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BACKGROUND: Radiostereometric analysis (RSA) is a highly accurate tool to detect implant migration and predict loosening following total knee arthroplasty (TKA). However, little is known about the predisposing risk factors for implant migration, nor which migration profile should be considered physiological (i.e., merely part of an implant-settling phase) and which should be considered pathologica

The Rodinia supercontinent broke apart during the Neoproterozoic. Rodinia break-up is associated with widespread intraplate magmatism on many cratons, including the c. 720–719 Ma Franklin large igneous province (LIP) of Laurentia. Coeval magmatism has also been identified recently in Siberia and South China. This extensive magmatism terminates ∼1 myr before the onset of the Sturtian Snowball Earth

BACKGROUND: Per-and polyfluoroalkyl substances (PFAS) are widespread and persistent pollutants that have been associated with elevated cholesterol levels. However, data on incident cardiovascular disease (CVD) is lacking. OBJECTIVES: We investigated the association of exposure to PFAS with risk of myocardial infarction and stroke and, subsidiary, with baseline blood lipids. METHODS: This populatio

The current paper presents the results of behavioural observations in a field experiment with automated shuttles in Oslo, Norway. Video observations were conducted at five fixed locations along a challenging 1.2 km automated shuttle line with varying traffic conditions. Observed interactions between vulnerable road users and automated shuttles were coded using a predefined codebook, which allowed

The unprecedented scale of the Covid-19 pandemic has been a challenge for health supply chains around the world. Many international humanitarian organizations have had to ensure the continuity of their already complex development programs, while addressing their supply chain disruptions linked to the pandemic. Process modularity has frequently been advocated as a strategy to mitigate such disrupti

The technological push for hydrogen-based steel production has become a flagship project of the Swedish state for advancing its global environmental leadership and becoming the world's first fossil free welfare state. The new production process has the potential to drastically cut emissions in a heavy polluting industry. The plans also entail a drastic upscale in steel production, energy and iron

This article presents the results of groundwater monitoring over a period of six years and the interpretation of these results by a reactive transport model, following an In Situ Recovery (ISR) test on the Dulaan Uul uranium deposit in Mongolia. An environmental monitoring survey was set up using 17 piezometers, from which it has been possible to describe the changes in the water composition befor

Prognostic tools are an essential component of the clinical management of patients with renal cell carcinoma (RCC). Although tumour stage and grade can provide important information, they fail to consider patient- and tumour-specific biology. In this study, we set out to find a novel molecular marker of RCC by using hepatocyte nuclear factor 4A (HNF4A), a transcription factor implicated in RCC pro

How can we create sustainable agriculture, capable of feeding the soon to be 10 billion people of the earth, and at the same time preserve the ecosystems of the species that coexist with us on this planet? A team from Lund University in Sweden attempts to answer this tricky question.

Conventional surveillance systems are omnipresent and most are still based on analog techniques. Migrating to the digital domain grants access to the world of digital image processing enabling automation of such systems, which means extracting information from the image stream without human interaction. The resolution, frame rates, and functionality in these systems are continuously increasing alo

Background: Hyperthyroidism is a rare disorder which may negatively affect health and quality of life. Its occurrence in childhood cancer survivors has not previously been investigated in detail. Material and methods: In the hospital registers of the five Nordic countries, 32,944 childhood cancer survivors and 212,675 population comparisons were followed for the diagnosis of hyperthyroidism. Hospi

A recombinant Baeyer-Villiger monooxygenase, BVMO4 from Dietzia sp. D5 has been previously reported. The enzyme exhibited good thermostability and was active with a wide range of cyclic ketone substrates but catalysed poorly the conversion of cyclohexanone to caprolactone. The present work focuses on protein engineering of BVMO4 to improve the conversion of cyclohexanone. Thus, a structural model

The wide variety of molecular architectures used in sensors and biosensors and the large amount of data generated with some principles of detection have motivated the use of computational methods, such as information visualization techniques, not only to handle the data but also to optimize sensing performance. In this study, we combine projection techniques with micro-Raman scattering and atomic

GaAs nanowire arrays on silicon offer great perspectives in the optoelectronics and solar cell industry. To fulfill this potential, gold-free growth in predetermined positions should be achieved. Ga-assisted growth of GaAs nanowires in the form of array has been shown to be challenging and difficult to reproduce. In this work, we provide some of the key elements for obtaining a high yield of GaAs

The objective of this study is to explore mechanisms for ignition and extinction for condensed-phase fuels via the use of a gas-fueled burner. Flames were generated with a porous 25 mm circular burner using mixtures of methane and propane with nitrogen. The procedure was to specify a set of mass fluxes of nitrogen-fuel mixture that corresponded to the flash- fire- and extinction points and for the

Background: Poly-3-d-hydroxybutyrate (PHB) that is a promising precursor for bioplastic with similar physical properties as polypropylene, is naturally produced by several bacterial species. The bacterial pathway is comprised of the three enzymes β-ketothiolase, acetoacetyl-CoA reductase (AAR) and PHB synthase, which all together convert acetyl-CoA into PHB. Heterologous expression of the pathway