Transnational actors such as the European Union, encourages and promotes the development of circular economics. The rationale is financially based, but it also comes from a perspective of sustainability. Funding is provided to programmes and projects with this intent in mind. Symbiosis is a concept within circular economics in which public and private actors can utilize each other’s residuals and

The term Smart City is a frequently used term regarding cities' modern ICT solutions that contribute towards sustainable development and the improvement of the life quality of citizens. However, Smart City incorporates several areas of which can make a city smarter and is considered ambiguous in its very definition. This thesis aims to discover the issues related to the lack of a standard defi

Noting a need for a closer understanding of the discrepancy between the actions that sustainable smartphone applications encourage and the actions that the users perform, this thesis explores the implications for sustainable consumption practices. This thesis takes a sociological approach to markets, focusing on three key concepts (market devices, socio-technical scripts, qualification) to answer

Avfallskampanjer behöver kombineras med andra politiska styrmedel för att bli mer effektiva Varför prioriterar individer ofta materialåtervinning över avfallsförebyggande arbete? Denna studie undersöker om det finns ett samband mellan hur mycket resurser som läggs på informationskampanjer om materialåtervinning och avfallsförebyggande kampanjer med hur individer väljer att agera i dessa frågor. A

Intra-islet crosstalk has become a focus area to fully understand the regulation of insulin secretion and impaired β-cell function in type 2 diabetes (T2D). Here, we put forward evidence for insulin-like growth factor binding protein 7 (IGFBP7) as a potential protein involved in autocrine and paracrine β-cell regulation. We showed presence of IGFBP7 in granules of both human α- and β-cells and mea

The activities of cluster initiatives operating as systemic intermediaries and supporting networking activities have been discussed in prior studies. We integrate insights from the cluster theory and the literature on sustainability transitions to study the activities of clusters acting as systemic intermediaries in the different phases of the development of a forest-based bioeconomy, namely (1) p

Brain insulin resistance links the failure of energy metabolism with cognitive decline in both type 2 Diabetes Mellitus (T2D) and Alzheimer's disease (AD), although the molecular changes preceding overt brain insulin resistance remain unexplored. Abnormal biliverdin reductase-A (BVR-A) levels were observed in both T2D and AD and were associated with insulin resistance. Here, we demonstrate that re

BACKGROUND:Postural orthostatic tachycardia syndrome (POTS) is a frequently diagnosed cardiovascular disorder after COVID-19 infection. POTS is characterized by the presence of excessive sinus tachycardia on standing without a fall in blood pressure (BP). We investigated the BP profile using 24-hour ambulatory BP monitoring in patients with new-onset POTS after COVID-19 compared with prepandemic p

Rheumatoid arthritis (RA) involves several classes of pathogenic autoantibodies, some of which react with type-II collagen (COL2) in articular cartilage. We previously described a subset of COL2 antibodies targeting the F4 epitope (ERGLKGHRGFT) that could be regulatory. Here, using phage display, we developed recombinant antibodies against this epitope and examined the underlying mechanism of acti

Cells have an incredible ability to physically interact with neighboring cells and their environment. They can detect and respond to mechanical forces by converting mechanical stimuli into biochemical signals in a process known as mechanotransduction. This is a key process for the adaption of vascular smooth muscle and endothelial cells to altered flow and pressure conditions. Mechanical stimuli,

Digital technologies are increasingly common in language learning. Online media creation provides scope for agency and spaces for identity construction, but empirically grounded conceptualizations of the influences on learners' motivation are lacking and the digital technology–second language motivation interface remains largely unexplored. Using a grounded theory ethnographic approach (Charmaz,20

English is today learnt in multitudes of settings worldwide, making it difficult to characterize relationships between motivation and context in generalized terms (Ushioda 2013). In settings where students have extensive encounters with English outside school, a reluctance to invest effort in formal learning has been observed. To investigate ways in which out-of-school encounters impact on motivat

L2 motivation research has a longstanding monolingual bias. Recently, however, the motivational systems of a multilingual’s different languages have been conceptualized as constituting a multilingual motivational system, and it has been suggested that interactions between the ideal Lx self and the ideal Ly self can lead to the emergence of an ideal multilingual self. While the notion of an ideal m

Resection of advanced rectal cancer might result in significant tissue loss, including pelvic floor and parts of the vaginal wall. Pelvic floor reconstruction using a musculocutaneous flap offers optimized healing abilities and the possibility of vaginal reconstruction. In Skåne University Hospital, two different flap techniques are used to reconstruct the perineum: the vertical rectus abdominis m

The PNPLA3 I148M variant is the major genetic risk factor for all stages of fatty liver disease, but the underlying pathophysiology remains unclear. We studied the effect of this variant on hepatic metabolism in homozygous carriers and non-carriers under multiple physiological conditions with state-of-the-art stable isotope techniques. After an overnight fast, carriers had higher plasma β-hydroxyb

Social trust is a heritable trait that has been linked with physical health and longevity. In this study, we performed genome-wide association studies of self-reported social trust in n = 33,882 Danish blood donors. We observed genome-wide and local evidence of genetic similarity with other brain-related phenotypes and estimated the single nucleotide polymorphism-based heritability of trust to be