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Five parkinsonian patients were transplanted bilaterally into the putamen and caudate nucleus with human embryonic mesencephalic tissue from between seven and nine donors. To increase graft survival, the lipid peroxidation inhibitor tirilazad mesylate was administered to the tissue before implantation and intravenously to the patients for 3 days thereafter. During the second postoperative year, th

INTRODUCTION: The aim of this study was to compare different methods to predict acute coronary syndrome (ACS) using only data from a single electrocardiogram (ECG) in the emergency department (ED). METHOD: We compared the ACS prediction abilities of classical ECG criteria, human expert ECG interpretation, a logistic regression model and an artificial neural network ensemble (ANN). The ED ECG and d

Introduction. The aetiology and pathogenesis of ulcerative colitis (UC) are essentially unknown. Galectins are carbohydrate-binding lectins involved in a large number of physiological and pathophysiological processes. Little is known about the role of galectins in human UC. In this immunohistochemical exploratory study, both epithelial and inflammatory cell galectin expression were studied in pati

Objective: To identify the consequences of an anterior cruciate ligament (ACL) tear in a cohort of male soccer players 14 years after the initial injury with respect to radiographic knee osteoarthritis and patient relevant outcomes. Methods: Of 219 male soccer players with an ACL injury in 1986, 205 (94%) were available for follow up after 14 years; 75% of the cohort (154/205) answered mailed que

Abstract in Norwegian Bakgrunn. Fallulykker er et viktig helseproblem hos eldre. Både balansetesting og registrering av egenrapportert funksjon kan være måter å forutse fremtidige ulykker på. Materiale og metode. I en kohortstudie ble egenrapportert gangfunksjon kartlagt hos 307 tilfeldig utvalgte hjemmeboende kvinner 75 år og eldre. Kvinnene gjennomgikk også testing av balanse og gangfunksjon, oBACKGROUND: Falls represent an important health problem among the elderly. Balance testing as well as registration of self-reported balance problems may be appropriate in order to predict the risk of future falls. MATERIALS AND METHODS: Self-reported walking was assessed in 307 randomly selected women 75 years or older living at home. The women underwent testing of gait and balance and were follow

Six patients with Parkinson's disease were followed for 10 to 72 months after human embryonic mesencephalic tissue from four to seven donors was grafted unilaterally into the putamen (4 patients) or putamen plus caudate (2 patients). After 8 to 12 months, positron emission tomography showed a 68% increase of 6-L-[18F]-fluorodopa uptake in the grafted putamen, no change in the grafted caudate, and

We investigated if low level laser therapy (LLLT) of the joint capsule can reduce pain in chronic joint disorders. A literature search identified 88 randomised controlled trials, of which 20 trials included patients with chronic joint disorders. Six trials were excluded for not irradiating the joint capsule. Three trials used doses lower than a dose range nominated a priori for reducing inflammati

Objective . To assess self-reported activity limitations in a clinical sample of stroke patients and to identify their association with prevalence, severity and impact on daily life of lower urinary tract symptoms (LUTS). Material and methods . A cross-sectional, clinical survey was initiated whereby stroke patients were invited to complete four activity limitations measurements: Barthel Index, mo

The 39-item Parkinson's disease questionnaire (PDQ-39) is the most widely used patient-reported rating scale in Parkinson's disease (PD). However, recent studies have questioned its validity and it is unclear what scores represent. This study explored the possibility of regrouping PDQ-39 items into scales representing the International Classification of Functioning, Disability, and Health (ICF) co

I denna rapport har brandskyddet i kv. Niagara i Malmö undersökts och utvärderats. Syftet med rapporten har varit att bedöma personsäkerheten i byggnaden kv. Niagara i händelse av brand. Detta har gjorts genom att utvärdera det befintliga brandskyddet och utrymningsmöjligheter. Målet har sedan varit att fastställa om det befintliga brandskyddet är skäligt med hänseende på personsäkerhet, med fokus

This thesis examines the discourse concerning the consent-based rape law reform in Sweden and Denmark. Sweden implemented the consent-based rape law July 2018 and has since been evaluating the law while the current Danish government promised that the law will change to a consent-based law. I focus on eight Danish articles and eight Swedish news articles in which the consent-based rape law reform i

More reliable and faster prediction methods are needed to interpret enormous amounts of data generated by sequencing and genome projects. We have developed a new computational tool, PON-P2, for classification of amino acid substitutions in human proteins. The method is a machine learning-based classifier and groups the variants into pathogenic, neutral and unknown classes, on the basis of random f

By breeding TRAMP mice with S100A9 knock-out (S100A9(-/-)) animals and scoring the appearance of palpable tumors we observed a delayed tumor growth in animals devoid of S100A9 expression. CD11b(+) S100A9 expressing cells were not observed in normal prostate tissue from control C57BL/6 mice but were readily detected in TRAMP prostate tumors. Also, S100A9 expression was observed in association with

DNA copy number aberrations (CNAs) are a hallmark of cancer genomes. However, little is known about how such changes affect global gene expression. We develop a modeling framework, EPoC (Endogenous Perturbation analysis of Cancer), to (1) detect disease-driving CNAs and their effect on target mRNA expression, and to (2) stratify cancer patients into long-and short-term survivors. Our method constr

Objective: Zea m1 is one of the most common aeroallergens, causing allergy. This pollen allergen, present in maize, is responsible for type I hypersensitivity reaction. Despite having available X ray crystal structure of this pollen allergen, no definite vaccine has been developed for allergic disorder in humans. Method: In our present study, an epitope-based peptide vaccine against Zea m 1 pollen

Background: The Hip disability and Osteoarthritis Outcome Score (HOOS) is a self-administered hip-specific questionnaire intended to evaluate symptoms and functional limitations, and it is commonly used to evaluate interventions in individuals with hip dysfunction or hip osteoarthritis. The HOOS consists of 43 questions in five subscales: Pain, Symptoms, Function in daily living, Function in sport

Purpose: To evaluate the association between a previously published 313 variant–based breast cancer (BC) polygenic risk score (PRS313) and contralateral breast cancer (CBC) risk, in BRCA1 and BRCA2 pathogenic variant heterozygotes. Methods: We included women of European ancestry with a prevalent first primary invasive BC (BRCA1 = 6,591 with 1,402 prevalent CBC cases; BRCA2 = 4,208 with 647 prevale

Objective: To describe and compare hip and groin strength and function of male ice hockey players over one season in players with and without hip and groin problems in the previous season. Design: Prospective cohort study. Setting: Swedish male ice hockey. Participants: We followed 193 players from 10 teams during the 2017/2018 season. Main outcome measures: Hip adduction and abduction strength, 5

IIIEE Alumni Network Conference, May 18-20, 2017 This year’s conference is part of Lund University’s 350 years celebrations, takes place during ‘sustainability week’ in Lund, coincides with the LUMES alumni conference, and is in a new, hopefully beautiful, time of the year. Many reasons to come to Lund! CLICK HERE TO REGISTER Wednesday, May 17 18:00 Drinks and registration for early arrivers Locat

https://www.iiiee.lu.se/sites/iiiee.lu.se/files/iiieenetwork2017_detailed_programme.pdf - 2026-05-29

PowerPoint-presentation Communicate your societal impact - Guide for producing impact cases DANIEL GUSTAFSSON, PHD, RESEARCH COORDINATOR, DEPARTMENT OF HUMAN GEOGRAPHY 2024 Conditions for using the guide • The following guide is intended to be an aid for researchers who want to study, illustrate and communicate the societal impact of their research in the form of so-called impact cases (also calle

https://www.sam.lu.se/en/internal/sites/sam.lu.se.en.internal/files/2025-03/guide-societal-impact.pdf - 2026-05-29