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Popular Abstract in Swedish Enzymer har använts av människan sedan urminnes tider. Mycket tidigt lärde man sig att jäst kunde användas för att jäsa bröd och för framställning av vin och öl. Det är då just enzymerna som finns i jästsvampar som utnyttjas. I lite mera modern tid så fick enzymer ett stort användningsområde i tvättmedel på grund av deras unika förmåga att bryta ner fett och smuts vid gThe use of enzymes for synthetic applications is an area of increasing interest. Enzymes have been pointed out to be an environmentally friendly alternative to existing chemical methods, as well as making completely new synthetic routes possible. Over the last decades, much focus has been put on the enzyme group oxidoreductases, which can selectively introduce oxygen and hydrogen into molecules. T

The gold-bracteates from the migration period are circular medallion like objects with a diameter of about 5 cm. The production began at approximately AD 450 and came to an end at about AD 550. Thus the bracteates were in use for a period of a hundred years. This dissertation focuses on the iconography of the so called C-bracteates. The motifs of the C-bracteates depicts a human head over four leg

Popular Abstract in Swedish Hållbara matvanor - från jord till bord I Sverige äter vi i genomsnitt 800 kg mat per person och år. Vad och hur mycket vi väljer att stoppar i oss har stor betydelse både för planetens och vårt eget välmående. Den här avhandlingen handlar om hur våra val av livsmedel i den dagliga kosten påverkar miljön och hälsan. Vilken typ av livsmedel vi väljer att äta och dessa Food production and consumption are key drivers of environmental pressures and are essential factors in the promotion and maintenance of health. Production of food occupies more than one third of global land areas and is estimated to be responsible for some 30% of global greenhouse gas emissions. At the same time, we live in a world where nearly one billion people go hungry and even more people su

Abstract Aim: The Redesigning Daily Occupations programme (ReDO) is a Swedish work rehabilitation programme for women on sick leave due to stress-related disorders. The aim of the study was to investigate the participants' perceptions of taking part in the work rehabilitation programme. Methods: Seven of the 38 women who completed ReDO were interviewed during and after the programme. The interview

Purpose – This paper seeks to investigate the role of leadership styles in the implementation of evidence-based treatment methods (EBP) for drug abuse and criminal behaviour. Design/methodology/approach – The paper employs a triangulation approach through mail questionnaires to 112 treatment personnel (49 per cent response rate), interviews with 65 employees and managers, observations and feedbac

Background: Black and white pain drawings were introduced as a proposed means to identify patients, presenting with low back pain, who demonstrated functional overlay upon neurological testing. The use of color may enhance the usefulness of such pain drawings, but has not been described for adult patients. Aims: To retrospectively explore the use of colored pain drawings in patients with neck, low

Parkinson’s disease is predominantly a dopamine deficiency syndrome, which is produced in the brain by the loss of cells located in a small area in the ventral midbrain called the substantia nigra. Complete unilateral dopamine lesions, based on the administration of toxic substances (ie, 6-hydroxy-dopamine in rats and 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine in mice and primates) have been ext

The detection of the formyl radical (HCO) is of great interest in the field of combustion research since it can provide information about the local heat release (HR) rate which is a key parameter in the understanding of combustion processes. Unfortunately, due to the low signal level, HCO planar laser-induced fluorescence (PLTF) has so far not been applicable for single-shot imaging, which is nece

Rating scales are increasingly the primary outcome measures in clinical trials. However, clinically meaningful interpretation of such outcomes requires that the scales used satisfy basic requirements (scaling assumptions) within the data. These are rarely tested. The SF-36 is the most widely used patient-reported rating scale. Its scaling assumptions have been challenged in neurological disorders

In the wake of preventive thinking, attention has turned towards a life cycle perspective of products. Businesses can no longer ignore the environmental impacts of the products outside the borders of their own facilities. Consequently companies are now extending their environmental considerations beyond their internal production to include the environmental performance of their suppliers and suppl

Genome-wide association studies have identified common variants that only partially explain the genetic risk for type 2 diabetes (T2D). Using genome-wide association data from 1,376 French individuals, we identified 16,360 SNPs nominally associated with T2D and studied these SNPs in an independent sample of 4,977 French individuals. We then selected the 28 best hits for replication in 7,698 Danish

The classical pathway of complement is crucial to the immune system, but it also contributes to inflammatory diseases when dys-regulated. Binding of the C1 complex to ligands activates the pathway by inducing autoactivation of associated C1r, after which C1r activates C1s. C1s cleaves complement component C4 and then C2 to cause full activation of the system. The interaction between C1s and C4 inv

We carried out a multistage genome-wide association study of type 2 diabetes mellitus in Japanese individuals, with a total of 1,612 cases and 1,424 controls and 100,000 SNPs. The most significant association was obtained with SNPs in KCNQ1, and dense mapping within the gene revealed that rs2237892 in intron 15 showed the lowest P value (6.7 x 10(-13), odds ratio (OR) = 1.49). The association of K

The androgen receptor is a key transcription factor contributing to the development of all stages of prostate cancer (PCa). In addition, other transcription factors have been associated with poor prognosis in PCa, amongst which c-Myc (MYC) is a well-established oncogene in many other cancers. We have previously reported that the AR promotes glycolysis and anabolic metabolism; many of these metabol

Osteoarthritis (OA) of the knee can be defined as primary (non-traumatic) or secondary (post-traumatic). Both non-traumatic OA and post-traumatic OA have been described predominantly in the medial compartment of the knee. The objective of this study was to compare the location of structural radiographic changes in non-traumatic OA and post-traumatic OA. A non-traumatic cohort, consisting of 155 pa

Abstract The aim of this thesis was to perform health economic analyses of lifestyle intervention for people at a high risk of cardiovascular diseases (CVDs) and type 2 diabetes mellitus (T2DM). The results can help decision-makers to make informed decisions over implementing lifestyle intervention, taking several dilemmas into consideration. Paper I provides evidence on the cost-effectiveness of