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Lumen diameter, distension and intima-media thickness (IMT) in human arteries are important parameters in cardiovascular research. The signal reflected from the arterial wall strongly depends on the ultrasound scanner and settings. The signal also varies with age and health of the subject. A general method insensitive with respect to the subject and the scanner would be of great help. We have deve
INTRODUCTION: Thyrotoxicosis is often considered to be the most difficult thyroid operation because of the high vascularisation and the risk of bleeding. The conventional haemostatic technique in thyroidectomy today include knot tying and electrocoagulation. The introduction of the harmonic scalpel (HS) has led to further research if the use of the HS has any benefits in thyroid surgery. To our kn
It is well known that WLAN based on the IEEE 802.11 standard suffers from interference and scalability problems due to a limited number of non-overlapping channels. In order to mitigate the interference problem, channel assignment algorithms have been a popular research topic in recent years. It has been shown that such algorithms can greatly reduce the interference among wireless access points. H
Despite its post-Soviet history, Azerbaijan is an under-investigated country in academic research - compared with the other former constituencies, such as the Baltic countries or Russia, of the USSR-and gender questions of the contemporary Azerbaijani society are even less touched on. Within the current context of the post-"Arab Spring" era of mediatized connectivity and collective political engag
Dinoflagellates are a group of protists whose genome is unique among eukaryotes in terms of base composition, chromosomal structure and gene expression. Even after decades of research, the structure and behavior of their amazing chromosomes—which without nucleosomes exist in a liquid crystalline state—are still poorly understood. We used fl
In this study, a surface plasmon resonance (SPR) biosensor was developed for the detection and quantification of a secreted bacterial factor (RoxP) from skin. A molecular imprinting method was used for the preparation of sensor chips and five different monomer-cross-linker compositions were evaluated for sensitivity, selectivity, affinity, and kinetic measurements. The most promising molecularly i
The communicative role of nonlinear vocal phenomena remains poorly understood since they are difficult to manipulate or even measure with conventional tools. In this study parametric voice synthesis was employed to add pitch jumps, subharmonics/sidebands, and chaos to synthetic human nonverbal vocalizations. In Experiment 1 (86 participants, 144 sounds), chaos was associated with lower valence, an
This research investigates the behavior of intrinsically disordered proteins (IDPs) in solution, especially the self-associating saliva protein Statherin, by a combined computational and experimental approach. For the computational part, a bead necklace model previously parameterised for Histatin 5 was used. This model was shown to be applicable to a range of monomeric intrinsically disordered pro
Cracks in concrete structures can have a negative impact on durability and aesthetic appearance. It is therefore important to estimate crack widths before construction, and to use suitable reinforcement amounts to limit crack widths. Crack widths are however hard to predict in restrained structures, as cracking reduces the stiffness, which in turn reduces the restraint and thereby the amount of cr
Året är 2053 och den svenska regeringen har just invigt museet FOSSIL och dess första utställning ’Carbon Ruins’. År 2045 uppnådde Sverige nettonollutsläpp av växthusgaser, och blev därmed det första landet i världen att lämna den fossila tidsåldern (1849 - 2049). Två hundra år som förde med sig en otrolig välståndsökning, men också oljerelaterade konflikter och en klimatkatastrof som allvarligt hIt is 2053. The Swedish government has just opened its landmark museum FOSSIL with its first exhibition Carbon Ruins. The exhibition and its grand opening is a celebration of the fact that global net-zero emissions of carbon dioxide were reached in 2050. Sweden, in line with its 2017 targets, reached net-zero emissions of greenhouse gases already in 2045, being the first country in the world to st
A fraction from human milk containing spf-multimer alpha-lactalbumin (MAL) induces apoptosis in tumor cells and immature cells but spares mature cells. The mechanism of apoptosis induction and the molecular basis for the difference in susceptibility between tumor cells and healthy cells have not been defined. In this study we examined the interaction of MAL with different cellular compartments, us
The purpose of this study was to investigate the adhesion properties and tissue reactions in an in vitro model of nanofabricated membranes emulating the vitreous cortex. Electrospinning was performed for either 5, 10 or 15 min to create various thicknesses of poly(ε-caprolactone) (PCL) fibre mats on a poly(glycerol-co-sebacic acid) (PGS) surface. These were fused with adult porcine retinal explant
The p16 (CDKN2/MTS1/INK4a) malignant melanoma susceptibility gene was analyzed in 10 melanoma kindreds from southern Sweden using single-stranded conformation polymorphism analysis of all three exons and flanking intron regions followed by sequence analysis. A novel germline mutation, constituting an in-frame 3-bp duplication at nucleotide 332 in exon 2, was identified in two families (Lund M2 and
Airborne particulate matter emitted from motor vehicle brakes is a contributor to urban air quality. Therefore, a method to rank brake pairs (pads and rotors) with respect to their particle emission factors in a reliable way is needed to develop a low-emission disc brake. A novel inertial disc brake dynamometer designed for brake particle emission studies, a modified SAE J 2707 cycle, an electrica
Background: Breast cancer (BC) and related treatment are associated with the risk of developing a wide range of persistent disabling impairments. Despite extensive research in the field and an enhanced focus on BC rehabilitation, up to 34-43% of these patients are at risk of developing chronic distress. In addition, it is known that these patients repeatedly report unmet needs, which are strongly
BackgroundMajor depressive disorder (MDD) is associated with increased allostatic load (AL; a measure of physiological costs of repeated/chronic stress-responding) and metabolic dysregulation (MetD; a measure of metabolic health and precursor to many medical illnesses). Though AL and MetD are associated with poor somatic health outcomes, little is known regarding their relationship with antidepres
Road tunnel fires are non-recurrent events which have led the researchers to investigate on the best risk analysis methodology. At the moment, the European Directive 2004/54/EC on minimum safety requirements for tunnels in the Trans-European road network gives only general statements. Consequently, practitioners have often difficulties to define the best way to ensure the desired safety conditions
