A. cuprea and P. diversa character
When a person becomes critically ill, injured and/or undergoes major surgery and requires intensive care, a complex dilemma can arise. The condition of the illness, the specific caring situation and the environment lead to significant changes and effects in the senses and perceptional abilities. Under these conditions some patients can develop symptoms of the Intensive Care Unit syndrome/delirium.
Calcium homeostasis after thyroid surgery was studied during the immediate postoperative period and after one year. One day after hemithyroidectomy ionised calcium decreased whereas basal PTH did not change. EDTA stimulated maximal and total PTH secretion and set-point decreased on postoperative day 1 and normalised on day 7. One year after hemithyroidectomy (n=10) total calcium and 1.25(OH)2D3 de
The complement system is critically involved in defence against bacterial infection. C2 deficiency is, apart from mannan-binding lectin (MBL) deficiency, the most common homozygous complement deficiency among Caucasians. The classical pathway of complement activation is not functional in C2 deficiency and the condition is associated with invasive infections caused by the encapsulated bacteria Stre
Some aspects on the use of light for tissue characterization and treatment of malignant tumours are discussed within this thesis. The work presented aims at improving optical techniques for tissue characterization, especially to detect malignant and pre-malignant lesions. A knowledge on the interaction between light and tissue is of utmost importance to understand and improve the various technique
The anatomy, function and plasticity of the primary olfactory centre, the antennal lobe (AL), of the desert locust Schistocerca gregaria was investigated using a number of neuroanatomical and neurophysiological methods. Anatomical characterisation of the AL in a number of orthopteran species made it possible to deduce a model concerning the evolution of microglomeruli. These neuropil structures, c
This thesis deals with single-electron tunneling in transistor-like devices in which the central electrode is either a metal nanoparticle (possibly ferromagnetic) or a molecular magnet. The investigated systems split into two different categories, depending on the size of the central island. The smaller islands, such as ultrasmall magnetic metal nanoparticles and Mn12 molecular magnets, are studie
This thesis analyses the development of ethics committees from a sociology of law perspective and a social steerage perspective ("social control"). The main question is: Why are ethics committees established? Institutionalised ethics committee is a rather new phenomenon, which has become widely spread in the last 20 years. The study points out the public ethical debate since the 1980s as a major e
Voices from within the victim movement express a need for morality to have fixed boundaries between good and evil, right and wrong. However, such a morality is not always easy to define and uphold. It is thought important to consider the victims particular experiences, through another logic and morality than the strictly legally defined. This dissertation studies victim support as a moral definiti
The aims of this thesis were to identify microRNAs (miRNAs) with prostate cancer prognostic and diagnostic potential, to discover miRNAs with therapeutic capacity against prostate cancer, and to investigate if prostate specific antigen (PSA) is miRNA regulated. Prostate cancer is a globally spread disease with low mortality, but some patients develop an aggressive lethal form of prostate cancer w
This thesis describes structural and functional studies of alpha-1-microglobulin (a1m), a 26 kDa plasma and tissue protein that is evolutionarily well-conserved and belongs to the lipocalin superfamily. The lipocalins are polypeptides of 160-190-amino acids that are folded into an 8-stranded beta-barrel forming a pocket with a hydrophobic interior. a1m carries heterogeneous yellow-brown chromophor
Galectins are small soluble proteins defined by a conserved sequence motif that forms a defining β-galactoside binding site shared among galectins; adjacent binding sites give each galectin a unique fine specificity for a specific subset of galactose containing glycans. A wealth of data now suggests important roles of galectins in both cancer and inflammation. The aim of this project is to get a c
Bärighetsmätningar är avgörande för att bedöma vägars kapacitet att hantera ökande trafikbelastningar. Enligt Trafikverket förväntas en ökning av personbilar med 27%, bussar med 17% och godstransporter med 46% fram till år 2040. Denna prognostiserade tillväxt leder till ökat vägslitage vilket i sin tur kräver mer omfattande underhåll och komplexare åtgärder i högtrafikerade områden. Traditionellt
The continual increase in incidence of cancer has created an urgent need for improved methods for diagnosis, prognosis and/or treatment. In this context, the field of biomarker research has expanded immensely during the last few years. This thesis, based on four original papers, revolves around protein biomarker discovery in cancer. For this purpose, an in-house design recombinant antibody microar
This thesis presents the work on the design of, construction of, and finally observations with, an experimental setup comprising a small telescope equipped with adaptive optics. The facility has been assembled at Lund Observatory, where also observations on the sky have been made. The aim of this project was to gain hands-on knowledge in the development of a real adaptive optics system and eventua
The events are described in the languages used at each event. Skadeståndsansvar för juridisk rådgivning i ljuset av NJA 2022 s. 354 Måndagen 5 december 2022 kl. 16.00 - 18.00 Pufendorfsalen, Juridicum & Online (Zoom) Rättsfallet NJA 2022 s. 354 aktualiserar flera intressanta avtals- och skadeståndsrättsliga frågor i kontexten av juridisk rådgivning. Seminariet diskuterar vilka skyldigheter advokat
https://www.aclu.lu.se/en/events/past-events/2022 - 2025-11-23
Preclinical and 7T publications 2017Wasserstrom S, Morén B, Stenkula KG. Total Internal Reflection Fluorescence Microscopy to Study GLUT4 Trafficking. Methods Mol Biol. (2018) 1713:151-159. Published online 08 December 2017.Horstmann P.F., Raina D.B. , Isaksson H., Hettwer W., Lidgren L., PetersenM.M., Tägil M. Composite Biomaterial as a Carrier for Bone-Active Substances for Metaphyseal Tibial Bo
https://www.astro.lu.se/meridian-s03e01 - 2025-11-23
https://www.centralasianlaw.lu.se/teams - 2025-11-23
