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Nurse-led heart failure clinics improve survival and self-care behaviour in patients with heart failure - Results from a prospective, randomised trial

Aim The aim of this trial was to prospectively evaluate the effect of follow-up at a nurse-led heart failure clinic on mortality, morbidity and self-care behaviour for patients hospitalised due to heart failure for 12 months after discharge. Methods A total of 106 patients were randomly assigned to either follow-up at a nurse-led heart failure clinic or to usual care. The nurse-led heart failure c

Attending Heart School and long-term outcome after myocardial infarction : A decennial SWEDEHEART registry study

Background: The Heart School is a standard component of cardiac rehabilitation after myocardial infarction in Sweden. The group-based educational intervention aims to improve modifiable risks, in turn reducing subsequent morbidity and mortality. However, an evaluation with respect to mortality is lacking. Aims: Using linked population registries, we estimated the association of attending Heart Sch

Inflammation and chronic colonization of Haemophilus influenzae in sputum in COPD patients related to the degree of emphysema and bronchiectasis in high-resolution computed tomography

The presence of bacteria in the lower airways in COPD results in inflammation, further airway structural damage, and might lead to repeated exacerbations. We have previously shown that chronic colonization of Haemophilus influenzae during stable disease is related to increased inflammation, and we now aimed to relate previous findings of bacterial colonization and inflammation to the degree of rad

Donanemab in Early Symptomatic Alzheimer Disease : The TRAILBLAZER-ALZ 2 Randomized Clinical Trial

Importance: There are limited efficacious treatments for Alzheimer disease. Objective: To assess efficacy and adverse events of donanemab, an antibody designed to clear brain amyloid plaque. Design, Setting, and Participants: Multicenter (277 medical research centers/hospitals in 8 countries), randomized, double-blind, placebo-controlled, 18-month phase 3 trial that enrolled 1736 participants with

Measuring Semantic Distances between Software Artifacts to Consolidate Issues from the Development and the Field

Identifying and keeping track of different structural representations of functionally overlapping issues is important in order to keep a well maintained issue management corpus, establishing efficient and organized response ability to develop and code software patches repairing these issues and defects. This is normally achieved by manual, time-costly reviewing-processes by special teams put up to

The proposed Perform Achieve and Trade (PAT) scheme in India: A policy evaluation

Perform, Achieve and Trade (PAT) scheme, proposed in 2008,is the first of its kind energy efficiency trading scheme in India. PAT aims for improving the energy efficiency in the eight most energy intensive large scale industrial sectors, covering almost 54% of the total energy consumption in India, through certification of energy savings which can be traded. This thesis seeks to provide an early i

Using Artificial Intelligence for Assessment of Velopharyngeal Competence in Children Born With Cleft Palate With or Without Cleft Lip

ObjectiveDevelopment of an AI tool to assess velopharyngeal competence (VPC) in children with cleft palate, with/without cleft lip.DesignInnovation of an AI tool using retrospective audio recordings and assessments of VPC.SettingTwo datasets were used. The first, named the SR dataset, included data from follow-up visits to Skåne University Hospital, Sweden. The second, named the SC + IC dataset, w

Components of early outpatient palliative care consultation in patients with metastatic nonsmall cell lung cancer

BACKGROUND: Although palliative care consultation is recommended early in the course of oncology treatment, little evidence exists to guide the nature of this intervention. We describe a clinical practice of early palliative care consultation that improved quality of life, mood, and survival in a randomized clinical trial.METHODS: As part of a randomized trial of early palliative care versus stand

Pesticide exposure in farming and forestry and the risk of uveal melanoma

Since pesticides are disputed risk factors for uveal melanoma, we studied the association between occupational pesticide exposure and uveal melanoma risk in a case-control study from nine European countries. Incident cases of uveal melanoma and population as well as hospital controls were included and frequency-matched by country, 5-year age groups and sex. Self-reported exposure was quantified wi

Voice evaluation before and after laser excision vs. Radiotherapy of t1a glottic carcinoma

Quality of voice after treatment for T1A glottic squamous cell carcinoma was studied in two matched groups of males treated either with CO2 laser cordectomi (n = 18, mean age 65.2 years) or with full dose radiotherapy (n = 18, mean age 65.1 years). All patients had histologically verified invasive squamous cell carcinoma. Fifteen male patients (mean age 63.9 years) without laryngeal disorders were

Quality of life after switching to generic levetiracetam – A prospective comparative study

BackgroundImproved quality of life (QoL) is one of the most important objectives in the treatment of epilepsy. Recent prospective, clinical studies proved no significant differences between brand antiepileptic drugs (AEDs) and their generic equivalents in terms of seizure control, pharmacokinetics, or safety. In this study, we focused on possible changes in QoL and adverse events in connection wit

Structural effects of sprifermin in knee osteoarthritis : a post-hoc analysis on cartilage and non-cartilaginous tissue alterations in a randomized controlled trial

Background: A recent publication on efficacy of Sprifermin for knee osteoarthritis (OA) using quantitatively MRI-defined central medial tibio-femoral compartment cartilage thickness as the structural primary endpoint reported no statistically significant dose response. However, Sprifermin was associated with statistically significant, dose-dependent reductions in loss of total and lateral tibio-fe

Asthma in Swedish children conceived by in vitro fertilisation.

OBJECTIVES: To investigate a proposed association between in vitro fertilisation (IVF) and child asthma. DESIGN: The risk for asthma after IVF was estimated as ORs using Mantel-Haenszel analysis. SETTING: The Swedish Medical Birth Register. PATIENTS: Of the 2 628 728 children born in 1982-2007 and surviving the perinatal period, 31 918 were conceived by IVF. Presence of asthma was define

Blastocyst versus cleavage stage transfer in in vitro fertilization: differences in neonatal outcome?

OBJECTIVE: To compare neonatal outcome of blastocyst and cleavage stage embryo transfers after IVF. DESIGN: Register study. PATIENT(S): Treatments reported from all Swedish IVF clinics. INTERVENTION(S): None. SETTING: Births recorded in the Swedish Medical Birth Register after IVF performed, 2002-2006. MAIN OUTCOME MEASURE(S): Some neonatal characteristics were compared in 1,311 infants born after

Do women enrolled in PMTCT understand the recommendations : A case study from Kilimanjaro

Introduction: Prevention of mother-to-child transmission (PMTCT) remains a cornerstone of HIV prevention and control efforts. It is vital that the beneficiaries of PMTCT programs understand PMTCT recommendations, especially since their adherence to recommendations is key to successful PMTCT. There have been several major changes in PMTCT recommendations, and many women have encountered different r

Personalized breast cancer screening with selective addition of digital breast tomosynthesis through artificial intelligence

PURPOSE: Breast cancer screening is predominantly performed using digital mammography (DM), but digital breast tomosynthesis (DBT) has higher sensitivity. DBT demands more resources than DM, and it might be more feasible to reserve DBT for women with a clear benefit from the technique. We explore if artificial intelligence (AI) can select women who would benefit from DBT imaging.APPROACH: We used

Prevalence of musculoskeletal disorders and physiotherapy utilization in primary care - a registry-based study in Sweden

BACKGROUND: Previous research has identified a need for relevant evidence-based clinical guidelines in primary care physiotherapy. However, an essential first step is to identify the most prevalent diagnoses among patients seeking physiotherapy. Thus, this study aims to (I) identify the most prevalent musculoskeletal diagnoses and, (II) describe physiotherapy utilization and patient characteristic

From waste management to waste prevention

Closing implementation gaps through sustainable action nets This project deals with the principle formulated by the Swedish Environmental Protection Agency that sustainable waste policy should be oriented toward waste prevention and not only waste management. National authorities can steer through decisions and legislation, and introduce incitements and control mechanisms. But practical responsibi

https://www.ses.lu.se/fran-avfallshantering-till-avfallsforebyggande-0/waste-management-waste-prevention - 2026-06-01

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https://www.geology.lu.se/form/pollen-order-page - 2026-06-01