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International research collaboration stands at a pivotal juncture, shaped by enduring structural inequalities between high-, middle-, and low-income countries and challenged by a trend of withdrawal from international collaboration. These asymmetries can create a misalignment between global scientific progress and the capacity to address pressing societal crises, which often disproportionately aff
Diabetes is a chronic disease that affects lots of people all around the world. It greatly impacts the health of those with it and places many demands on healthcare services. Early detection of diabetes can significantly improve treatment outcomes, lower the chances of future health issues, and help patients to have a better healthier life. In this study, I evaluated the reproducibility of the per
Atherosclerotic plaques with a low content of connective tissue proteins are believed to have an increased risk of rupture and to give rise to clinical events. The aim of the present study was to investigate if the content of elastin, collagen and of the matrix metalloproteinase (MMP) -1, -3, -9 and -12 in plaques removed at surgery can be associated with the occurrence of ipsilateral symptoms.
This study explores the influence of long-range intra-protein electrostatic interactions on the conformation of calmodulin in solution. Ensemble Förster resonance energy transfer (FRET) is measured for calmodulin with a fluorophore pair incorporated specifically with a donor at residue 17 and an acceptor at position 117. This construct was generated by a combination of solid phase peptide synthesi
Background. It is well known that portacaval shunting ultimately leads to a decrease in liver volume and hepatic function, but the mechanism is uncertain. The aim of the present study was to evaluate the effect of portacaval shunting (PCS) upon the morphological changes that occur in the liver in rats after port caval. anastomosis. Materials and methods. Sixty-six male rats underwent either PCS (n
Metabolomics is a rapidly growing research field. It aims for quantification of all the metabolites in a biological sample such as plasma, saliva, cerebrospinal fluid or cells. Because the metabolite levels in a biological sample are the end result of the regulatory processes in cells, metabolomics is a very powerful approach for characterisation of phenotypes. Metabolomics has been used to find d
Power mechanisms and structures can shape adaptation outcomes, the measures adopted, and who is identified as requiring adaptation support. But to what extent does research recognise such power-adaptation linkages? Based on a systematic literature review, we enquire if and how the framing of power matters for climate change adaptation research and what the implications may be for practice. Our enq
Recent years have seen an explosion in social media in our everyday lives, and a corresponding increase in social media research in IS. As social media researchers, we are intrigued by the problem of virtuality and context in social media research, and how we might apply reflexive research principles to such settings. In social media, the absence of a setting's real physical boundaries (to a large
Roundtable presentation for: The Orient There and Back Again. Multidisciplinary Reflections on MENA Research and Sweden 1974-2024 (roundtable organised by Annika Rabo). Chair: Rouzbeh Parsi (Swedish Institute of International Affairs)Participants: Marianne Boqvist (Folke Bernadotte Academy), Torsten Janson (Lund University), Pernilla Myrne (University of Gothenburg), Annika Rabo (Stockholm Univers
Kandidatuppsatsen undersöker effekterna av buzzwords inom informatikforskning; den granskar hur dessa termer formar forskningsagendor, metoder och gemenskapsidentiteter genom Social Identity Theory. Studien använder en kvalitativ forskningsansats där data samlades in genom intervjuer från medvetet utvalda akademiker inom informatikområdet och analyserades tematiskt, vilket ledde till slutsatsen om
Concerns have been raised about the marketization of science through the prevailing funding regime. However, the present article will discuss how it comes that the potentially marketable stem cell science is not more commercialized than what is currently the case. We approach this question by analysing discursive pluralism in defining the value of stem cells within a grant allocation process. More
Purpose: The purpose of this paper is to contribute to a more complete understanding of logistics preparedness. By comparing extant research in preparedness and logistics with findings from empirical analysis of secondary data, the authors develop a definition of and framework for logistics preparedness, along with suggestions for future research agenda. Design/methodology/approach: The authors li
Located on the Pacific Ring of Fire, the extended Japanese archipelago is among the most geologically hazardous zones for human habitation located anywhere on the planet. Despite these threats and challenges, Japan has supported a series of unique cultures and societies that have evolved and changed over many millennia. The major existential risks include relentless volcanic eruptions, earthquakes
Alveoli are sac-like structures in the distal lung specialised for gaseous exchange. Alveolar epithelium facilitates efficient respiration through a thin and robust arrangement of type-I (AT1) and type-II (AT2) pneumocytes, supported by tight junctions and surfactant-rich alveolar lining fluid. Chronic diseases like pulmonary fibrosis, asthma, and sarcoidosis compromise alveolar integrity, resulti
BackgroundWomen are at a greater risk of a major adverse cardiovascular event (MACE) after percutaneous coronary intervention than men. A history of preterm delivery is a female-specific risk factor for coronary artery disease, but its relevance in the treatment of coronary artery disease is unknown.ObjectivesThe purpose of this study was to analyze the association between a history of preterm del
This paper analyses ethical issues in forensic psychiatric research on mentally disordered offenders, especially those detained in the psychiatric treatment system. The idea of a 'dual role' dilemma afflicting forensic psychiatry is more complicated than acknowledged. Our suggestion acknowledges the good of criminal law and crime prevention as a part that should be balanced against familiar resear
The cost of treating cardiovascular disease (CVD) and diabetes is enormous and is set to rise in the coming years. Physical inactivity and sedentary behaviors are major risk factors for these diseases and are estimated to account for several million global deaths annually. Lifestyle interventions, particularly those aimed at enhancing physical activity levels, have a substantial favorable impact o
BACKGROUND AND OBJECTIVES: Human genetic studies support a key role of interleukin-6 (IL-6) in the pathogenesis of ischemic stroke. Still, there are only limited data from observational studies exploring circulating IL-6 levels as a risk factor for ischemic stroke. Here, we set out to perform a systematic review and meta-analysis of aggregate data on cohort studies to determine the magnitude and s
