Sökresultat

At least one of ten patients with ovarian cancer is estimated to develop their tumor because of heredity with the breast and ovarian cancer syndrome due to mutations in the BRCA1 and BRCA2 genes and hereditary nonpolyposis colorectal cancer (HNPCC) being the major genetic causes. Cancer at young age is a hallmark of heredity, and ovarian cancers associated with HNPCC have been demonstrated to deve

If present in large numbers, as during migration, herbivorous waterfowlmay reduce the amount of submerged vegetation. Because the vegetation is a keyfactor in shallow eutrophic lakes, removal of the green biomass can be expectedto affect also other biota that depend on the vegetation. We conducted anexperiment to determine how the abundance of chironomids andPisidium sp. were affected by intense f

1. Species richness is influenced by local habitat features and large-scale climatic gradients. Usually, both influences are studied in isolation because of the divergent spatial scales at which they occur. Here, we compared the influence of large-scale climate and local habitat type on European ants using a continent-wide, standardised sampling programme. 2. We investigated species richness and a

Severely deficient activity of the von Willebrand Factor (VWF) cleaving metalloprotease,ADAMTS 13, is associated with thrombotic thrombocytopenic purpura (TTP). The mutation spectrum ofADAMTS 13 is rather heterogeneous, and numerous mutations spread across the gene have been described in association with congenital TTP. The 4143insA mutation is unusual with respect to its geographic concentration.

BACKGROUND: The clinically important Kidd (JK) blood group antigens are carried by the urea transporter in red cells. The rare Jk(a-b-) phenotype can be caused by homozygosity at the JK locus for a silent allele, JK: This phenotype has been recorded in many ethnic groups, but it is most abundant among people originating from the Polynesian Islands and Finland. The molecular basis for Jk(a-b-) is u

Objective Recent studies suggest an increased prevalence of obstetric complications in female carriers of hereditary or acquired thrombophilias. The aim of the study was to determine if carriership of the factor V (FV) Leiden mutation (activated protein C [APC] resistance) is higher in women who have had of placental abruption during pregnancy. Design A retrospective case-control study. Setting Un

The most important issue in this dissertation will be a discussion concerning metal age flint use in Scania. Since flint tools from the Bronze and Iron Ages and Medieval times have rarely been examined, there are few general guidelines in typology or morphology. It is quite clear that conversions of existing Stone Age typological schemes are unsuitable when one intends to study the often simple an

BACKGROUND: Chest pain is one of the most common complaints in the Emergency Department (ED), but the cost of ED chest pain patients is unclear. The aim of this study was to describe the direct hospital costs for unselected chest pain patients attending the emergency department (ED). METHODS: 1,000 consecutive ED visits of patients with chest pain were retrospectively included. Costs directly foll

OBJECTIVE: To determine the diagnostic value of metaiodobenzylguanidine (MIBG) scintigraphy compared with computed tomography (CT) for the localization of phaeochromocytomas in clinical practice. DESIGN: Retrospective comparison between MIBG scintigrams and CT for localization of phaeochromocytomas in all patients successively examined with MIBG scintigraphy in Malmo from 1984 until January 1997.