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Neuropeptide Y autoantibodies in patients with long-term type 1 and type 2 diabetes and neuropathy.

Aims: The neurotransmitter Neuropeptide Y (NPY) was previously reported as a minor autoantigen in newly diagnosed type 1 diabetes (T1D) patients. The single nucleotide polymorphism at rs16139 (T1128C, L7P) in the NPY gene was associated with an increased risk for the development of type 2 diabetes (T2D). We aimed to develop a radiobinding assay for NPY-L (Leucine) and NPY-P (Proline) autoantibodie

Fatigue in out-patients with inflammatory bowel disease is common and multifactorial.

Background Patients with inflammatory bowel disease (IBD) often complain of fatigue. Aim To investigate the prevalence and characteristics of fatigue among IBD out-patients in Scandinavia and to provide normative values for fatigue in IBD patients. Methods A cross-sectional study was conducted on 425 IBD patients from six out-patient centres in Denmark, Norway and Sweden. Fatigue was measured usin

GP's Adherence to Guidelines for Cardiovascular Disease among Elderly: A Quality Development Study.

Background: Evidence-based guidelines should in most cases be followed also in the treatment of elderly. Older people are often suboptimally treated with the recommended drugs. Objectives: To describe how well general practitioners adhere to current guidelines in the treatment of elderly with cardiovascular disease and evaluate local education as a tool for improvement. Method: Data was colle

Cross-cultural validation of the ICOAP and physical function short forms of the HOOS and KOOS in a multi-country study of patients with hip and knee osteoarthritis

Objective To evaluate the internal consistency and construct validity of the Physical Function short-forms for the Hip and Knee Injury Osteoarthritis Outcome Scores (HOOS-PS/KOOS-PS) and the Intermittent and Constant Osteoarthritis Pain (ICOAP) in a nine country study of patients consulting for total hip or knee replacement (THR or TKR). Methods Patients completed HOOS-PS or KOOS-PS, ICOAP and Wes

Minor amputation does not negatively affect health-related quality of life as compared with conservative treatment in patients with a diabetic foot ulcer : An observational study

Background: Health-related quality of life (HRQoL) is poor in patients with persistent diabetic foot ulcers and poor HRQoL predicts worse outcomes in these patients. Amputation is often considered a treatment failure, which is why conservative treatment is generally preferred over amputation. However, it is unclear whether minor amputation negatively affects HRQoL compared with conservative treatm

From co2 measurements to carbon balance maps 0

Microsoft Word - ClimBEco_INES-course on carbon flux upscaling 20200121 (002) From CO2 in situ measurements to carbon balance maps as a tool support to national carbon accounting This is a course run by Dept. of Physical Geography and Ecosystem Science at Lund University with input from ICOS Carbon Portal and ICOS Sweden. The course is supported by ClimBEco and is included in the ClimBEco research

https://www.cec.lu.se/sites/cec.lu.se/files/from_co2_measurements_to_carbon_balance_maps_0.pdf - 2026-06-02

A machine learning tool for identifying patients with newly diagnosed diabetes in primary care

Background and aim: It is crucial to identify a diabetes diagnosis early. Create a predictive model utilizing machine learning (ML) to identify new cases of diabetes in primary health care (PHC). Methods: A case-control study utilizing data on PHC visits for sex-, age, and PHC-matched controls. Stochastic gradient boosting was used to construct a model for predicting cases of diabetes based on dia

Factors with independent influence on the 'timed up and go' test in patients with hip fracture.

Background and Purpose. Data on performance times for the 'timed up and go' (TUG) test with analyses of factors, that eventually could affect the result in patients with hip fracture, have not been published to date. The aims of the present study, therefore, were to assess normative reference values of TUG performances and determine the influence of individual and clinical factors on TUG-test scor

Prevalence and intensity of pain after stroke: a population based study focusing on patients' perspectives.

OBJECTIVE: To determine prevalence and intensity of pain after stroke, focusing on patients' perspectives. METHODS: During a one year period, 416 first-ever stroke patients were included in the population based Lund Stroke Register. After 4 and 16 months (median), 297 patients (98% of survivors) were followed up. Worst pain intensity during the previous 48 hours was assessed on a visual analo

Towards sustainable solid waste management in Jordan

Popular Abstract in English Jordan is a country with a rapidly growing economy, modernization and growing population. The rapid increase in volumes of solid wastes and a steady increase in the cost and logistical difficulties with the associated risk to human health is a source of concern. The increasing solid waste generated in Jordan has not been accompanied with adequate sanitation facilities aJordan is a country with a growing population that is undergoing rapid modernization. The increased volume of solid waste and associated logistical difficulties, the steady growth in the cost of waste management and the risk to human health are sources of concern. The increasing amount of solid waste generated in Jordan has not been accompanied by adequate sanitation facilities or management progr

Maf transcription factors in beta cell function

Popular Abstract in English According to the International Diabetes Federation (IDF), 415 million people suffer from diabetes worldwide. Diabetes occurs when the pancreatic beta cells are no longer able to produce or properly use insulin. Insulin regulates blood glucose levels by enabling glucose uptake into cells, providing the body with energy. Elevated glucose levels cause damages to highly vasDiabetes mellitus is metabolic disorder caused by a defect or lack of beta cell-produced insulin that controls blood glucose homeostasis. In addition to glucose, insulin secretion is regulated by the autonomic nervous system (ANS); the neurotransmitter acetylcholine as well as monoamines, such as dopamine, serotonin, melatonin and norepinephrine. Using a MafA mutant mouse model, we show that MafA

Human and Robot Narrator: How Gestures Affect Comprehension and Recollection

This thesis investigated if a human or a robot narrator affected listeners’ comprehension and memory recollection similarly in a narrative story. 103 participants (MeanAge = 35) were recruited to an online experiment to investigate if gestures affected the participants’ narrative comprehension and recollection more than a narrator that did not produce gestures. Participants were presented with the

Dizziness and localized pain are often concurrent in patients with balance or psychological disorders

Background and aims Symptoms of dizziness and pain are both common complaints and the two symptoms often seem to coincide. When symptoms appear concomitant for sustained periods of time the symptoms might maintain and even exacerbate each other, sometimes leading to psychological distress. In order to evaluate such comorbidity we studied patients referred to a vestibular unit and to a psychiatric

Trajectory-Ordered Objectives for Self-Supervised Representation Learning of Temporal Healthcare Data Using Transformers : Model Development and Evaluation Study

Background: The growing availability of electronic health records (EHRs) presents an opportunity to enhance patient care by uncovering hidden health risks and improving informed decisions through advanced deep learning methods. However, modeling EHR sequential data, that is, patient trajectories, is challenging due to the evolving relationships between diagnoses and treatments over time. Significa

146 Vehik Diab Care 2022 3

DB22en08_proof.pdf Kendra Vehik,1 David Boulware,1 Michael Killian,2 Marian Rewers,3 Richard McIndoe,4 Jorma Toppari,5 Åke Lernmark,6 Beena Akolkar,7 Anette-G Ziegler,8 Henry Rodriguez,9 Desmond A. Schatz,10 Jeffrey P. Krischer,1 and William Hagopian,2 for the TrialNet Study Group and TEDDY Study Group* Rising Hemoglobin A1c in the Nondiabetic Range Predicts Progression of Type 1 Diabetes As Well

https://www.teddy.lu.se/sites/teddy.lu.se/files/2023-04/146%20Vehik_Diab%20Care_2022_3.pdf - 2026-06-02

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2 June 2022 Call for Proposals Consultancy to Undertake a Gender Mainstreaming Assessment of the RWI Kenya Programme The Raoul Wallenberg Institute of Human Rights and Humanitarian Law, Nairobi Office (RWI) invites proposals for Consultancy services to undertake a Gender Assessment of the Kenya Programme, This is a competitive process and suitable candidates shall be sourced through an open call a

https://rwi.lu.se/wp-content/uploads/2022/06/RWI-Nairobi-Gender-assessement-ToR_Final-02062022.pdf - 2026-06-02

Visual observation of postural orientation with two-dimensional footage in a healthy physically active population – using a predefined test battery and rating scale

Background The two main functional goals of postural control are postural stability (balance) and postural orientation. Postural orientation is the ability to maintain alignment between body segments and the environment during a static or dynamic activity. Nae et al. have evaluated the measurement properties of a clinical test battery for assessing postural orientation errors (POEs) in patients wi

CIPSS-2023-2024

Co-Design for Sustainable, Resilient and Inclusive Public Spaces and Services - CIPSS 2023–2024 Innovation and Co-design for Sustainable, Resilient and Inclusive Public Spaces and Services (CIPSS) 2023–2024 The programme aims to increase the capacity of municipal officials to co-design inclusive public services and physical and digital spaces through improved municipal service provisions and socia

https://www.lunduniversity.lu.se/sites/www.lunduniversity.lu.se/files/2023-02/CIPSS-2023-2024.pdf - 2026-06-02