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Utvecklingen inom gentekniken har gjort det möjligt att inom sjukvårdens ram undersöka många gener samtidigt genom helgenom-/helexomanalyser. Detta har hittills främst utnyttjats för diagnostik av personer, framför allt barn, med misstänkt ärftliga syndrom.Under de senaste tre åren har tekniken utnyttjats för att bygga upp plattformar att användas för kartläggning av recessiva sjukdomsanlag hos fr

Det skjutvapenrelaterade våldet i Sverige har ökat kraftigt sedan 1990-talet, och trots att hela Sverige är drabbat sticker Region Skåne och då främst Malmö ut. Även om en stor del av skottlossningarna riktas mot byggnader och fordon dör och skadas årligen ett tiotal personer i staden. Även explosionsvåldet har ökat både i landet och i Malmö och det kan vara ett tecken på ett trendbrott inom den g

Treatment with IgG against the malondialdehyde (MDA)-modified apolipoprotein B-100 epitope p45 reduces atherosclerosis in experimental models. This study investigated the association between p45 IgG autoantibodies and plaque inflammation in subjects with advanced cardiovascular disease.

Genetic risk scores (GRSs) have been associated with coronary heart disease (CHD) in large studies. We asked whether expanding an established 27-variant GRS (GRS27) to a 50-variant GRS (GRS50) improved CHD prediction and whether GRSs are independent of self-reported family history of CHD.

Individuals who had a low birthweight (LBW) are at an increased risk of insulin resistance and type 2 diabetes when exposed to high-fat overfeeding (HFO). We studied genome-wide mRNA expression and DNA methylation in subcutaneous adipose tissue (SAT) after 5 days of HFO and after a control diet in 40 young men, of whom 16 had LBW.

The conflicts concerning the preservation or destruction of the deserted church of Mårup in Denmark is followed from the the moment in 1928, when the church became redundant, untill 2004. The protection of the church is in conflict with the protection of the eroding cliff, the church as a symbol in conflict with the church as a source material, and the local people in conflict with central authori

Partial wh-movement does not exist in the modern Scandinavian languages. It is however found in Old West Scandinavian texts, but not in Old East Scandinavian texts. In this article it is argued that there is a correspondence between attested partial wh-movement and the possibility of deleting the complementizer corresponding to English that. Although complementizer deletion is possible in all mode

Genetic variation in the cluster on chromosome 15, encoding the nicotinic acetylcholine receptor subunits (CHRNA5-CHRNA3-CHRNB4), has shown strong associations with tobacco consumption and an additional risk increase in smoking-related diseases such as chronic obstructive pulmonary disease (COPD), peripheral artery disease and lung cancer.

The resistivity method is well suited for dam monitoring as it is non-destructive and easily adapted for long-term monitoring. Measurements detect changes of material properties as well as anomalous variations, which may relate to internal erosion and seepage. However, applying the resistivity method on embankment dams can be challenging. This paper contends with practical use of the resistivity m

This paper presents an ongoing work concerning the development of a theoretical framework for design. The framework is intended to be applied to the development of information systems for architectural design. The paper combines ontological and epistemological perspectives using Bunge’s work as a starting point, supplemented with Schön’s studies of the general nature of design, and with examples o