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ATP-dependent priming of the secretory granules precedes Ca(2+)-regulated neuroendocrine secretion, but the exact nature of this reaction is not fully established in all secretory cell types. We have further investigated this reaction in the insulin-secreting pancreatic B-cell and demonstrate that granular acidification driven by a V-type H(+)-ATPase in the granular membrane is a decisive step in
The study of entrepreneurship has become one of the most popular fields of research in the area of management over the last few decades. New and small businesses are seen collectively by politicians and decision-makers as the main contributors to the development of the economy and wealth creation in society. Sten K. Johnson Centre for Entrepreneurship conducts internationally renowned research wit
What role does the state play in economic development? This thesis seeks to investigate the relationship between a strong state and economic development. To define the concept of a strong state I focus on the relationship between the scope of state functions and the efficiency of which these functions are implemented. The concept of a strong state is in this thesis defined as the efficiency of the
The rhizosphere priming effect (RPE) is increasingly being considered to be an important regulator of soil organic matter (SOM) decomposition and nutrient turnover, with potential importance for the global CO2 budget. As a result, studies on the RPE have rapidly increased in number over the last few years. Most of these experiments have been performed using unplanted soil as the control, which cou
Microsoft Word - Bjorkliden 2013 Rapport.docx ! 1! BJÖRKLIDEN+2013:+Det+femte+året+ I!Lunds!universitets! (LU)!nuvarande! strategiska!plan!är!ett! av!de!övergripande!målen! gränsöverskridande!samverkan.!Genom!LMK!stiftelsens!försorg!har!elva!yngre!forskare! vid!LU!under!en! fyradagarsvistelse! i!Björkliden! fått!möjlighet!att!diskutera! frågor!som! behovet!av,!och!hur!man!motiverar!och!underlättar
https://www.pi.lu.se/sites/pi.lu.se/files/bjorkliden_2013_rapport.pdf - 2026-07-11
beta-1,4-Gatactosyltransferase 7 (beta 4GalT7) is an essential enzyme in the biosynthesis of glycosaminoglycan (GAG) chains of proteoglycans (PGs). Mammalian cells produce PGs, which are involved in biological processes such as cell growth and differentiation. The PGs consist of a core protein, with one or several GAG chains attached. Both the structure of the PGs and the GAG chains, and the expre
The side-feeding patterns and the spectra of unresolved γ-lines are calculated for Gd, Dy and Er nuclei with neutron numbers from 82 to 86. Energies and configurations for states from the yrast line and approximately 2 MeV higher in energy are calculated as many-quasiparticle configurations in a deformed oblate potential. The γ-cascade is simulated by a Monte Carlo calculation. With a common avera
SOL ENGA03 VT 2017 Kursutvärderingsrapport SOL ENGA03 V17 Respondents: 49 Answer Count: 22 Answer Frequency: 44.90 % Kön Kön Number of Responses Kvinna 14 (63.6%) Man 7 (31.8%) Annat 0 (0.0%) Vill inte svara 1 (4.5%) Total 22 (100.0%) Mean Standard Deviation Kön 1.3 0.5 Ålder Ålder Number of Responses Under 30 21 (95.5%) Över 30 1 (4.5%) Total 22 (100.0%) Mean Standard Deviation Ålder 1.0 0.2 Hur
https://www.sol.lu.se/media/utbildning/dokument/kurser/ENGA03/20171/SOL_ENGA03_VT_2017_Kursutv_rderingsrapport.pdf - 2026-07-10
In some patients, graft-induced dyskinesia develops following intrastriatal transplantation of embryonic neural tissue for the treatment of Parkinson's disease. The mechanisms underlying these involuntary movements need to be clarified before this approach to clinical cell therapy can be developed further. We previously found that rats with 6-OHDA lesions, primed with L-DOPA treatment and that hav
SHus P, Van19061013130 LUNDS UNIVERSITET PROTOKOLL 2019:3 2019-05-29 Dnr STYR 2019/989 Ledningsgruppen for beteendevetenskapligt kandidatprogram Ledningsgruppens protokoll Narvarande Ledamoter Ovriga Anmalt forhinder Anna Hjalmers Mattsson, ordforande Magnus Karlsson, lararrepresentant, soc Jean Christophe Rohner, lararrepresentant, psy Anna Sirhed, studentrepresentant Ingela Steij Scilbrand, lara
https://www.psy.lu.se/sites/psy.lu.se/files/protokoll_3_2019-05-29.pdf - 2026-07-11
Recent studies implicated the existence of adult lymphoid-primed multipotent progenitors (LMPPs) with little or no megakaryocyte-erythroid potential, questioning common myeloid and lymphoid progenitors as obligate intermediates in hematopoietic stem cell (HSC) lineage commitment. However, the existence of LMPPs remains contentious. Herein, global and single-cell analyses revealed a hierarchical or
Popular Abstract in Swedish Övervikt är ett av vår tids största hälsoproblem, kanske till och med det största. Det finns de som menar att redan idag utgör övervikt globalt sett en viktigare orsak till sjukdom än undernäring och infektionssjukdomar. Framtidsscenariot beskrivs som alarmerande. Folk kommer att i en tidigare aldrig skådad omfattning insjukna i överviktens följdsjukdomar. Medierna harThe prevalence of overweight and obesity is rising each year not only on a national but also on a global level. The future scenario is troublesome. The media are among the most important social institutions in influencing people’s knowledge, perceptions and actions. The media provide citizens with health messages and contribute thereby to their health development. This dissertation deals with two
Development of B-lymphoid cells in the bone marrow is a process under strict control of a hierarchy of transcription factors. To understand the development of a B-lymphoid-restricted functional network of transcription factors, we have investigated the cell autonomous role of the transcription factor EBF1 in early B cell development. This revealed that even though transplanted EBF1-deficient fetal
