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OBJECTIVES: Combination chemotherapy regimens have shown promising results in patients with metastatic colorectal cancer. However, only very few studies have studied the effect of palliative chemotherapy in peritoneal carcinomatosis (PC) and no data are present incorporating biological therapies in the treatment of PC in colorectal cancer.METHODS: By means of merging with the regional Eindhoven Ca
To improve resistance to upcoming vulnerabilities to climate change and cope with rising food demand smallholders in Sub-Saharan Africa need to upgrade their local food systems. Upgrading strategies (UPS) within existing food value chains have the potential to secure food at the local to regional level. In this paper, we determined the roles of actors and their interlinkages and motivations in UPS
Resilience and gender have become new buzzwords for expressing renewal in peacebuilding. This article unpacks the gender-resilience nexus in theory and analyses global trends and variation in peacebuilding policy and practice. It advances an analytical framework based on three central pillars of peacebuilding: process, outcome, and expertise. A comprehensive analysis of 49 international peacebuild
The market for ready-to eat vegetables is increasing, but unfortunately so do the numbers of food-borne illness outbreaks related to these products. A previous study has identified bacterial strains suitable for biocontrol of leafy green vegetables to reduce the exposure to pathogens in these products. As a tentative safety evaluation, five selected strains (Rhodococcus cerastii MR5x, Bacillus coa
Background: While HPV vaccination uptake in Sweden is quite high, at around 80%, vaccine hesitancy remains an issue in countries throughout Europe. The latter can be related to a contemporary context of increased contestation of expert knowledge and of a large share of information on health-related issues including vaccination today being sought via the internet. Still, there is a paucity of recen
The article discusses the language of border externalisation processes by examining the knowledge that stands as the basis of the EU–Turkey deal and reports on its implementation, placing them in the context of the transformation of the EU border regime. It is the result of a study addressing the language and key concepts that organise border externalisation and its geographic and biopolitical epi
Accurate prediction on the pressurized discharge performance is significant to the safety operation of cryogenic propellant system. In the present study, a two-dimensional numerical model is established to simulate the fuel outflow with high-temperature gas injection. Both the environmental heat invasion and interfacial phase change are detailedly considered. The volume of fluid method is used to
Sleep duration is emerging as an important modifiable risk factor for morbidity and mortality. We assessed the association between sleep duration and cancer incidence and mortality among Japanese adults using data from six population-based cohorts with 271 694 participants. During a total follow-up period of about 5.9 million person-years, we identified 40 751 incident cancer cases and 18 323 canc
The combination of a reducible transition metal oxide and a noble metal such as Pt often leads to active low-temperature catalysts for the preferential oxidation of CO in excess H2 gas (PROX reaction). While CO oxidation has been investigated for such systems in model studies, the added influence of hydrogen gas, representative of PROX, remains less explored. Herein, we use ambient pressure scanni
The present paper describes a quasi-experimental research presenting a workplace training program aimed at helping managers to be more supportive of their employees' autonomy. Drawing on self-determination theory, we built a pre/post questionnaire design measuring perceived autonomy support, need satisfaction, need frustration, autonomous motivation, controlled motivation, work engagement and job
he case that constitutes the subject for this paper is a voluntourism project organized in the Faroe Islands that has gained worldwide attention. Unskilled volunteers were called to perform maintenance works while popular hiking trails remained closed for regular tourists. The idea turned into a successful marketing campaign for the Faroe Islands. Our study is anchored in theories on tourism desti
Objective: Differences in outcome after radical prostatectomy for prostate cancer can partly be explained by intersurgeon differences, where degree of experience is one important aspect. This study aims to define the learning curve of robot-assisted laparoscopic prostatectomy (RALP) regarding oncological and functional outcomes. Materials and methods: Out of 4003 enrolled patients in the LAPPRO tr
Many surface science experiments within heterogeneous catalysis are now conducted in realistic conditions at higher pressures. At these pressures, localized gas conditions will form throughout the reactor. Understanding these gas conditions and their interaction with the catalyst surface at relevant time scales and with spatial resolution is important. To address this issue, we use a combination o
Dominant policy approaches have failed to generate action at anywhere near the rate, scale or depth needed to avert climate change and environmental disaster. In particular, they fail to address the need for a fundamental cultural transformation, which involves a collective shift in mindsets (values, beliefs, worldviews and associated inner human capacities). Whilst scholars and practitioners are
Background: Patients with oesophageal and gastric cancer face a poor prognosis and multiple symptoms and problems that negatively affect their quality of life. In view of the prognosis and extensive illness burden, an early palliative care approach is of importance.Aim: The overall aim of this thesis was to describe and compare symptoms, problems and care needs in relation to the initial treatment
This thesis examines the effects of pseudo and quasi-random number generators on the accuracy and efficiency of Monte Carlo Integration in the case of the multivariate normal distribution. The study compares the performance of the Mersenne Twister (a pseudo-random number generator) with Sobol and Halton sequences (quasi-random number generators). By evaluating these generators across different dim
Inom fastighetsbildning är lämplighetskravet ett centralt begrepp som lägger grunden för alla fastighetsbildningar och fastighetsregleringar som genomförs. Grundpelarna som bygger upp lämplighetsprövningen är belägenhet, omfång, och övriga förutsättningar. Trots detta finns det förhållandevis lite fasta gränser eller riktmärken att hålla sig till, vilket delvis är meningen, men det kan göra lämpliA property’s suitability is a central part of the Swedish Property Formation Act. It states that any creation or reformation of property must be suitable in regards to range, situation and other circumstances. Despite this, the actual requirements as to what is suitable are very vague, which in part is on purpose to account for changing politics and research. This master’s thesis aims to clarify t
Following the continual degradation of climate, the issue of climate change has increasingly been integrated in world politics. The European Union has itself implemented climate policies to adverse the tendency. However, the union has also given rise to the principle of free movement, a concept tightly connected to the EU’s carbon intensive transport sector. Research has shown the need for the EU
This paper examines how negative supply shocks in the form of the oil price and disruptions in the global value chains have affected Swedish consumer price inflation in two periods: 1998Q1- 2022Q3 and 1998Q1-2019Q4. The results from the time series regressions supports the two hypotheses that both the oil price and disruptions in the global value chains have a positive impact on consumer price
