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Probing molecules using perdeuteration (i.e deuteration in which all hydrogen atoms are replaced by deuterium) is extremely useful in a wide range of biophysical techniques. In the case of lipids, the synthesis of the biologically relevant unsaturated perdeuterated lipids is challenging and not usually pursued. In this work, perdeuterated phospholipids and sterols from the yeast Pichia pastoris gr
Trade Unions are finding it increasingly challenging to appeal to employees and all trade unions alike are encountering new challenges to attract and retain members. Additionally a more diversified and educated labor market is creating demands for trade unions to better meet individual needs. The purpose of this study was to explore and analyze the role of branding in Unionen, the largest white-co
Titel Livsstilsboenden - Processen kring att kombinera livsstil, service och boende Författare Elisa De Toro, Helene Tigerström & Liv Åström Handledare Cecilia Fredriksson & Örjan Hallgren Problem Det finns en stor mängd forskning inom områdena service, boende och livsstil. Dock ser vi att det saknas forskning kring hur dessa kan kombineras och hur processen kring detta ser ut. Syfte Syfte
Det finns många faktorer som påverkar hur svårlöst en konflikt är. Vi undersöker en av dem, nämligen skuggnätverken, genom att titta på kausalsambandet mellan skuggnätverk och staters olika uppbyggnadsprocesser. Begreppet skuggnätverk är en adaption av Nordstroms ?shadows? ? det vill säga ekonomiska och politiska länkar som på både lokal och internationell nivå rör sig utanför de statliga direktiv
Structured follow-up after revascularisation for chronic critical limb ischaemia (CLI) aims at sustained treatment success and continued best patient care. Thereby, efforts need to address three fundamental domains: (A) best medical therapy, both to protect the arterial reconstruction locally and to reduce atherosclerotic burden systemically; (B) surveillance of the arterial reconstruction; and (C
[FeFe]-hydrogenases are highly efficient H(2)-evolving metalloenzymes that include cyanides and carbonyls in the active site. The latter is an Fe(6)S(6) cluster (the so-called H-cluster) that can be subdivided into a binuclear portion carrying the CO and CN(-) groups and a tetranuclear subcluster. The fundamental role of cyanide ligands in increasing the basicity of the H-cluster has been highligh
Critical limb ischaemia (CLI) is a particularly severe manifestation of lower limb atherosclerosis posing a major threat to both limb and life of affected patients. Besides arterial revascularisation, risk-factor modification and administration of antiplatelet therapy is a major goal in the treatment of CLI patients. Key elements of cardiovascular risk management are smoking cessation and treatmen
Non-invasive vascular studies can provide crucial information on the presence, location, and severity of critical limb ischaemia (CLI), as well as the initial assessment or treatment planning. Ankle-brachial index with Doppler ultrasound, despite limitations in diabetic and end-stage renal failure patients, is the first-line evaluation of CLI. In this group of patients, toe-brachial index measurem
Efter den 11 september 2001 har det i väst blivit mer accepterat att göra negativa uttalanden om islam och muslimer i diskurser. Vår tes är att ledarsidorna i Jyllandsposten är ett exempel på en sådan diskurs där muslimer framställts som de Andra och ses som fundamentalt olika "danskarna". Syftet med denna studie är att undersöka diskursen om islam/muslimer på Jyllandspostens ledarsidor
An energy service company (ESCO) is an example of an atypical business concept that generates greater positive externalities as its business grows. The basic business concept of an ESCO is a company that installs energy efficient improvements in their customers' buildings, such as new lighting and ventilation systems, and then recovers expenditures and gains profits by splitting the resulting
Freeze damage is a common issue in many food items. The cellular dehydration caused by freezing can be prevented through addition of a cryoprotectant. Research has shown that it is possible to improve the freezing tolerance of plant materials by addition of cryoprotectants, which forms hydrogen bonds with water molecules. However, the cryoprotect needs to be in the cell to function. Which is where
Bakgrund: UNFPA är en underorganisation till Förenta Nationerna (FN). UNFPA fokuserar på populations- och utvecklingsstrategier och jämlikhet mellan könen. I mars 2005 bestämdes det i UNDP/UNFPAs styrelse att UNFPAs inköpsavdelning (PSB) skulle behöva förbättras om de skulle nå upp till sina mål. Flera studier har genomförts och resultatet av dessa visade bland annat på en rekommendation att införBackground: UNFPA is a subsidiary organ to the United Nations (UN) with a primary focus on population and development strategies, sexual and reproductive health and gender equality. In March 2005 the UNDP/UNFPA Executive Board had realized that for the UNFPA Procurement Services Branch (PSB) to operate in line with its mission, focus would need to be directed specifically towards improvements in t
Aim: Self-efficacy for writing is an important motivational factor and considered to predict writing performance. Self-efficacy for narrative writing has been sparsely studied, and few studies focus on the effects of writing intervention on self-efficacy. Additionally, there is a lack of validated measures of self-efficacy for elementary school students. In a previous study, we found that a traine
Thanks to an intensive technological effort in the framework of the EUFELE collaboration, the European FEL at ELETTRA was able to break the previous record for the shortest wavelength of an FEL oscillator. Novel solutions were adopted for multilayer mirrors to allow FEL operation in the wavelength region between 160 and 190 nm, which is one of the main targets of the project. The characteristics o
We present Gene-Aware Variant INterpretation (GAVIN), a new method that accurately classifies variants for clinical diagnostic purposes. Classifications are based on gene-specific calibrations of allele frequencies from the ExAC database, likely variant impact using SnpEff, and estimated deleteriousness based on CADD scores for >3000 genes. In a benchmark on 18 clinical gene sets, we achieve a sen
Objectives: Magnetic resonance spectroscopy (MRS) of children with or without neurometabolic disease is used for the first time for quantitative assessment of brain tissue lactate signals, to elaborate on previous suggestions of MRS-detected lactate as a marker of mitochondrial disease. Methods: Multivoxel MRS of a transverse plane of brain tissue cranial to the ventricles was performed in 88 chil
