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Din sökning på "research studies portal" gav 71392 sökträffar

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Objective: To better understand the seemingly contradictory plasma beta-amyloid (A beta) results in Alzheimer's disease (AD) patients by using a newly developed plasma A beta assay, the INNO-BIA plasma A beta forms, in a multicenter study. Methods: A combined retrospective analysis of plasma A beta isoforms on mild cognitive impairment (MCI) from three large cross-sectional studies involving 643 s

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Cooling vests incorporated with phase change materials (PCMs) add extra insulation and restrict sweat evaporation. It is still unclear how much cooling benefit they can provide. The aim of this study was to investigate the torso cooling of the PCM vests in two hot environments: hot humid (HH, 34C, 75% relative humidity (RH)) and hot dry (HD, 34C, 37% RH). A pre-wetted torso fabric skin was used to

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OBJECTIVE: This study of myocardial infarction (MI) amongst urban women has sought to assess whether there are differences in fatal outcome, in-hospital respectively out-of-hospital, between residential areas defined in terms of socio-economic circumstances. DESIGN: Register-based surveillance study 1986-95. SETTING: Seventeen residential areas in the city of Malmo, Sweden. SUBJECTS: Women 20-74 y

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Several studies have found that the homocysteine plasma level is associated with cardiovascular disease. The authors previously described a relationship between concentrations of fibrinogen and other inflammation-sensitive plasma proteins, namely, alpha1-antitrypsin, ceruloplasmin, haptoglobin, and orosomucoid (alpha1-acid glucoprotein) and the incidence of myocardial infarction (MI). Whether leve

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For the last many decades industry and insurance companies have been interested in protecting high racked goods from rapid fire growth. This has mainly been done by installing sprinklers of various types and designs in order to either extinguish the fire or control it. The efficiency of such protection measures is, however, very much dependant on the geometry of the stacks, their height, floor are

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Fibroblast growth factor 8 (FGF-8) is expressed in a large proportion of breast cancers, whereas its level in normal mammary gland epithelium is low. Previous studies have shown that FGF-8b stimulates breast cancer cell growth in vitro and in vivo. To explore the mechanisms by which FGF-8b promotes growth, we studied its effects on cell cycle regulatory proteins and signalling pathways in mouse S1

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Objective: The objective of this study was to investigate quality of life (QoL) in patients with Graves' disease treated with radioiodine or antithyroid drugs. Design and methods: The design of the study consists of an open, prospective, randomized multicenter trial between radioiodine and medical treatment. A total of 308 patients were included in the study group: 145 patients in the medical grou

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The purposes of the study are to compare point-of-care (POC) hemostatic devices in critically ill patients with routine laboratory tests and intensive care unit (ICU) outcome scoring assessments and to describe the time course of these variables in relation to mortality rate.

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Popular Abstract in Swedish Glukos (druvsocker) är den primära energikällan för människan. Därför är det viktigt att effektivt kunna lagra extra socker från blodcirkulationen efter måltider, och att snabbt kunna använda det upplagrade sockret mellan måltiderna. Glykogen är upplagringsformen av socker i cellerna och en glykogenmolekyl kan bestå av tiotusentals glukosmolekyler. Glykogensyntesen reglEffective insulin-stimulated storage of excess glucose after a meal, and its rapid mobilisation in the fasting state provide basis of glucose homeostasis. Glycogen is the macromolecular storage form of glucose and glycogen synthase (GS) is the rate-limiting enzyme in glycogen synthesis. Skeletal muscle and liver are the major depots of glycogen. The present studies were undertaken to isolate and c

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This book presents actual perspectives on Church History from different standpoints. It is the result of an academic conference on Ecclesiastical History in Stockholm, Feb. 27-28, 2008. The volume starts with a chronological section in which different research developments in Ancient, Medieval, Reformation and Modern Church History are demonstrated by authors from the Scandinavian countries and th

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In this grounded theory study, the authors interviewed caregivers andpatients in end-of-life cancer care and found Balancing to be a fundamentalprocess explaining the problem-solving strategies of most participants and offering a comprehensive perspective on both health care in general and end-of-life cancer care in particular. Balancing stages wereWeighing— sensing needs and wishes signaled by pa

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Popular Abstract in Swedish Autoimmuna sjukdomar såsom reumatoid artrit (RA) och multipel skleros (MS) uppkommer av en felaktig immunrespons mot kroppens egen vävnad. Orsaken är okänd trots enormt mycket forskning om ämnet. Ett sätt att öka kunskapen vore att identifiera de gener som bidrar till sjukdomarna. För sådana relativt vanliga, komplexa sjukdomar finns det inte en gen som ?styr? sjukdomarAutoimmune diseases are dependent on both genetic and environmental factors in complex interplay. They arise from a faulty immune response against self-antigens, and causes great suffering in affected individuals. Despite large efforts and hundreds of thousands of research articles published, the disease etiologies remain largely unknown. Knowledge of which genes are involved and how they interact

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Background: Thyroid hormones are important for normal fetal development. Maternal hypothyroidism during early pregnancy is associated with impaired neuropsychological development of children and other adverse outcomes. The primary aim of this prospective study was to determine whether thyroxine-treated pregnant women with hypothyroidism are adequately thyroxine substituted in early pregnancy. A se

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Autologous dermal fibroblasts may be useful in the treatment of diabetic skin wounds. We hypothesized that cultured fibroblasts or cultured keratinocytes would not only survive in a hyperglycemic wound environment but also enhance the rate of re-epithelialization. We previously developed a new porcine model of delayed cutaneous wound healing in the diabetic pig. Full thickness wounds were created

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Popular Abstract in Swedish Spårbarhet av livsmedel för att garantera ursprung, kvalitet och säkerhet i samband med produktion och transport har blivit alltmer uppmärksammat i samhället. Kraven på att livsmedel skall vara kvalitetsmässigt säkerställda samt miljömässigt hållbara har vuxit sig starkare från konsumenter såväl som från myndigheter. En bidragande orsak är den ökade fokuseringen kring bFood traceability is gaining increased attention in food companies and governmental authorities. This is because of the increase in legal and consumer requirements on ensuring food safety, quality and preservation of living resources. These requirements especially apply to the management of food traceability in regulated fresh food supply chains. Several studies have shown that management of food

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In order to study the effect of different intensities of anti-vitamin K treatment on coagulation parameters, 23 patients with venous thromboembolism were given, after the initial treatment period, warfarin at doses giving an International Normalised Ratio of 1.3-2.0 for 4 weeks, and of 1.1-1.3 for another 4 weeks. Blood samples were taken at the end of each of these periods and 4 weeks after the e

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BACKGROUND/AIM: Vasopressin and oxytocin are closely related peptides, and both exert effects on the gastrointestinal function. In the present study, we wanted to map the expression of vasopressin receptor mRNAs (V1a, V1b/V3, and V2) in nontumorous tissue biopsy specimens of human gastrointestinal tract and surrounding tissues. METHODS: Total and polyA+ RNAs were isolated from human tissue biopsy