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Biocompatibility testing of medical devices is governed by the ISO 10993 series of standards and includes evaluation of skin sensitization potential of the final product. A majority of all medical devices are tested using in vivo methods, largely due to the lack of in vitro methods validated within the applicability domain of solid materials. The GARDskin method for assessment of chemical skin sen

Background-Considerable variability exists in the use of pharmacological thromboprophylaxis among acutely ill medical patients, partly because clinically relevant end points have not been fully assessed in this population. We undertook an international, multicenter, randomized, double-blind, placebo-controlled trial using clinically important outcomes to assess the efficacy and safety of daltepari

Background Detecting cognitive impairment in medical inpatients is important due to its association with adverse outcomes. Our aim was to study recognition of cognitive impairment and its association with mortality. Methods 200 inpatients aged over 60 years were recruited at the Department of General Internal Medicine at University Hospital MAS in Malmö, Sweden. The MMSE (Mini-Mental State Exami

Popular Abstract in Swedish Diabetes mellitus är en kronisk sjukdom som orsakas av en oförmåga att bilda och/eller känna av insulinets effekt i vävnaderna, vilket leder till förhöjda blodsockervärden. Diabetes som debuterar i unga år och där insulinproduktionen oftast är upphävd klassas som typ 1 diabetes. Typ 2 diabetes debuterar senare i livet och här finns olika grader av insulinproduktion kvarDiabetic retinopathy is a common complication to diabetes mellitus and is still a major cause of impaired vision in the Western world. The aim of the present study was to identify medical risk factors influencing the development and progression of retinopathy in type 1 diabetic patients, and to investigate the effects of laser treatment on visual acuity and glare. Although the development of sigh

Background: Atrial fibrillation (AF) in patients with Wolff-Parkinson-White (WPW) syndrome is potentially life-threatening as it may deteriorate into ventricular fibrillation. The aim of this study was to assess whether the emergency medical team members are able to diagnose AF with a rapid ventricular response due to the presence of atrioventricular bypass tract in WPW syndrome. Methods: The stud

The Medical Patients with Enoxaparin (MEDENOX) trial was a randomized, placebo-controlled study that defined the risk of venous thromboembolism (VTE) in acutely ill, immobilized, general medical patients and the efficacy of the low-molecular-weight heparin, enoxaparin, in preventing thrombosis. We performed a post-hoc analysis to evaluate the effect of 40 mg enoxaparin once daily on MEDENOX patien

Background: The prevalence of contact allergy in individuals with diabetes and diabetes medical device (MD) users is unknown. Objectives: This study (Part 1 and 2) aims at describing contact allergy prevalences in diabetes MD users. Methods: Adults with type 1 diabetes from two endocrinology departments were patch tested with the Swedish baseline series (SBS) and a MD series. Contact allergies to

Purpose: Despite availability of multimodal treatment options for acromegaly, achievement of long-term disease control is suboptimal in a significant number of patients. Furthermore, disease control as defined by biochemical normalization may not always show concordance with disease-related symptoms or patient’s perceived quality of life. We developed and validated a tool to measure disease activi

Context: The study of discourses (i.e. verbal interactions or written accounts) is increasingly used in social sciences to gain insight into issues connected to discourse, such as meanings, behaviours and actions. This paper situates discourse analysis in medical education, based on a framework developed in organisational discourse analysis and widely deployed in other social science disciplines.

We all make decisions, but when medical professionals do it, it can literally mean life or death. Decisions are influenced by many factors. The aim of the present study was to investigate if personality traits as proposed by the Big Five Model influence the Rational and Experiential cognitive information processing styles as proposed by the dual-process Cognitive-Experiential Self-Theory theory in

This study looks at how an Indian voluntary organization, the Punjab-based Guru Nanak Trust, is influenced by its supporters in the Sikh Diaspora. Guiding arguments from studies on Diaspora-Homeland relations were used to examine whether the Trust's linkages with the globally dispersed Punjabi community are getting stronger or weaker and what further opportunities there are for the Trust to in

This article traces the emergence of juvenile delinquency as a legal and medical category in Hashemite Iraq (1921–58). We argue that as children and youth became increasingly visible through actions and inactions that highlighted the weaknesses of political and social structures, state institutions adopted international frameworks and vernaculars concerning the participation of youth in labor. Med