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The intracellular helical bundle of human glucose transporter GLUT4 is important for complex formation with ASPL

Glucose transporters (GLUTs) are responsible for transporting hexose molecules across cellular membranes. In adipocytes, insulin stimulates glucose uptake by redistributing GLUT4 to the plasma membrane. In unstimulated adipose-like mouse cell lines, GLUT4 is known to be retained intracellularly by binding to TUG protein, while upon insulin stimulation, GLUT4 dissociates from TUG. Here, we report t

Forecasting snow and black ice growth from temperature and precipitation

Growth of ice and the type of ice that is formed have environmental impact on a lake. Although ice growth is reasonably well estimated by the degree-day method, this method does not allow to distinguish between different types of ice. In this paper, an algorithm or model is suggested for computing black and white ice growth and lake snowcover depth. Input is daily values of air temperature and pre

Evaluation of Glycosaminoglycans Biological Age in Cells and Tissues

Bomb pulse refers to the sharp increase of the atmospheric levels of the carbon isotope 14C due to nuclear testing during the late 1950s and early 1960s. After the nuclear test ban, atmospheric 14C levels decreased exponentially because of the diffusion and equilibration with the ocean and biosphere, as well as the incorporation indirectly into all living cells. Thus, assessing the anthropogenic

Voices of Supporters : Populist parties, social media and the 2019 European elections

This book addresses an under-researched area within populism studies: the discourse of supporters of populist parties. Taking the 2019 European elections as their case study, the authors analyse how supporters in eleven different countries construct identities and voting motivations on social media. The individual chapters comprise a range of methods to investigate data from different social mediaThis book addresses an under-researched area within populism studies: the discourse of supporters of populist parties. Taking the 2019 European elections as their case study, the authors analyse how supporters in eleven different countries construct identities and voting motivations on social media. The individual chapters comprise a range of methods to investigate data from different social media

Nordic Perspectives on the Discourse of Things : Sakprosa Texts Helping Us Navigate and Understand an Ever-changing Reality

This open access book deals with the role of written texts in an increasingly diverse and dynamic society, bringing together a series of studies anchored in the Scandinavian research tradition of sakprosa, which roughly translates as ‘subject-oriented prose’ or ‘professional communication’. The authors examine the written text’s capacity to transcend contextual boundaries, as a crucial factor in t

DAVID : An open-source platform for real-time transformation of infra-segmental emotional cues in running speech

We present an open-source software platform that transforms emotional cues expressed by speech signals using audio effects like pitch shifting, inflection, vibrato, and filtering. The emotional transformations can be applied to any audio file, but can also run in real time, using live input from a microphone, with less than 20-ms latency. We anticipate that this tool will be useful for the study o

Standards, Barriers to Trade and EU Internal Market Rules : Need for a Renewed Approach?

In light of the speedy technological development in society, technical standards are becoming increasingly important. In the early days, the specific tasks delegated to standardization bodies under the New Approach did not attract much political interest. Today, however, politicians and different stakeholders realize that the tasks delegated to the standardization industry are highly important for

Spain: an extreme case of successful integration of second-generation immigrants with transfers of best practices applicable to other European countries?

This volume presents cutting-edge research on integration and adaptation processes of second-generation immigrant adolescents in Spain that no doubt constitutes an important and timely contribution to the migration-integration debate. Principal findings of the Investigación Longitudinal de la Segunda Generación study indicate a comparatively smooth integration of second-generation immigrant adoles

LONG-TERM MODELLING OF AEOLIAN TRANSPORT AND BEACH-DUNE EVOLUTION

A model to simulate long-term beach-dune evolution due to interacting longshore and cross-shore sediment transport processes is developed and tested. The work builds on a cross-shore model (CSM) previously developed at Lund University and includes changes to the equations describing aeolian transport and morphological evolution. The modifications are mainly based on existing conceptual geomorpholo

Educational Assortative Mating and Household Division of Labor : A pan-European Perspective

Educational homogamy has been increasing for a long time in the Western world but there has been much more research on describing and explaining this trend than actually looking at its consequences. Economic theory predicts that educational heterogamy is related to division of labor in accordance with comparative advantages in household and market production, but there has been few tests of this h

Circadian repressors CRY1 and CRY2 broadly interact with nuclear receptors and modulate transcriptional activity

Nuclear hormone receptors (NRs) regulate physiology by sensing lipophilic ligands and adapting cellular transcription appropriately. A growing understanding of the impact of circadian clocks on mammalian transcription has sparked interest in the interregulation of transcriptional programs. Mammalian clocks are based on a transcriptional feedback loop featuring the transcriptional activators circad

Advocacy Compromised : How Financial, Organizational and Institutional Factors Shape Advocacy Strategies of Civil Society Organizations

Key functions of civil society organizations (CSOs) are to criticize governments and to hold them to account. Recent trends of privatization and contracting out challenge CSOs’ opportunities to voice such criticism. The purpose of this article is to analyse whether and why CSOs ‘hold back their criticism’ of public authorities, and how a compromised advocacy can be linked to financial, organizatio