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The G-protein coupled receptor CMKLR1/ChemR23: Studies on gene regulation, receptor ligand activation, and HIV/SIV co-receptor function

In all higher organisms, there is a need for intercellular communication. G-protein coupled receptors (GPCRs), located on the cell surface, play an important role in this communication. Cells synthesize and release signalling molecules (ligands), which produce a specific response only in those cells that have a receptor for that ligand. The total number of GPCRs is estimated to be around 800 where

Activation of human B cells with the Moraxella catarrhalis IgD-binding protein MID

Moraxella catarrhalis is a respiratory tract pathogen that causes significant health problems, including acute otitis media in children, lower respiratory tract infections in adults and the elderly and sinusitis in both children and adults. The interest in M. catarrhalis bacteria has increased over the past 20 years, both because of the emergence of the bacteria as a human pathogen and because of

No title

The aim of this thesis is to investigate the relation between intrasubjective mental representations – ‘conceptual structures’ – and their intersubjectively available material manifestation, in particular morphosyntactic representations. Such an investigation presupposes the analysis of not only extralinguistically established modules but also of structural levels that are inherent components of t

Functional Recovery after Experimental Stroke in Mice- Involvement of Enriched Environment, BDNF and Cell Genesis

Stroke is caused by an obstruction of blood flow to a part of the brain, resulting in brain damage. Stroke is the third most common cause of death in the industrialized world, and the primary cause of adult-onset disability. There is a spontaneous recovery of function after stroke but several factors, such as the environment can influence the speed and extent of this recovery. This thesis deals wi

Brandvägg. Ord och handling i en yrkesutbildning

Brandvägg describes how a group of firefighters, who consistently maintain that they are “practitioners and not theorists”, relate to various forms of language based knowledge and language based “knowledging” in their vocational training, which is based on problem based learning. From a sociocultural perspective to learning, and within the parameters of a didactic perspective with the focus on the

Influence of lifestyle behaviours on bone mineral density among young healthy women: A two-year study. A Tentative Salutary Model.

The overall aim of this prospective observational study with a salutogenic approach was to investigate bone mineral density (BMD) and BMD changes in the heel bone, in a group of healthy women, in relation to physiological factors and lifestyle behaviours over a two-year period as well as investigating the women’s view of their lifestyle behaviours. Data were collected in 1999 (T1) and 2001 (T2). H

Industrial Management Models with Emphasis on Construction Waste

Increased attention is nowadays devoted to waste management. The objective of this work is to analyse how commonly known business economic models and methods, as well as the Polluter-Pays Principle, can be applied to waste management in general and to waste fractionation in particular, so as to facilitate environmental optimisation of industrial and construction waste fractionation. In discussing

Leva med stroke - lära av erfarenheter

This thesis concerns how people with stroke describe their experiences of life with stroke and how they learn to live with stroke. In the western world the interest for research in lived experiences has increased. This might be due to the higher rate of people with illness and lifelong diseases. The aim of the study is to analyze stories from persons with stroke of their lived experiences of life

Indonesian Literature vs New Order Orthodoxy. The Aftermath of 1965-1966.

Starting from Theodor Adorno´s assertion that art is negative knowledge of the real world, the book analyses Indonesian literature produced during the New Order which deal with the events of 1965-1966 and its consequences. A number of Indonesia´s best known authors have written on the subject. The central issue raised is the extent to which this literature has contributed to undermining and thereb

En bonadsmålare och hans värld. Johannes Nilsson i Breared

The aim of this dissertation is to find relationships between folk art, an artist's personal life and influential factors originating in the context. Christmas wall hangings by the peasant painter Johannes Nilsson (1757­1827) are the focus of the study. The fact that he had a special approach to the painting tradition raises two questions: Why did he paint the way he did? How can his hangings be i

Bacterial Activity and Community Composition in the Rhizosphere. Influence of plant species, root age, nitrogen addition and mycorrhizal status

Microbial activity in soil is generally assumed to be limited by carbon availability. The soil closest to roots, the rhizosphere, is therefore a zone of high microbial activity due to carbon containing substances released by the root. In this work short-term effects in the rhizosphere have been the subject of investigation. I have shown that the thymidine and leucine incorporation techniques are w

Development and Characterisation of a Laser-Based Hard X-Ray Source

A laser-produced plasma was generated by focusing 100 fs laser pulses, with an energy of 150 mJ, onto metal targets. The laser intensity was expected to reach 10E17 W/cm2. Radiation was emitted from the created plasma, with photon energies extending up to the MeV regime. The laser-based X-ray source was optimised, with the purpose of making it a realistic source of hard X-rays (>10 keV). Dedicated

Telomeric DNA in Chironomus, a naturally telomerase-free system

Telomeres are specialized complexes of DNA and associated proteins that protect the ends of eukaryotic chromosomes. Although most organisms have short repeated DNA sequences at their telomeres, which are specified and maintained by the enzyme telomerase, there are a few exceptions. Dipteran insects, including the genus Chironomus (non-biting midges), lack telomerase and have atypical terminal sequ

Species interactions govern evolutionary and ecological effects of population harvesting

Harvesting changes population abundance and can affect adaptation of several life-history traits. Harvesting can also have indirect effects ? effects on non-target species and secondary effects on target species ? because interactions between species in a community determine the relevant ecological and evolutionary feedback environment. Species interactions therefore influence the effect of harves

Voluntary activation of skeletal muscle in young and old women and men

The evaluation of skeletal muscle strength is an important part of the physiotherapist’s clinical examination in order to plan and execute appropriate interventions. This requires the objective assessment of muscle strength and the determination of the underlying factors of muscle weakness. One factor that can contribute to muscle weakness is the inability of the central nervous system to voluntar

Investigation of Carbohydrate Hydrolysing Enzymes in Applications for Characterisation and Synthesis of Carbohydrates

Cellulose and starch are non-toxic, biodegradable and modifiable polymers. These properties have made them increasingly important in industrial products e. g. in pharmaceutical applications and in technical dispersions. By chemical modification of these polymers the physical and chemical properties of the polymer can be adjusted to suit a certain area of application. The characteristics of modifie

Proton-Conducting Sulfonated and Phosphonated Polymers and Fuel Cell Membranes by Chemical Modification of Polysulfones

The proton exchange membrane fuel cell (PEMFC) is currently emerging as an efficient and environmentally friendly power source. The technology is very complex and relies ultimately on materials and components which need further development. One of the major hurdles for advancing the PEMFC technology is currently the demand for new durable low-cost polymeric membranes that will allow fuel cell oper

Discovery of Novel Receptors for Lipid Mediators - a study leading to the identification of receptors involved in metabolism and the immune system

Intercellular communication is of crucial importance in regulating physiology and G-protein coupled receptors (GPCRs) have evolved as an important mechanism in this process. Of the approximately 800 human GPCRs, about 160 are still considered to be “orphan” receptors for which an endogenous ligand remains to be identified. Since an estimated 50% of all clinical drugs act on 30 known GPCRs, the rem

81 10262018 679 81 MP86 Kemppainen JAMA Ped 2017

Untitled Association Between Early-Life Antibiotic Use and the Risk of Islet or Celiac Disease Autoimmunity Kaisa M. Kemppainen, PhD; Kendra Vehik, PhD; Kristian F. Lynch, PhD; Helena Elding Larsson, MD, PhD; Ronald J. Canepa, BSc; Ville Simell, MSc; Sibylle Koletzko, MD, PhD; Edwin Liu, MD; Olli G. Simell, MD, PhD; Jorma Toppari, MD, PhD; Anette G. Ziegler, MD, PhD; Marian J. Rewers, MD, PhD; Åke

https://www.teddy.lu.se/sites/teddy.lu.se/files/2021-11/81%2010262018_679_81_MP86_Kemppainen_JAMA%20Ped_2017.pdf - 2025-07-13

Rules-of-procedure-for-lund-university

Rules of Procedure for Lund University Page 1 of 36 University Board DECISION Registration number STYR 2018/1859 STYR 2019/907 STYR 2019/1903 STYR 2020/2283 STYR 2021/2702 STYR 2022/1481 STYR 2023/1118 STYR 2024/2086 18 September 2024 Rules of Procedure for Lund University Approved by the University Board on 14 December 2018, item 12. Revised by the University Board on 18 September 2024, item 7, a

https://www.staff.lu.se/sites/staff.lu.se/files/2025-02/rules-of-procedure-for-lund-university.pdf - 2025-07-13