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The impact of sperm DNA damage in assisted conception and beyond: recent advances in diagnosis and treatment

Sperm DNA damage is a useful biomarker for male infertility diagnosis and prediction of assisted reproduction outcomes. It is associated with reduced fertilization rates, embryo quality and pregnancy rates, and higher rates of spontaneous miscarriage and childhood diseases. This review provides a synopsis of the most recent studies from each of the authors, all of whom have major track records in

Arterial stiffness and influences of the metabolic syndrome: A cross-countries study.

Specific clusters of metabolic syndrome (MetS) components impact differentially on arterial stiffness, indexed as pulse wave velocity (PWV). Of note, in several population-based studies participating in the MARE (Metabolic syndrome and Arteries REsearch) Consortium the occurrence of specific clusters of MetS differed markedly across Europe and the US. The aim of the present study was to investigat

Prognostic and treatment predictive factors for radio- and chemotherapy resistance in breast cancer patients- a step towards personlized medicine

Breast cancer is the most common cancer form among women in the Western world. Although treatment has improved during the last decades, there is still a significant proportion of the patients who are not cured. To further improve clinical outcome we need new treatment strategies, new prognostic markers, and new treatment predictive factors for personalized medicine.In this dissertation I have focu

Le respect de la tradition : Om den franska flöjtkonsten: dess lärande, hantverk och estetik i ett hermeneutiskt perspektiv

ABSTRACT The present study describes topics related to music education, and the education of flautists, primarily on a professional level, covering a period from early 18th Century up to the early 21st Century within the French flute tradition. Further related areas of importance are concepts such as intuition, imitation, mimeses and maieutics and their relation to a flautist’s learning and teachi

Recension av Swedish Students at the University of Leipzig in the Middle Ages

The book contains editions and studies of texts produced by Swedish academics active at the University of Leipzig in the fifteenth century. Academic texts from the Middle Ages are difficult to digest; the editions, translations and studies presented in this book and its companion volumes make them as accessible to the modern reader as one can possibly ask.

Declines amongst breeding Eider Somateria mollissima numbers in the Baltic/Wadden Sea flyway

We report on the status of the Baltic/Wadden Sea flyway Eider population based on trends in breeding and wintering numbers throughout the region, supplemented by changes in the sex ratio and proportion of young Eiders as monitored in the Danish hunting bag. At the flyway scale, total numbers of breeding pairs decreased by 48% during 2000-2009, after relatively stable breeding numbers in 1991-2000.

Development and regulation of alveolar fluid clearance in the guinea pig

Popular Abstract in Swedish För att lungorna ska utvecklas normalt hos ett däggdjursfoster, måste lungorna vara vätskefyllda. Det har länge varit kännt att denna vätska produceras av lungorna själva, genom s k klorid-sekretion. Vid födelsen måste det nyfödda fostret börja andas och därför är det ytterst viktigt att lungorna snabbt töms på vätskan som fanns där under fosterutvecklingen. Detta sker Alveolar fluid clearance is driven by active absorption of Na+ across the alveolar epithelium. Development and hormonal regulation of alveolar fluid clearance over 1 hour was studied by instillation of a protein-containing, isosmolar fluid into lungs of fetal, newborn, and adult guinea pigs. After 1 hour, a sample of remaining alveolar fluid was collected and the change in protein concentration wa

Hydrogen production by thermophilic fermentation

Of the many ways hydrogen can be produced, this chapter focuses on biological hydrogen production 12 by thermophilic bacteria and archaea in dark fermentations. The thermophiles are held as promising candidates 13 for a cost-effective fermentation process, because of their relatively high yields and broad substrate palette. Yet 14 many challenges remain to be faced, including improving productivit

Reducing Emissions from Deforestation and Degradation in Peru: a challenge to social inclusion and multi-level governance

REDD is one of the latest additions to a series of incentive-based mechanisms for reducing carbon emissions. Although international negotiations have not eliminated uncertainties regarding its social, economic and political implications, many developing and emerging countries have begun to engage in REDD. Peru, the country with the world’s fourth largest tropical forest area has good reason to par

Beta-glucose 1-phosphate interconverting enzymes in Lactococcus lactis: physiological role and regulation in maltose, trehalose and glucose metabolism

Lactic acid bacteria (LAB), including Lactococcus lactis, are abundant in nature. These bacteria convert carbohydrates into mainly lactate by a rather uncomplicated metabolism. An improved understanding of the physiological and genetical mechanisms involved in carbohydrate metabolism and its regulation will improve the industrial use of LAB. The aim of this study was to investigate the maltose an

När något blir annorlunda : skötsamhet och funktionsförmåga i berättelser om poliosjukdom

When something is different: respectability and bodily ability in stories about polio In this thesis I study the relationship between people’s stories about polio and norms concerning respectability and ability. The purpose is to examine sense-making processes surrounding polio disease. This is done by studying how the ”normality” and ”deviation” is produced and negotiated in individual stories a

A combined method for evaluating criteria when selecting ERP systems

There are many benefits offered by integrated enterprise computer systems. There are a growing number of options available to obtain such management information system support. A major problem when selecting Enterprise Information Systems, in special ERP systems, is how to deal with the great diversity of options as well as the number of criteria used to evaluate each alternative. There is an impl

Metallacyclic Phosphine Complexes and Intramolecular Csp3-H Bond Activation -Synthesis, Characterisation and Catalytic Application

Popular Abstract in Swedish Katalytisk omvandling av enkla kolväten till mer användbara substanser m.h.a. homogena/lösliga komplex av övergångsmetaller är ett mycket viktigt ämnesområde inom metallorganisk kemi. För att förstå hur processen går till har ett stort antal modellföreningar syntetiserats genom åren där man har studerat hur kol-väte eller kol-kol bindningar kan brytas. Man bör notera atThe work presented in this thesis deals with metallacyclic late transition metal complexes, obtained by intramolecular Csp3-H activation, and the application of such compounds in catalysis. The new hemilabile P,O phosphines N-methyl-N-propionyl-2-(diphenylphosphino)benzylamine (DPPAM), o-(diphenylphosphino)benzoic acid ethyl ester (DPPES), o-(diphenylphosphino)benzoic acid methyl ether (DPPET) and

Structural Change and the Fall of Income Inequality in Latin America : Agricultural Development, Inter-sectoral Duality, and the Kuznets Curve

In this study we approach the recent decline in income inequality in Latin America from the perspective of structural change with a focus on the relative performance of the agricultural sector. Our focus is on the underlying forces implied by Kuznets (1965). We zoom in on the relative performance of agriculture in the development process and the rural-urban duality and pay particular attention to

Role of stray light in the formation of high-resolution resonant photoelectron spectra: an experimental and theoretical study of N-2

We show that the undular stray light, diffusely scattered by the optical system of a synchrotron beamline, can play an important role in the formation of high-resolution resonant photoelectron (RPE) spectra. The influence of the stray light is mediated through the Stokes doubling effect, with the Lorentzian tail of the spectral function being replaced by a more complicated form. This effect is sho

Band-terminating states in Ag-101

Excited states of the neutron deficient Ag-101 nucleus have been investigated via the Cr-50(Ni-58, 3rho1alpha) heavy-ion induced reaction at 261 meV by use of in-beam spectroscopic methods. On the basis of the measured gammagamma-cincidence relations and angular distribution ratios high-spin bands have been extended up to I-pi = 35/2(+), 45/2((-)) and (49/2(-)). The negative parity states at the h

Three-body correlations in Borromean halo nuclei

Three-body correlations in the dissociation of two-neutron halo nuclei are explored using a technique based on intensity interferometry and Dalitz plots. This approach provides for the combined treatment of both the n-n and core-n interactions in the exit channel. As an example, the breakup of 14Be into 12Be+n+n by Pb and C targets has been analyzed and the halo n-n separation extracted. Evidence