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B cell activation by outer membrane vesicles--a novel virulence mechanism.

Secretion of outer membrane vesicles (OMV) is an intriguing phenomenon of Gram-negative bacteria and has been suggested to play a role as virulence factors. The respiratory pathogens Moraxella catarrhalis reside in tonsils adjacent to B cells, and we have previously shown that M. catarrhalis induce a T cell independent B cell response by the immunoglobulin (Ig) D-binding superantigen MID. Here we

Plasma concentrations of Gas6 (growth arrest specific protein 6) and its soluble tyrosine kinase receptor sAxl in sepsis and systemic inflammatory response syndromes

Introduction: Gas6, the protein product of the growth arrest specific gene 6, is present in human circulation at subnanomolar concentrations. It is secreted by endothelial cells and is important for the activation of endothelium during inflammation. Axl, the tyrosine kinase receptor for Gas6, is also present in endothelium and can be cleaved and released into the circulation. The soluble of form A

Studies of the role of complement factor H in hemolytic uremic syndrome

Popular Abstract in Swedish Faktor H är den viktigaste cirkulerande hämmare av den alternativa komplementvägen. Den fungerar som co-faktor för faktor-I medierad C3b nedbrytning, hindrar bildning av C3bBb konvertas och främjar dess nedbrytning. Genom att skilja mellan kroppens egna och främmande celler kan faktor H inhibera komplementmedierad värdcellsskada. Mutationer i faktor H har hittats hos paFactor H is the main fluid phase regulator of the alternative pathway of complement. Factor H acts as a co-factor for factor I-mediated C3b degradation, inhibits the formation of the C3bBb convertase and accelerates its decay. By discriminating between host and foreign cells, factor H inhibits complement-mediated injury to host cells. Factor H mutations have been associated with atypical hemolytic

Biomarkers in lower respiratory tract samples in the diagnosis of ventilator-associated pneumonia : a systematic review

BACKGROUND: Ventilator-associated pneumonia (VAP) is the most common intensive care unit-acquired infection, yet its diagnosis is complicated by the lack of reliable diagnostic criteria and validated biomarkers. Due to the compartmentalisation of the immune response, host proteins in respiratory tract samples are more likely than serum proteins to accurately identify VAP. However, a reliable bioma

Analysing inclusivity within small town development in Uganda and Tanzania : an inclusivity index and experiential insights

Framed within debates about the inclusivity of urban development, Ubuntu philosophy and an interest in non-metropolitan growth of ordinary places, 15 small but developing towns were selected across Uganda and Tanzania. Growth and development were evidenced by increase in night-time lights and densification/expansion of built-up areas. Analysis of c. 4,000 individuals asked which towns were more, o

Aquaporins : Chemical inhibition by small molecules

The human genome encodes 13 aquaporin isoforms with characteristic substrate specificity that are expressed at specific locations throughout the body. Of these isoforms, AQPs 1-4 serve important functions in renal water reabsorption. Consequently, specific AQP inhibitors have been proposed as 'aquaretics', a new class of drugs suitable to induce diuresis without concomitant salt wasting. Furthermo

Mental representations of important real-life decisions

Two studies investigated how decision makers characterize alternatives in important real-life decisions, which they themselves had made (to leave a partner, to choose an education and to choose a home). First, the participants indicated a very high degree of involvement in the decisions studied and about half of the participants gave maximum involvement ratings for the partner decision. Second, th

The Oncogene ECT2 Contributes to a Hyperplastic, Proliferative Lung Epithelial Cell Phenotype in Idiopathic Pulmonary Fibrosis

Idiopathic pulmonary fibrosis (IPF) and lung cancer represent progressive lung diseases with a poor prognosis. IPF represents a risk factor for the development of lung cancer, and the incidence of lung cancer is increased in patients with IPF. Disease pathogenesis of IPF and lung cancer involves common genetic alterations, dysregulated pathways, and the emergence of hyperplastic and metaplastic ep

Immunoinformatics study of procyanidins as mast cell stabilizers

Background: Allergens are foreign proteins that stimulate the production of immunoglobulin E (IgE), when they come in contact with human body. These allergens after binding with IgE through FcεRI receptor, triggers the signal transduction reaction in mast cell and basophil cells, leading to allergic reactions by releasing some mediators. Four correctly written as surface-exposed tryptpphans Trp 87

No title

This study presents a spatial analysis of two regions in southern Iberia (Western Sierra Morena and Lands of Antequera) as a means to deepen our understanding of the Romanisation of the province Ulterior Baetica. Its theoretical foundations rely on the belief that human communities modify and adapt to their surroundings according to their changing needs (functional and symbolic, amongst many other

Carpal tunnel syndrome with severe sensory deficit: endoscopic release in 18 cases

Carpal tunnel syndrome (CTS) with severe sensory deficit was treated with endoscopic carpal tunnel release in 18 hands of 16 consecutive patients (median age 72 (28-92) years). In all hands, preoperative 2-point discrimination (2-PD) exceeded 15 mm in the radial and ulnar sides of the pulps of at least 2 of the 3 radial digits. All patients underwent an independent evaluation and answered a questi

Automated power test- Hardware testing of power consumption

For ensuring quality of a product it is important to perform hardware testing on a device. The aim of this thesis was to simplify and improve the process for power consumption hardware testing at a company. The result was one semi-automated and one fully automated solution. Another key component was that the system should have high flexibility, everything from the choice of instruments to the test

Modelbased Visual Servoing Grasping of Objects Moving by Newtonian Dynamics

Robot control systems are traditionally closed system. With the aid of vision, visual feedback is used to guide the robot manipulator to the target in a similar manner as humans do. This hand-to-target task is fairly easy if the target is static in Cartesian space. However, if the target is dynamics in motion, a model of this dynamical behaviour is required in order for the robot to predict or tra

Connected Health for Patients Diagnosed with Prostate Cancer

Prostate cancer is one of the most commonly diagnosed diseases among men, both in Sweden and the US. It is a consuming disease that tears on both the patient and his relatives. The different stages of disease are many, as are the different treatment options and drugs. New diagnostic techniques are constantly being developed and more imaging methods become available. As new digital techniques evolv

HMGB1 in severe soft tissue infections caused by Streptococcus pyogenes.

Extracellular High Mobility Group Box 1 (HMGB1) has been associated with acute and chronic inflammatory conditions. However, little is known about HMGB1 in necrotizing bacterial infections. We hypothesized that the local HMGB1 response is excessive in severe soft tissue infections (STIs), which are characterized by necrosis and hyperinflammation. To explore this, tissue biopsies were collected fro

Sensor Fusion for Dynamic Privacy Masking

This master thesis investigates the possibility of combining a regular visual surveillance camera with a thermal infrared surveillance camera monitoring the same view of a scene to detect and classify heat radiating objects such as human beings. A method is presented for the application of privacy masking of a window while detecting heat radiating objects between the cameras and the window and pre

Piccini et al ann neurol 2000 0

Delayed recovery of movement-related cortical function in Parkinson's disease after striatal dopaminergic grafts Delayed Recovery of Movement-Related Cortical Function in Parkinson’s Disease after Striatal Dopaminergic Grafts Paola Piccini, MD,* Olle Lindvall, MD, PhD,† Anders Björklund, MD, PhD,‡ Patrik Brundin, MD, PhD,§ Peter Hagell, RN, BSc,† Roberto Ceravolo, MD,* Wolfgang Oertel, MD,i Niall

https://www.wnc.lu.se/sites/wnc.lu.se/files/piccini_et_al_ann_neurol_2000_0.pdf - 2026-05-30

Papaya - overall policy brief e

Pre_press_Overall Policy Brief E - 15-05-17 PP.pdf Papaya Policy Brief E Policy for Equity in Central-Eastern Africa 2002 - 2017 Aida Isinika 1, Miriam Joshua2, Audrey Kalindi3, Elibariki Msuya4, Wapulumuka Mulwafu5, Mukata Wamulume6 and Martin Prowse7 The extent to which agricultural policy frameworks in Zambia, Tanzania and Malawi integrate gender and generation into intensification activities v

https://www.keg.lu.se/en/sites/keg.lu.se.en/files/papaya_-_overall_policy_brief_e.pdf - 2026-05-30

After completing my studies

After completing my studies | Student website LTH Skip to main content This site uses cookies to enhance the user experience. By continuing to use the site you agree that cookies are used according to our Cookie Policy (on the website of LTH) . Essential cookies These cookies are necessary for the website to function and cannot be turned off in our systems. These cookies do not store any personall

https://www.student.lth.se/english/exchange-students/after-completing-my-studies/ - 2026-05-28