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In this grounded theory study, the authors interviewed caregivers andpatients in end-of-life cancer care and found Balancing to be a fundamentalprocess explaining the problem-solving strategies of most participants and offering a comprehensive perspective on both health care in general and end-of-life cancer care in particular. Balancing stages wereWeighing— sensing needs and wishes signaled by pa

The mechanisms of protein folding and aggregation are investigated by computer simulations of all-atom and reduced models with sequence-based potentials. A quasi local Monte Carlo update is developed in order to efficiently sample proteins in the folded phase. A small helical protein, the B-domain of staphylococcal protein A, is studied using a reduced model. In the thermodynamically favoured topo

In the developed countries the public expect society to be prepared for, and step in, if something out of the ordinary happens. This public pressure appears to have increased the demand for crisis preparedness planning. In crisis management the local authority serves as the first line of defence and will more or less always be involved in responding to crises. It is therefore important to study ho

Purpose of this paper The purpose of this paper is to present a comparative case study of the procedures and guiding principles in the packaging selection practice of two international companies. Design/methodology/approach A qualitative case study with an inductive approach was conducted. The data was collected through semi-structured interviews, documentation, and field visits. Findings Th

In order to study the effect of different intensities of anti-vitamin K treatment on coagulation parameters, 23 patients with venous thromboembolism were given, after the initial treatment period, warfarin at doses giving an International Normalised Ratio of 1.3-2.0 for 4 weeks, and of 1.1-1.3 for another 4 weeks. Blood samples were taken at the end of each of these periods and 4 weeks after the e

It is well established that the mechanical environment modulates tissue differentiation, and a number of mechanoregulatory theories for describing the process have been proposed. In this study, simulations of an in vivo bone chamber experiment were performed that allowed direct comparison with experimental data. A mechanoregulation theory for mesenchymal stem cell differentiation based on a combin

The objective of this work is to compare the adherence to therapy of patients receiving etanercept and infliximab during first tumour necrosis factor (TNF)-blocking treatment course in rheumatoid arthritis. Special emphasis is placed on potential predictors for treatment termination and the impact of concomitant methotrexate (MTX) or other disease-modifying antirheumatic drugs (DMARDs). Patients (

Background: Thrombocytopenia is correlated to hemorrhagic complications in patients with low molecular weight heparin (LMWH) thromboprophylaxis. Aims: The aims of our study were to investigate an experimentally induced in vitro thrombocytopenia and then adding 2 types of LMWHs in vitro. Our hypothesis was that a platelet depleted whole blood sample

Safety, perceived and real, is essential for the attractiveness of urban environments (Avraham & Ketter, 2008, Coaffee & van Ham, 2008, Avraham, 2009). A high degree of perceived safety of a place plays a large role in attracting retail businesses, personnel, and customers. However, perceived safety is not an isolated issue, but related to many aspects, such as the planning of city space,

BACKGROUND: Healthcare organisations are in constant need of improvement and change. Nudging has been proposed as a strategy to affect people's choices and has been used to affect patients' behaviour in healthcare settings. However, little is known about how nudging is being interpreted and applied to change the behaviour of healthcare professionals (HCPs). The objective of this review is to ident

Society is highly dependent on services such as electricity, communication, and transportation. Furthermore, the critical infrastructures (CIs) that provide these services are highly interdependent through a number of physical, economic and organizational links. In this context, a holistic perspective on risk is essential to avoid suboptimal interventions and risk-related blind spots. Here, fragme

Objective: This paper analyses intergenerational relationships in Sweden during the corona pandemic, with a special focus on practices of care. The research question is: How is care between generations – between grandparents, adult children and grandchildren – done during pandemic conditions? Background: In Sweden, where an extensive welfare state provides affordable child- and eldercare, the coro

BACKGROUND AND AIMS: The disease course of acute pancreatitis (AP) ranges from mild and self-limiting to severe inflammation, associated with significant morbidity and mortality. At present, there are no universally accepted and reliable predictors for severity. Microproteinuria has been associated with the presence of systemic inflammatory response syndrome as well as trauma, although its associa

Introduction Healthcare databases are useful sources to investigate the epidemiology of chronic obstructive pulmonary disease (COPD), to assess longitudinal outcomes in patients with COPD, and to develop disease management strategies. However, in order to constitute a reliable source for research, healthcare databases need to be validated. The aim of this protocol is to perform the first systemati

This article describes a logistics-based framework for organizational change of service organizations. This framework is based on the key concepts of modern logistics: systems thinking for a holistic approach to business; process orientation for structure of the organization; and process management for continuous change and improvement. The development of logistics as a research and practitioner d