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Determining Appropriate Design Impact Loads to Roadside Structures Using Stochastic Modeling

The design and verification of built structures requires structural engineers to consider accidental loading situations. The accidental loading situation investigated in this paper is heavy-goods vehicle (HGV) collisions with roadside structures; focus is on the design of bridge-supporting structures. The impact loads were determined from Monte Carlo simulations of a probabilistic model in which h

The Autism-Tics, AD/HD and other Comorbidities (A-TAC) telephone interview: Convergence with the Child Behavior Checklist (CBCL).

Objective: To compare telephone interview screening for child psychiatric/neuropsychiatric disorders using the inventory of Autism-Tics, Attention deficit/hyperactivity disorder (AD/HD) and other Comorbidities (A-TAC) with results from the Child Behavior Checklist (CBCL). Background: The A-TAC is a parent telephone interview focusing on autism spectrum disorders (ASDs) and co-existing problems, de

Expression profiling of cell cycle genes in human pancreatic islets with and without type 2 diabetes.

Microarray gene expression data were used to analyze the expression pattern of cyclin, cyclin-dependent kinase (CDKs) and cyclin-dependent kinase inhibitor (CDKIs) genes from human pancreatic islets with and without type 2 diabetes (T2D). Of the cyclin genes, CCNI was the most expressed. Data obtained from microarray and qRT-PCR showed higher expression of CCND1 in diabetic islets. Among the CDKs,

Should heritage management be democratized? The Denkmalpflegediskussion in Germany.

This paper is about the recent discussions (known as Denkmalpflegediskussion) on the general organization of heritage management in Germany. The main issue discussed was whether heritage management should be further denationalized (’entstaatlicht’) and made the responsibility of individual citizens in order to serve better both the monuments and the people. A number of fundamental criticisms were

Living with cancer in old age. Quality of life and meaning.

The overall aim of this thesis was to investigate quality of life in people aged 75 and older with cancer in relation to age, gender, presence and type of complaints, comorbidity, living conditions, perceived economic situation, sense of coherence, receiving help for daily living and social resources. The aim was also to investigate older people’s experiences and the meaning of living with cancer

Childhood malignant disease and consequences for growth hormone secretion, intellectual function and cardiovascular risk

In childhood onset growth hormone deficiency (GHD) a reduction in cardiac left ventricular mass (LVMi) and impairment of cardiac systolic function, as well as in glomerular filtration rate (GFR) has been shown. In study I, we showed that a low dose of GH treatment for 10 months resulted in increased LVMi and kidney size. No significant improvement in cardiac systolic function or GFR, except for a

Outcome indicators for the evaluation of energy policy instruments and technical change

The aim of this paper is to propose a framework for the evaluation of policy instruments designed to affect development and dissemination of new energy technologies. The evaluation approach is based on the analysis of selected outcome indicators describing the process of technical change, i.e. the development and dissemination of new energy technologies, on the basis of a socio-technical systems a

Levels of C-14 in the terrestrial environment in the vicinity of two European nuclear power plants

Radiocarbon is produced in all types of nuclear reactors. Most of the C-14 released into the environment is in the form of gaseous emissions. Recent data on the C-14 concentration found in terrestrial samples taken in the vicinity of nuclear power plants in Romania and Lithuania are presented. We found increased C-14 levels in the surroundings of both power plants. At the Romanian power plant Cern

hTERT T-1327/C polymorphism is not associated with age-related telomere attrition in peripheral blood

Regulation of the telomerase catalytic subunit, hTERT, is a complex process accomplished on many levels. Transcription of the hTERT gene has been widely studied but less is known about the implication of genetic variations. Recently, a functional T to C transition polymorphisin was indicated 1327 bp upstream the hTERT transcription starting site. The C-1327/C genotype was associated with shorter t