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Adaptations for stealth in the wing-like flippers of a large ichthyosaur

With their superficially shark-like appearance, the Mesozoic ichthyosaurs provide a classic illustration of major morphological adaptations in an ancestrally terrestrial tetrapod lineage following the invasion of marine habitats1, 2–3. Much of what is known about ichthyosaur soft tissues derives from specimens with body outlines4, 5–6. However, despite offering insights into aspects of biology tha

Three-dimensional mapping of neurofibrillary tangle burden in the human medial temporal lobe

Tau protein neurofibrillary tangles are closely linked to neuronal/synaptic loss and cognitive decline in Alzheimer's disease and related dementias. Our knowledge of the pattern of neurofibrillary tangle progression in the human brain, critical to the development of imaging biomarkers and interpretation of in vivo imaging studies in Alzheimer's disease, is based on conventional two-dimensional his

Drug-Induced Epigenomic Plasticity Reprograms Circadian Rhythm Regulation to Drive Prostate Cancer toward Androgen Independence

UNLABELLED: In prostate cancer, androgen receptor (AR)-targeting agents are very effective in various disease stages. However, therapy resistance inevitably occurs, and little is known about how tumor cells adapt to bypass AR suppression. Here, we performed integrative multiomics analyses on tissues isolated before and after 3 months of AR-targeting enzalutamide monotherapy from patients with high

Maximally aligned states in Ag-99

Excited states of Ag-99 were populated via the Cr-50 + Ni-58 (261 MeV) reaction using the NORDBALL detector array equipped with charged-particle and neutron. detector systems for reaction channel separation. On the basis of the measured gammagamma-coincidence relations and angular distribution ratios a significantly extended level scheme has been constructed up to E-x similar to 7.8 MeV and I = 35

Maximum spin aligned states in Ag-98(47)51

New excited states have been observed in the neutron deficient isotope Ag-98 following the Ni-58+Cr-50-->Te-108* heavy-ion reaction. One of these states may be interpreted as a maximum spin aligned state of the pi g(9/2)(-3) nu vg(7/2) configuration. Other possible interpretations within the nuclear shell model are discussed as well.

Predictive molecular pathology in the time of coronavirus disease (COVID-19) in Europe

Aims Lung cancer predictive biomarker testing is essential to select advanced-stage patients for targeted treatments and should be carried out without delays even during health emergencies, such as the coronavirus (COVID-19) outbreak. Methods Fifteen molecular laboratories from seven different European countries compared 4 weeks of national lockdown to a corresponding period in 2019, in terms of t

Magnetic rotation in the 105Sn nucleus

The structure of 105Sn has been investigated through the 50Cr(58Ni,2pn) reaction at a beam energy of 210 MeV. In addition to an extension of the spherical level scheme a regular sequence of dipole transitions has been found. The states of the dipole band are suggested to be built on a neutron h2 11/2 excitation coupled to proton particle-hole states, which polarize the core to a slightly prolate s

European task force on atopic dermatitis position paper : treatment of parental atopic dermatitis during preconception, pregnancy and lactation period

Atopic dermatitis (AD) is a common inflammatory skin disease that affects both children and adults, including a large number of adults of reproductive age. Several guidelines for the treatment of AD exist, yet specific recommendations for the treatment of pregnant or lactating women and for adults planning to have a child are often lacking. This position paper from the European Task force on Atopi

Gaia Data Release 3 : Gaia scan-angle-dependent signals and spurious periods

Context. Gaia Data Release 3 (Gaia DR3) time series data may contain spurious signals related to the time-dependent scan angle. Aims. We aim to explain the origin of scan-angle-dependent signals and how they can lead to spurious periods, provide statistics to identify them in the data, and suggest how to deal with them in Gaia DR3 data and in future releases. Methods. Using real Gaia (DR3) data al

The course of health-related quality of life after the diagnosis of childhood cancer : a national cohort study

BACKGROUND: Comprehensive insight in the longitudinal development of health-related quality of life (HRQOL) after childhood cancer diagnosis could improve quality of care. Thus, we aimed to study the course and biopsychosocial determinants of HRQOL in a unique national cohort of children with cancer.METHODS: HRQOL of 2154 children with cancer was longitudinally reported (median: 3 reports) between

A method to identify barriers to and enablers of implementing climate change mitigation options

Mitigation option are not yet being implemented at the scale required to limit global warming to well below 2°C. Various factors have been identified that inhibit the implementation of specific mitigation options. Yet, an integrated assessment of key barriers and enablers is lacking. Here we present a comprehensive framework to assess which factors inhibit and enable the implementation of mitigati

Hydrogels derived from decellularized liver tissue support the growth and differentiation of cholangiocyte organoids

Human cholangiocyte organoids are promising for regenerative medicine applications, such as repair of damaged bile ducts. However, organoids are typically cultured in mouse tumor-derived basement membrane extracts (BME), which is poorly defined, highly variable and limits the direct clinical applications of organoids in patients. Extracellular matrix (ECM)-derived hydrogels prepared from decellula

Cost Effectiveness of Interval Cytoreductive Surgery With Hyperthermic Intraperitoneal Chemotherapy in Stage III Ovarian Cancer on the Basis of a Randomized Phase III Trial

Despite advancements in treatment modalities, the 10-year survival rate of women diagnosed with advanced-stage ovarian cancer has remained between 10% and 15% for the past 20 years. This is in part due to the majority of cases being diagnosed when disease has reached International Federation of Gynecology and Obstetrics stages III to IV. Approximately 70% of patients treated with cytoreductive sur

Comparison of histological delineations of medial temporal lobe cortices by four independent neuroanatomy laboratories

The medial temporal lobe (MTL) cortex, located adjacent to the hippocampus, is crucial for memory and prone to the accumulation of certain neuropathologies such as Alzheimer's disease neurofibrillary tau tangles. The MTL cortex is composed of several subregions which differ in their functional and cytoarchitectonic features. As neuroanatomical schools rely on different cytoarchitectonic definition

Longitudinal clinical and functional outcome in distinct cognitive subgroups of first-episode psychosis : A cluster analysis

Background Cognitive deficits may be characteristic for only a subgroup of first-episode psychosis (FEP) and the link with clinical and functional outcomes is less profound than previously thought. This study aimed to identify cognitive subgroups in a large sample of FEP using a clustering approach with healthy controls as a reference group, subsequently linking cognitive subgroups to clinical and

PXK locus in systemic lupus erythematosus: fine mapping and functional analysis reveals novel susceptibility gene ABHD6

Objectives To perform fine mapping of the PXK locus associated with systemic lupus erythematosus (SLE) and study functional effects that lead to susceptibility to the disease. Methods Linkage disequilibrium (LD) mapping was conducted by using 1251 SNPs (single nucleotide polymorphism) covering a 862 kb genomic region on 3p14.3 comprising the PXK locus in 1467 SLE patients and 2377 controls of Euro

Lundgren karin thesis 2010

A study of the capacity building programmes following the Stockholm Convention on Persistent Organic Pollutants (POPs) Capacity Building for Sustainability? An evaluation study of the capacity building programmes following the Stockholm Convention on Persistent Organic Pollutants (POPs). Author: Karin Lundgren E-mail: karin.maria.lundgren@gmail.com Thesis Supervisor: Anna-Karin Bergman, LUCSUS A m

https://www.lumes.lu.se/sites/lumes.lu.se/files/lundgren_karin_thesis_2010.pdf - 2026-05-07

2024 VT_LP2 FMSF65 CEQ Course evaluation ver 9.0 (2021-01-23) LTH

2024 VT_LP2 FMSF65 CEQ Course evaluation ver 9.0 (2021-01-23) LTH Course evaluation report - CEQ, FMSF65 Basic facts Course name Design of Experiments Course code FMSF65 ECTS credits 7.5 hp Year 202324 Study period the course was finishedVT_LP2 Programme all (W) Registrated students 31 Number answers and response rate 8 / 26 % Number answers from males 3 Number answers from females 2 Study hours a

https://www.maths.lu.se/fileadmin/maths/utbildning_education/Kursutv_VT24/FMSF65_2024_VT_LP2_arbetsrapport_en.pdf - 2026-05-04

Tentacle

Written by Jens Hylander, 24 March 2020 Tentacle by Rita Indiana is a short novel, but don’t judge a book by its page numbers. The 130 pages is thick with social commentary and cultural references stacked on top of each other to reach so high it is hard to overlook. It took me almost one hundred pages to actually grasp the story, and even then, I was left wondering about many things. In this sense

https://www.climatefutures.lu.se/climate-fiction/reflections-climate-fictions/tentacle - 2026-05-05

About

We have expertise in research on alternative organising, political economy, and plastic policy and governance. “Plastics in a circular society: Alternative organising beyond resource efficiency” brings together an international interdisciplinary team of researchers from Lund University, Copenhagen Business School, and Geneva Graduate Institute. It is funded by Formas (the Swedish Research Council

https://www.plasticalternatives.lu.se/about - 2026-05-05