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Background Risk factors included in the cardiovascular (CHA2DS2‐VASc) score, currently used for atrial fibrillation (AF), may predispose to cardiovascular events whether or not AF is present. The aim was to explore the predictive role of CHA2DS2‐VASc score on cardiovascular outcomes in diabetic patients without AF. Methods We accessed individual data from 610 diabetic patients without AF at baseli
Fascineras du också av hjärnan och dess komplexitet men också av hur nya tekniker och den snabba utvecklingen inom bioteknologi kan öppna upp för helt nya behandlingar? Då kan vår forskning vara något för dig! Vårt fokus är på att utveckla avancerade terapier såsom cell- och genterapi för Parkinsons sjukdom. Vi arbetar också hårt för att hitta ett botemedel för en av de mest fruktansvärda sjukdomaAre you intrigued by the brain and its complexity, as well as by new technologies and the amazing developments in biotechnology? Then our research may be for you. Our main focus is on developing advanced therapeutical medical products (ATMPs), such as cell and gene therapy for Parkinson's disease. We are also working to treat one of the most devastating disorders of the human brain: glioblastomas,
Chronic myeloid leukemias and 5% to 20% of acute lymphoid leukemias are characterized by the Philadelphia chromosome, a reciprocal chromosomal translocation, t(9;22)(q34;q11), generating BCR-ABL and ABL-BCR fusion genes. Cytogenetic studies have recently shown a preferential involvement of the paternally derived chromosome 9 and the maternally derived chromosome 22 in this translocation, indicatin
The virological efficacy of a syringe/needle exchange program was evaluated in a cohort incidence study. Of 698 intravenous drug users (IVDUs) initially recruited, 15 (2.1%) were HIV-positive at baseline. Adequate follow-up was possible in 515 (74%) and showed no new cases of HIV infection during a median of 31 months. Most IVDUs had been previously exposed to HBV (anti-HBc-positive 70.1%) and HCV
Here you will find links to news sites, tips and guides for some of the largest channels in social media. Page shortcuts:FacebookInstagramLinkedInXYouTubeSnapchatTikTokBlueSkyImage sizesMany social media channels frequently change their recommended sizes for e.g. profile pictures, cover photos and feed images. Here you will find a guide updated in 2024:Guide on social media image sizes through mel
https://www.staff.lu.se/support-and-tools/communication-and-graphic-profile/social-media/tips-different-channels - 2026-10-07
It remains unknown whether human papillomaviruses (HPVs) or human herpesviruses (HHVs) in semen affect sperm DNA integrity. We investigated whether the presence of these viruses in semen was associated with an elevated sperm DNA fragmentation index. Semen from 76 sperm donors was examined by a PCR-based hybridization array that identifies all HHVs and 35 of the most common HPVs. Sperm DNA integrit
Popular Abstract in Swedish Astma och hösnuva (allergisk rinit) är två närbesläktade sjukdomar som båda har sin grund i en långdragen, kronisk inflammation i luftvägsslemhinnan. Vid både astma och hösnuva har slemhinnan en benägenhet att reagera kraftigare än normalt på retningar (s.k. hyperreaktivitet). Inflammationen och hyperreaktiviteten regleras av hundratals olika signalsubstanser (mediatoreMucosal inflammation and airway hyperreactivity are regulated by hundreds of different mediators. The recent discovery of gaseous mediators, produced and active within the airways, opens new possibilities for identification of therapeutic targets and ways to monitor airway inflammation. This thesis is focused on two such mediators, nitric oxide (NO) and carbon monoxide (CO) along with their role i
It has often been argued that the Earth is like an island in space and that its brittleness is most clearly reflected on small islands in the oceans. Easter Island, in particular, with its largely depleted resources, has been seen as a microcosmic warning about what could happen to our entire planet. However, the analogy of the Earth and islands with finite natural resources is not self-evident fr
It has often been argued that the Earth is like an island in space and that its brittleness is most clearly reflected on small islands in the oceans. Easter Island, in particular, with its largely depleted resources, has been seen as a microcosmic warning about what could happen to our entire planet. However, the analogy of the Earth and islands with finite natural resources is not self-evident fr
The functional role of the GGN repeat in the human androgen receptor gene is unknown, although mutations in this region have been found in patients with inter-sex conditions. We have investigated the prevalence of GGN mutations in the androgen receptor in the Swedish population and their relation to male reproductive function. A physical examination and semen analysis was carried out in 223 men un
Här hittar du länkar till nyhetssidor, tips och guider för några av de största kanalerna inom sociala medier. Genvägar på sidan:BildstorlekarSkydda ditt kontoFacebookInstagramLinkedInXYoutubeSnapchatTikTokBlueSkySamtliga länkar nedan leder till kanalernas egna sidor, varav flera är på engelska.BildstorlekarMånga sociala medier ändrar sina rekommenderade storlekar för exempelvis profilbilder, omsla
Background. Shipment of pancreata between distant centers is frequently associated with prolonged cold ischemia time (CIT) that leads to poorer outcomes for islet transplantation. Clinical pilot trials have indicated that oxygenation of explanted human pancreata utilizing the two-layer method (TLM) allows the use of marginal donor pancreata for islet transplantation. The present study aimed to cla
OBJECTIVES: Infectious agents like parvovirus have been implicated as exogenous factors that could trigger onset of systemic lupus erythematosus (SLE). A number of case reports describing a SLE-like presentation of acute human parvovirus B19 infection have been published, but no systematic investigation of the actual seroprevalence in epidemiologically defined SLE populations has previously been r
The possible implication of the gasotransmitters NO and CO for the development of diabetes remains unresolved. Our previous investigations in rodents suggested NO being inhibitory, and CO stimulatory, to glucose-stimulated insulin secretion (GSIS). Here we studied the possible role of these gasotransmitters in both murine and human type 2 diabetes (T2D) by mapping the expression pattern of neural
Animal research show that a novel exploration task performed shortly before a learning episode can strengthen hippocampal memory consolidation through behavioural tagging mechanisms. The aim of the present study was to conceptually translate behavioural tagging results to humans using a novel exploration task in virtual reality. Mimicking conditions for animal research, sixty participants underwen
Calcitonin gene-related peptide (CGRP) and nitric oxide (NO) are two molecules shown to have a role in migraine pathophysiology. Our objective was to test the hypothesis that migraine subjects are particularly sensitive to these signal molecules. The cutaneous microvascular responses to endothelial and non-endothelial dependent dilators were tested using laser Doppler flowmetry in combination with
Introduction How the burden of disease varies during different phases after floods and after storms is essential in order to guide a medical response, but it has not been well-described. The objective of this review was to elucidate the health problems following flood and storm disasters.Methods: A literature search of the databases Medline (US National Library of Medicine, National Institutes of
The pancreas is particularly sensitive to acute cellular stress, but this has been difficult to evaluate using light microscopy. Pancreatic ischaemia associated with deceased organ donation negatively impacts whole-organ and isolated-islet transplantation outcomes. Post-mortem changes have also hampered accurate interpretation of ante-mortem pancreatic pathology. A rigorous histological scoring sy
