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Neuropeptide Y (NPY) has been shown to be involved in the control of several neuroendocrine functions. Moreover, in animal models, NPY produces behavioral effects that are similar to those induced by anxiolytics. We studied NPY-like immunoreactivity (NPY-LI) in cerebrospinal fluid (CSF) in two primary degenerative dementias, Alzheimer disease (AD, n = 34) and frontotemporal dementia (FTD, n = 22)
Informal investors have been highlighted as important stakeholders for potential high-growth ventures. Extant empirical research provides evidence that they contribute not only with money but also bring added value in terms of providing their skills and experience to support the continued development and growth of the ventures in which they have invested. However, despite the reported benefits of
BACKGROUND AND PURPOSE: The experience of having a child monitored for vital signs in relation to surgery for congenital heart disease can be highly stressful for parents. The opportunity to be involved in their child's care is central to parents' well-being and to their overall experience of the care provided. The purpose of this study was to explore how parents of children with congenital heart
BACKGROUND: Atrial fibrillation (AF) burden is associated with adverse outcomes; in some patients, very low AF burden may not be actionable.OBJECTIVE: This study aimed to model AF burden as a function of monitoring time without AF.METHODS: We included 11,639 US patients (median age 62 years [interquartile range 46‒73], 40.6% male) without permanent/persistent AF, monitored for ≥14 days in 2021 wit
Experience of abuse as a life event is common among men in a psychiatric care context. Systematically charting life events and abuse plays a central role within psychiatric and mental health nursing and could improve the understanding of the patient’s life situation. The aim of the study was to explore the life course of male psychiatric patients who had experienced domestic abuse as victims and a
Teledermoscopy (TDS) offers an efficient alternative to face-to-face assessment of suspicious skin lesions. Although diagnostic accuracy in TDS is relatively high, further improvement is desirable to reduce the risk of overlooked skin cancers and unnecessary interventions of benign lesions. Image enhancement (IE), i.e. digital modification of different parameters of an image, may potentially impro
The influence of module configuration on the ultrafiltration of highly concentrated fluids in tubular membrane plants was investigated. Previous work has shown that frictional pressure drop in the feed flow channel can have a significant influence on the performance when treating viscous fluids. In the present study, three module alternatives were compared: polymeric membranes connected either in
Several coastal areas in the south of Sweden are subjected to flooding and erosion. Such events depend on the magnitude and frequency of water levels and wave heights as well as their joint occurrence. Long time series of climate data from the south coast of Sweden were employed to investigate the statistical properties of extreme events in terms of the waves and water level changes. Through the c
Purpose - The purpose of this paper is to explore the "black box" of top management team (TMT) processes such as communication and power distribution, examining the example of ethnically diverse TMTs in Latvia. Design/methodology/approach - The study relies on case studies of two multinational companies operating in Latvia. Findings - The findings suggest that ethnic diversity in TMTs leads to mor
Recent studies indicate a severely reduced coronary flow reserve (CFR) in neonates with congenital heart disease. The significance of these studies remains debatable, as the ability of the anatomically normal neonatal heart to increase coronary flow is currently unknown. This study was designed to establish normal values for CFR in newborns after administration of adenosine [pharmacologic CFR (pCF
Neuron glial 2 (NG2) cells become strongly activated in injured brain areas. The activation is characterized by increased proliferation as well as increased expression and shedding of the proteoglycan NG2 expressed on their cell surface. It is currently not known how these cells respond to low-grade neuroinflammation provoked by systemic inflammation. To investigate this, we analyzed NG2 cell prol
During past decades, the number of dentists has continuously increased in Iran. Beside the quantity, the distribution of dentists affects the oral health status of population. The current study aimed to assess the pure and social disparities in distribution of dentists across the provinces in Iran in 2009. Data on provinces' characteristics, including population and social situation, were obtained
Bone marrow stromal cells (BMSC) have gained increased attention because of their multipotency and adult stem cell character. They have been shown to differentiate into other cell types of the mesenchymal lineage and also into non-mesenchymal cells. The exact identity of the original cells, which are isolated from bone marrow by their selective adherence to plastic, remains unknown to date. We hav
Inflammation caused by the accumulation of oxidized low-density lipoprotein (oxLDL) in the arterial wall is a key factor in the development of atherosclerosis. Accumulating evidence suggests that adaptive immune responses to oxLDL are of major importance in regulating the inflammatory response, and that humoral immunity largely has a protective effect in this process. This concept is supported by
Yeasts belonging to the lineage that underwent whole-genome duplication (WGD) possess a good fermentative potential and can proliferate in the absence of oxygen. In this study, we analyzed the pre-WGD yeast Kluyveromyces lactis and its ability to grow under oxygen-limited conditions. Under these conditions, K. lactis starts to increase the glucose metabolism and accumulates ethanol and glycerol. H
This paper deals with a continuous review inventory system with Poisson demand, in which lateral transshipments are allowed. In case of a shortage at a location, another location acts as a supplier, if it is possible. A common assumption in earlier papers is that transshipments are allowed between all locations. This network configuration may, however, not be the best choice for many reasons. one
We argue that leadership promotion in China’s political elite relies on homophily for signals of trustworthiness and future cooperative behavior more than on economic performance. We first point to the limitation of the economic performance argument from within the framework of China’s specific M-form state structure, and then we proffer a sociological explanation for why higher-level elites in Ch
Postoperative peritoneal carcinomatosis together with adhesion formation are considered as two major clinical complications after resection of malignant abdominal tumors, jeopardizing the beneficial effect of the curative surgery. Biobarrier is a novel anti-adhesive barrier fulfilling the criteria for a good adhesion preventive agent, possessing biochemical properties that may enable it to functio
