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Background & aims: Short telomeres have been observed in chronic disease patients. Identifying environmental and lifestyle factors that could reduce telomere attrition is crucial for disease prevention. The aim of this work was to determine whether weight-loss induced by an energy-reduced Mediterranean diet (erMedDiet) and physical activity (PA) could modify telomere length (TL). Methods: In 3

The diagnosis of peripheral arterial disease (PAD) is not always evident as symptoms and signs may show great variation. As all grades of PAD are linked to both an increased risk for cardiovascular complications and adverse limb events, awareness of the condition and knowledge about diagnostic measures, prevention and treatment is crucial. This article presents in a condensed form information on P

BACKGROUND: Stereotypes may prevail, but little is known about the influence that the sex of an orthopaedic surgeon may have on outcomes. In a recently published study, there were no differences in the rate of adverse events following total hip arthroplasties (THAs) performed by female or male orthopaedic surgeons. The objective of the present study was to investigate whether there was any differe

UNLABELLED: Intraoperative radiographic guidance has traditionally been utilized in orthopedic surgery through 2-D navigation with the C-arm and recently with 3-D navigation with the O-arm. The aim of this study was to describe the outcome of surgical treatment of spinal osteoblastoma and osteoid osteoma with the utilization of the O-arm and conventional C-arm guidance. This is a retrospective coh

We have studied the nature of the S 2p → 4eg shape resonance in the SF6 molecule by performing two different experiments. Soft X-ray emission spectra measured at the 4eg shape resonance reveal features that do not originate from the S 2p-1 states. One of the features can be assigned to the 6a1g → S 2p transition. The 6a1g orbital, which is empty in the molecular ground state, can be populated eith

Background: This study assessed the cost-effectiveness of proton beam therapy (PBT) compared to conventional radiotherapy (CRT) for treating patients with brain tumors in Sweden. Methods: Data from a longitudinal non-randomized study performed between 2015 and 2020 was used, and included adult patients with brain tumors, followed during treatment and through a one-year follow-up. Clinical and demo

High latitude peatlands play a significant role in global soil carbon budgets, attributed to the slow decomposition rate of Sphagnum mosses that facilitates carbon sequestration through the build-up of peat. As climate change is predicted to increase soil temperatures and decomposition rates of organic matter, studying environmental and intraspecific mechanisms that controls decay resistance of Sp

The effects of atmospheric aerosols are key uncertainties in climate models. One reason is the complex aerosol composition which includes a relatively large fraction of organics. Another reason is the small size of aerosols, which makes surface effects and processes important. These two factors make surface-active organics relevant for atmospheric aerosols, as they can affect crucial processes, su

We describe an experimental setup for non-linear interaction and propagation of ultrashort and intense x-ray free-electron laser (XFEL) pulses in a dense gas. It allows one to provide high, but adjustable, target-gas pressures of up to 6 bar within a vacuum environment of 3∙10− 3 mbar or better. The setup enables investigation of intense x-ray propagation in an optically thick medium with minimal

Urban climate resilience planning often overlooks the subsurface, despite its potential to mitigate flooding, heat stress, and drought. To demonstrate these potentials, we developed thematic Geosystem Service (GS) maps for Malmö, Sweden, to support the integration of the subsurface into climate adaptation strategies. This study identifies GS relevant to the local context, proposes indicators for m

Understanding the genetic regulation of blood CD34+ cell levels could lead to better methods for stem cell mobilization and transplantation. Recently, in a genome-wide association study (GWAS), we identified 11 genetic associations with blood CD34+ cell levels. One of the most significant maps to an intergenic region between the ENO1 and RERE genes at chromosome 1p36.23. However, the underlying me

This guidebook offers practice‑oriented guidance for initiating, developing, and sustaining collaborative housing projects across Europe. Building on the EU‑funded CO‑HOPE (Collaborative Housing in a Pandemic Era) research project and its Urban Living Lab, it synthesizes insights from the planning processes of studied collaborative housing initiatives. Grounded in participatory workshops with resi

In epidemiological studies, obsessive-compulsive disorder (OCD) is robustly associated with increased risk of cardiometabolic disorders, including cardiovascular diseases, type 2 diabetes, and obesity. However, the mechanisms behind these associations are unclear. We conducted genetic correlation analyses to explore shared genetic etiology and bi-directional summary-level Mendelian randomization (

This thesis investigates core excited electronic states of molecules in gas phase. In particular, the resonanttransitions of ionised molecules, the site-selectivity surrounding Auger-Meitner decay, and the nuclear dynamicsthat may follow core excitation and ionisation.Background: Fundamental understanding of molecules and ions lay the groundwork for all future applicativescience and production. Fo

Even if much is known regarding the effects of internet-delivered cognitive behaviour therapy (ICBT) for depression there are several topics that have not been studied. In this factorial design trial with 197 participants we investigated if clients in ICBT could select treatment modules themselves based on a selection of 15 tailored treatment modules developed for use in ICBT for depression. We co

Objectives: To evaluate the impact of the 2018 switch from PCV13 to PCV10 in Sweden’s childhood immunisation programme on the serotype distribution of Streptococcus pneumoniae.MethodsRespiratory tract (RT) S. pneumoniae isolates (n=1615; 2020–2023) were serotyped, tested for antimicrobial susceptibility and compared with invasive pneumococcal disease (IPD) isolates (n=397) and PCV13-era data (2016

In this paper, we introduce a generalized dynamical unbalanced optimal transport framework by incorporating limited control input and mass dissipation, addressing limitations in conventional optimal transport for control applications. We derive a convex dual of the problem using dual optimal control techniques developed before and during the 1990s, transforming the non-convex optimization into a m

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Lineage tracing of stem cell–derived dopamine grafts in a Parkinson’s model reveals shared origin of all graft-derived cells Storm et al., Sci. Adv. 10, eadn3057 (2024) 18 October 2024 S c i e n c e A d v A n c e S | R e S e A R c h A R t i c l e 1 of 14 N E U R O S C I E N C E Lineage tracing of stem cell–derived dopamine grafts in a Parkinson’s model reveals shared origin of all graft- derived c

https://www.regenerative-neurobiology.lu.se/sites/regenerative-neurobiology.lu.se/files/2024-11/publication%20in%20Science%20Advances.pdf - 2026-06-06