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This doctoral thesis explored three broad aspects of preschoolers’ social competence: prosocial behavior, aggression, and social cognition. The longitudinal study followed forty-four children (initially 22-40 months), who were observed in natural peer interactions at their daycare centers during a two-month period in each of three con-secutive years. In addition, social-cognitive data were gathere
Secretory leukocyte protease inhibitor is a 11.7 kDa acid stable serine protease inhibitor. SLPI has been shown to be the dominant protease inhibitor in bronchial secretions and has been used in treatment of pulmonary emphysema. In ulcerative colitis faecal extracts has been shown to contain an abundance of free proteolytic activity, mainly leukocytic and pancreatic proteases. SLPI is a strong inh
Microdialysis was used to monitor local concentrations of energy metabolites in different organs, and to study the pharmacokinetics of morphine over the blood-brain barrier in intact and injured brain tissue in conditions treated in the Intensive Care Unit. After major abdominal or thoracoabdominal surgery, postoperative thoracic epidural analgesia resulted in higher glycerol concentrations in th
Whistle-blowing can serve as a powerful mechanism helping policy-makers and other stakeholders recognize ethical misconduct and other types of wrongdoing in autonomous public agencies. This mechanism is of particular importance in major public sector reforms, such as agency mergers, when it may be difficult to secure continuity in the quality of organizational processes. Yet, we know little of wha
This investigation comprises five studies of factors determining adults' interpretations of a picture (Threat), drawn to represent sexual abuse of a child. The sexes of the two persons in the picture were on purpose drawn ambiguously. In Study I, the Threat picture was interpreted by 515 undergraduates in three experiments, all resulting in the same four interpretation categories, and similar freq
A new Regulation on nutrition and health claims came into force in 2007 with implementation during a three-year period and will harmonise this area within the European Community. It makes provision for health claims on foods, including reduction of disease risk claims, and thus recognises the importance of food and nutrition for health. Member states have provided suggestions for claims regarding
This thesis is an archaeological study of a small region in northern Latium and the diachronical relationship between a nucleated settlement and its rural landscape. The work has a twofold basis: a review of earlier research concerning the settlement Luni sul Mignone in the light of more recent research, and a survey conducted by the present author of the territory of Luni. This survey and its res
We have found that a set of group A streptococcal strains, primarily associated with skin infections, express surface-associated M proteins that bind plasminogen and plasmin with high affinity. The binding is mediated by a common 13 amino acid internal repeated sequence located in the NH2-terminal surface-exposed portion of these M proteins. It could be demonstrated that plasminogen, absorbed by t
In the present study, L-tryptophan (TRP)-related disturbances in the brain in experimental hepatic encephalopathy (HE) were investigated. The endogenous NMDA-receptor agonist and L-TRP metabolite quinolinic acid (QUIN) has been suggested to be involved in the pathogenesis of HE. We were, however, unable to detect any increases in QUIN levels in rats subjected to a chronic portacaval shunt (PCS) ei
The aim of this study was to evaluate new MR techniques permitting qualitative and quantitative analysis of cardiac function and measurement of velocity and flow, and later on contrast-enhanced MR angiography, techniques largely unexplored in children with CHD. Infants with tetralogy of Fallot and pulmonary atresia with ventricular septal defect were examined pre-operatively. MRI was found to be a
During the 1980s and the 1990s several researchers have described new organisational features and a new organisational form in multinational enterprises, linked to a variety of theoretical approaches. Can the new organisational features be analysed from a consistent theoretical basis, and can, hereby, a new organisational form be distinguished from earlier forms? The purpose of this dissertation i
“The death of distance” has become the battle cry of a modern generation of managers, policy makers and scientists who embrace the new globalized economy and its promise of frictionless exchange across the world. While highly influential, this view does not, however, stand unchallenged. Over the last 15 years, there has been a growing interest in the geographical clustering of industry. Well-known
Cadastral Systems have developed during the latest decades, impelled by improved information technology. Cadastral projects have become more strategic in a development perspective, with expected long-term returns in economic growth.
An improvement of an existent information system requires an understanding of the basis of the current model, its coverage and the processes of change. The l
The administration’s legitimacy of the constitutional democracy consist in laws being applied in accordance with the principles which are their foundation. Care about the elderly is the municipals’ responsibility, and this task is regulated in the law of social services and the law of health and healthcare. The legislation grant individual elderly the right to a standard of living that in the law
The main aim of the thesis was to study different aspects of the therapeutic relationship in general psychiatric care, within various routine psychiatric settings with a variety of diagnostic patient groups and different staff groups. The first study investigated the patients' opinion on what constituted good psychiatric care. One outpatient and one inpatient sample were interviewed. The main resu
