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Objectives: This is a protocol for a Cochrane Review (intervention). The objectives are as follows:. To determine the benefits and harms of opioid analgesics in neonates (term or preterm) receiving mechanical ventilation, compared to placebo, no drug, other opioids, other analgesics or sedatives.
DMe-DCNQI forms highly-ordered ultrathin films on various single crystal surfaces. NEXAFS reveals flat lying molecules for all investigated film thicknesses (up to 40 layers) on nearly all substrates under investigation (Ag(111), Ag(100), Cu(100), Cu(111)). The C1s and N1s NEXAFS spectra of these condensed layers show several very sharp resonances. The comparison with the quinoide molecules TCNQ a
Aim: Students with hearing loss (HL) often fall behind hearing peers in complex language tasks such as narrative writing. This study explored the effects of school grade, gender, cognitive and linguistic predisposition and audiological factors on narrative text quality in this target group.Method: Eleven students with HL in Grades 5–6 and 7–8 (age 12–15) who took part in a writing intervention wro
We establish an exactly tight relation between reversiblepebblings of graphs and Nullstellensatz refutations of pebbling formulas,showing that a graph G can be reversibly pebbled in time t and space s if and only if there is a Nullstellensatz refutation of the pebbling formulaover G in size t + 1 and degree s (independently of the field in whichthe Nullstellensatz refutation is made). We use this
Introduction Systemic sclerosis (SSc) is a chronic, autoimmune connective tissue disease associated with high morbidity and mortality, especially in diffuse cutaneous SSc (dcSSc). Currently, there are several treatments available in early dcSSc that aim to change the disease course, including immunosuppressive agents and autologous haematopoietic stem cell transplantation (HSCT). HSCT has been ado
Using satellite remote sensing data for observing vegetation seasonality is an important approach to estimate phenology and carbon uptake of land vegetation. The successful launch of Sentinel-2B in 2017 initiated full operation of the Sentinel-2 twin satellites, and they now provide 10 - 60 m spatial resolution satellite data at 5 days temporal resolution worldwide, releasing approximately 3.2 TB
BACKGROUND: We previously observed decreasing resection rates of non-metastatic gastric adenocarcinoma (GaC) in the US and some European countries. If and to what extent these trends affect the trends in overall survival (OS) of patients with non-metastatic GaC at the population level remain unclear. This large international population-based cohort study aimed to assess the impact of the previousl
Previous studies have identified a range of transcription factors that modulate retrograde regulation of mitochondrial and chloroplast functions in Arabidopsis (Arabidopsis thaliana). However, the relative importance of these regulators and whether they act downstream of separate or overlapping signaling cascades is still unclear. Here, we demonstrate that multiple stress-related signaling pathway
Targeted quantitative mass spectrometry of immunoaffinity-enriched peptides, termed immuno-multiple reaction monitoring (iMRM), is a powerful method for determining the relative abundance of proteins in complex mixtures, like plasma or whole tissue. This technique combines 1,000-fold enrichment potential of antibodies for target peptides with the selectivity of multiple reaction monitoring mass sp
The rheology of dense granular flows is studied numerically in a shear cell controlled at constant pressure and shear stress, confined between two granular shear flows. We show that a liquid state can be achieved even far below the yield stress, whose flow can be described with the same rheology as above the yield stress. A non-local constitutive relation is derived from dimensional analysis throu
The recently funded, five-year, project Melody in Human–Cat Communication (Meowsic) has received vast media attention, both nationally and around the world. In this paper we summarize how our activities got started, our published results so far, the present situation and how we envision our planned, future research, including some of the core hypotheses to be addressed by the project.
We describe a case of an adolescent male with Niemann-Pick Type C (NP-C), a neurodegenerative lysosomal lipid storage disorder, who presented with recurrent catatonia which required repeated treatment with electroconvulsive therapy (ECT). During the ECT-course, seizure threshold increased substantially, leading to questions about the influence of NP-C on neuronal excitability. In this exemplary EC
A well-known property of sexual selection combined with a cross-sex genetic correlation (rmf) is that it can facilitate a peak shift on the adaptive landscape. How do these diversifying effects of sexual selection + rmf balance with the constraints imposed by such sexual antagonism, to affect the macroevolution of sexual dimorphism? Here, I extend existing quantitative genetic models of evolution
Complement factor I (FI) is a central inhibitor of the complement system, and impaired FI function increases complement activation, contributing to diseases such as age-related macular degeneration (AMD) and atypical hemolytic uremic syndrome (aHUS). Genetic variation in complement factor I (CFI) has been identified in both AMD and aHUS, with more than half of these variants leading to reduced FI
BACKGROUND AND PURPOSE: In total knee arthroplasty (TKA), metal-backed (MBT) and all-polyethylene (APT) designs have shown comparable implant migration up to 2 years postoperatively using radiostereometric analysis (RSA). However, studies comparing mid-term migration of both designs are lacking. Furthermore, continuously migrating TKAs up to 2 years may continue to migrate or stabilize thereafter
Every day we make choices, but our degree of investment in them differs, both in terms of pre-verbal experience and verbal justification. In an earlier experimental study, participants were asked to pick the more attractive one among two human faces, and among two abstract figures, and later to provide verbal motivations for these choices. They did not know that in some of the cases their choices
Microsoft Word - COSM34 2020 Schedule (2020.11.16).docx 1 COSM34 Development Theories and Issues in Asia Autumn Semester 2021 Course director: Nicholas Loubere E-mail: Nicholas.loubere@ace.lu.se Period: 1 November – 30 November 2021 Office hours: By appointment Teaching 9 Lectures 2 Seminars Readings Students are required to complete all the required readings prior to class. Students, in groups, a
https://www.ace.lu.se/sites/ace.lu.se/files/2021-10/COSM34_Schedule_2021.pdf - 2026-07-02
