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Wuthering Weights—Localisation Trajectories of Machine Learning Models for Local Ends

This chapter analyses trajectories of contextual reconstruction of machine learning models with calibrated weights, sometimes known as pre-trained or foundation models, as they are made operational in specific settings. Through ethnographic vignettes on car detection, bird tracking, and medical technology, it underscores the importance of cooperation and negotiation among actors facing contingenci

C-Glycosylation in platinum-based agents : a viable strategy to improve cytotoxicity and selectivity

Novel coordinatively saturated platinum(ii) compounds bearing C-linked carbohydrates were synthesized and characterized. The complexes exhibit bipyramidal trigonal geometry with a bidentate nitrogen ligand and ethylene in the equatorial plane. The axial positions are occupied by a halide ligand X and a d-galactose or d-glucose derivative, linked either via C1 or C6. The compounds were designed for

SRPNet : stroke risk prediction based on two-level feature selection and deep fusion network

Background: Stroke is one of the major chronic non-communicable diseases (NCDs) with high morbidity, disability and mortality. The key to preventing stroke lies in controlling risk factors. However, screening risk factors and quantifying stroke risk levels remain challenging. Methods: A novel prediction model for stroke risk based on two-level feature selection and deep fusion network (SRPNet) is

Investigating the differences in calculating global mean surface CO2 abundance: the impact of analysis methodologies and site selection

The World Meteorological Organization (WMO) Global Atmosphere Watch (GAW) coordinates high-quality atmospheric greenhouse gas observations globally and provides these observations through the WMO World Data Centre for Greenhouse Gases (WDCGG) supported by Japan Meteorological Agency. The WDCGG and the National Oceanic and Atmospheric Administration (NOAA) analyse these measurements using different

Resolving uncertainty in the response of Australia's terrestrial carbon cycle to projected climate change

Semi-arid ecosystems, common across the Australian continent, strongly influence the inter-annual variability and trend in the global terrestrial net carbon sink. Here we explore the future Australian terrestrial carbon cycle using the CMIP6 ensemble, and the dynamic global vegetation model LPJ-GUESS. Uncertainty in Australia's carbon storage in vegetation ranged between 6 and 49 PgC at the end of

Seismic Measurements Using Distributed Acoustic Sensing (DAS) for Underwater Soft Sediment Characterization : Insights from Laboratory- and Field-Scale Measurements

Scholte wave surveys were conducted at both the laboratory and field scales to evaluate the reliability of distributed acoustic sensing (DAS) with a fiber-optic cable resting on top of unconsolidated sedimentary deposits to determine the distribution of S-wave velocity underneath. Laboratory measurements performed in a controlled environment at the Deltares Laboratory facility demonstrated that DA

Multistakeholder governance through epistemic authority : exploring the role of the Climate and Clean Air Coalition in the global climate regime

The global climate change governance landscape is rapidly evolving. Non-state actors and institutions increasingly challenge the formal authority of the United Nations Framework Convention on Climate Change (UNFCCC), operating in parallel with its intergovernmental processes. In particular, multi-stakeholder partnerships (MSPs) carry out several policy functions, becoming established actors within

What roles do governments play vis-à-vis niche actors? A typology illustrated with transition dynamics in the Dutch agri-food system

Regime change is considered essential for sustainability transitions. An important source of regime change is pressure from alternative innovations developed in niches and the actors involved. Governments often play an important role in such niche-regime interactions and affect whether, and how, this results in regime change. However, an overview of the various roles governments can play with resp

On the Stability of Dynamical Multi-Commodity Flow Networks

We study a class of dynamical multi-commodity flows in transportation networks. These are modeled as dynamical systems describing the evolution of the densities of a number of different commodities across the cells of a transportation network. Each cell is characterized by commodity-specific increasing demand functions returning the maximum outflow of each commodity from the cell as a function of

Certifying Combinatorial Optimization : A Unified Approach Using Pseudo-Boolean Reasoning

Combinatorial optimization is a powerful way to solve complex problems, like planning, scheduling, or hardware verification, by expressing the problem in a mathematical form using discrete variables that can be solved by general solvers. Due to major advances in algorithms for solving combinatorial optimization problems, these solvers can tackle real-world challenges efficiently. However, as solve

Referral Indications for Malignant Hyperthermia Susceptibility Diagnostics in Patients without Adverse Anesthetic Events in the Era of Next-generation Sequencing

Background: The introduction of next-generation sequencing into the diagnosis of neuromuscular disorders has resulted in an increased number of newly identified RYR1 variants. The hypothesis was that there is an increased referral of patients to malignant hyperthermia units without a personal/family history of adverse anesthetic events suspected to be malignant hyperthermia. This retrospective mul

The comfort of alignment: Mining, green steel, and killjoy desires in Sweden/Sápmi

Denna avhandling fokuserar på svensk extraktivism i Sápmi/Norrbotten genom att studera den planerade järnmalmsgruvan i Gállok/Kallak och den gröna omställningen inom stålproduktionen. Huvudsyftet är att förstå tilltron till resursutvinning som ett sätt att nå en lycklig, grön, och god framtid. Med utgångspunkt i psykoanalys läser jag resursutvinning som ett begärsobjekt som människor söker sig tilThis dissertation deals with Swedish extractivism in Sápmi through the examples of a planned iron ore mine in Gállok/Kallak and the hydrogen-based steel transition. The main aim is to understand the trust that is placed in extraction as a means to arrive at a happy, prosperous, green future. Drawing on Lacanian psychoanalysis and Sara Ahmed’s notion of the promise of happiness, I suggest that extr

Minimal Optimism : Reading P. F. Strawson on Responsibility

Peter Strawson’s ‘Freedom and Resentment’ (1962) has reoriented the way moral philosophers think about responsibility. There is a general sense that Strawson’s approach holds the promise that we may move beyond the traditional discussion of free will in recognition of the fact that whether determinism is true is irrelevant for whether we are responsible beings. This is Strawson’s Promise. This the

Stormy records from peat bogs in south-west Sweden : implications for regional climatic variability and vegetation changes during the past 6500 years

This thesis aims to reconstruct and explain variations in storm activity, humidity, vegetation composition and land cover in south-west Sweden during the past 6500 years. Two ombrotrophic bogs, Store Mosse and Undarsmosse, situated on the coastal plain of Halland, were selected for this purpose. The coastal plain of Halland is positioned in the cyclone path and is therefore particularly sensitive

Amplitude integrated EEG 3 and 6 hours after birth in full term neonates with hypoxic-ischaemic encephalopathy

AIM: To assess the prognostic value of amplitude integrated EEG (aEEG) 3 and 6 hours after birth. METHODS: Seventy three term, asphyxiated infants were studied (from two different centres), using the Cerebral Function Monitor (CFM Lectromed). The different aEEG tracings were compared using pattern recognition (flat tracing mainly isoelectric (FT); continuous extremely low voltage (CLV); burst-supp

The white library of the red rose : Petr Wok z Rozmberka (1539-1611) and his library

A recapitulation of the history of the the great library of the Bohemian statesman Peter Wok Rosenberg, which after his death entered the Emporor’s treasures in Prague, but was captured by the Swedish Army at the end of the Thirty Years War and brought to Stockholm, where parts still reside in the Royal Library. Its white bindings are a prominent feature of the Rosenberg collection.