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The present series comprises all families (n = 77) with haemophilia B in Sweden and may be considered to be representative for the purposes of a population-based study of mutational heterogeneity. The 77 families (38 severe, 10 moderate, 29 mild) had 51 different mutations in total. Thirteen families had total, partial or small deletions, two had mutations in the promoter, eight families had splic
Bactericidal/permeability-inereasing protein (BPI) neutralizes the proinflammatory effects of lipopolysaccharide and is of potential clinical use in the treatment of fulminant Gram-negative infections. BPI is a cationic protein with antibacterial activity stored in azurophil (primary) granules of neutrophil granulocytes. However, the absence of BPI in patients with specific granule deficiency indi
SPECT projections are contaminated by scatter, resulting in reduced image contrast and quantitative errors. When tissue is present behind the source, some of the detected photons backscatter via this tissue. Particularly in dual-isotope SPECT and in combined emission-transmission SPECT, backscatter constitutes a major part of the down-scatter contamination in lower-energy windows. In this paper, t
The paper presents a fed-batch fermentation technique for bioreactors operating close to their maximum oxygen transfer capacity. The method combines the advantages of the probing feeding strategy and the temperature limited fed-batch technique. When the maximum oxygen transfer capacity of the reactor is reached, the temperature is decreased to lower the oxygen demand. To achieve a good control of
The most frequently used model to describe the exponential increase in mortality rate over age is the Gompertz equation. Logarithmically transformed, the equation conforms to a straight line, of which the slope has been interpreted as the rate of senescence. Earlier, we proposed the derivative function of the Gompertz equation as a superior descriptor of senescence rate. Here, we tested both measu
Popular Abstract in SwedishMed utgångspunkt i två forskningsfält – strategisk kommunikation och urbanforskning – analyseras och problematiseras Malmös omvandling från arbetarstad till kunskapsstad. Hur har Malmös förändring genomdrivits? Vilka resonemang och föreställningsramar har styrt omvandlingen? Vilka kommunikativa strategier har använts för att projicera den önskvärda (själv)bilden av en ku
Abstract Pseudomonas aeruginosa is often found in chronic infections, including cystic fibrosis lung infections and those related to chronic wounds and venous ulcers. At the latter sites, P. aeruginosa can be isolated together with Staphylococcus epidermidis, and we have therefore explored the effect of clinical isolates and laboratory strains of P. aeruginosa strains on colonization by S. epiderm
A report from the conference Post-Colonialism and Global Migration and the exhibition Inclusion/Exclusion held in Graz, Austria, in 1997.
Popular Abstract in Swedish Västeuropeiska stater har blivit alltmer mångkulturella. Migrationsflöden från fattigare delar av välden har bidragit till att länder som tidigare uppfattade sig själva som homogena, uppvisar en allt högre grad av kulturella, etniska och religiösa olikheter. Förespråkare för mångkulturalism har argumenterat att ett sätt att hantera gruppers olikheter är att tolerera der
Aims: Differences in morphology in adult barn swallows were investigated using bone and feather measurements taken from birds from a northern (Danish) and a southern (Spanish) European population. Discriminant Function Analysis was used to help in discriminating the sex of individuals of both populations. Location: Badajoz (Spain) and Kraghede (Denmark). Methods: Two discriminant functions were ob
The release of two compositionally different solutes from a composite gel composed of two different populations of microgel particles embedded in a single bulk gel matrix is described, showing the potential of the "plum-pudding gel" as a multifunctional platform for controlled surface release. One hydrophobic solute (pyrene) and one hydrophobic and charged solute (rhodamine 123) were chosen as the
Crosslinking of small heat-shock proteins (sHsps) by tissue transglutaminase (tTG) is enhanced by stress and under pathological conditions. We here used hexapeptide probes to determine the amine donor (K) and acceptor (Q) sites for tTG in Hsp20. Mass spectrometric peptide mass fingerprinting and peptide fragmentation established that Q(31) and the C-terminal K-162 are involved in inter- and intram
Although trisomy 8 as a sole change is one of the most common chromosomal abnormalities in myeloid malignancies, it is largely unknown if the incidence of this aberration is influenced by other factors of clinical importance. In the present study, the frequencies of isolated +8 in relation to gender, age, previous treatment with chemo- or radiotherapy, and morphologic subtype were ascertained in p
Denna uppsats handlar om hänförbarhet av handlande under fredsbevarande insatser. Uppsatsen försöker redogöra för hur hänförbarhet går till enligt in-ternationell sedvanerätt. Detta har gjorts genom att tillämpa rättsdogmatisk metod. För att utreda den internationella sedvanerätten har jag inledningsvis undersökt ILCs instrument DARIO och ARSIWA och dess betydelse på om-rådet. Sedan har jag undersThis essay focuses on attribution of conduct in peacekeeping missions. The study attempts to explain how attribution is carried out according to interna-tional customary law, through legal dogmatic method. To investigate interna-tional customary law, I initially examined the ILC’s instruments DARIO and ARSIWA, and their impact in this area. The study goes on to examine the significance of these in
This thesis explores the discursive depiction of life in Portugual from the perspective of lifestyle migrants and digital nomads on TikTok. The aim of this thesis is to uncover the motivations of foreigners to live in Portugal, lifestyle migrants’ integration into Portuguese society, and their acknowledgement of the growing gentrification issues in Portugal. The method used in this study is Norman
Cultural tourism and cultural heritage management, while distinct disciplines with differing foci, are also inherently intertwined. However, conflicts between the two often arise due to the diverse number of stakeholders and interests involved in either the travel industry or the conservation and protection of cultural heritage. Despite this, cultural tourism can greatly benefit the conservation o
Electricity finds itself different from other fresh-ware commodities, it cannot easily be stored. This characteristic trait of electricity results in traditional pricing methods not working for electricity pricing. Thus different pricing schemes are needed, such as Price Forward Curves (PFC) or pricing against a price level. The price forward curves are constructed through a mix of historical mark
The idea of Chile as a “miracle” of neoliberal reform has been extensively confronted since October of 2019 in a large wave of protests throughout the country, by a vast majority feeling excluded from its benefits. Despite this conflict (known as the “Estallido Social”, or “Social Outbreak”) occurring exclusively in cities, previous analyses do not explicitly address the role of urban space in thi
The many advantageous abilities of plastics have made them omnipresent in today’s society. However, the low cost of production, light weight, durability and insolubility in water combined with inadequate waste handling have led to a vast and increasing accumulation of plastics in nature, approximated to be over 6 300 million tons (Geyer, Jambeck and Law, 2017, ‘Production, use, and fate of all pla
