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The evolution and maintenance of color clines is a classic topic of research in evolutionary ecology. However, studies analyzing the temporal dynamics of such clines are much less frequent, due to the difficulty of obtaining reliable data about past color distributions along environmental gradients. In this article, we describe a case of decades-long temporal stability and directional change in a
Simultaneous rheological, polarized light imaging, and small-angle X-ray scattering experiments (Rheo-PLI-SAXS) are developed, thereby providing unprecedented level of insight into the multiscale orientation of hierarchical systems in simple shear. Notably, it is observed that mesoscale alignment in the flow direction does not develop simultaneously across nano-micro lengthscales in sheared suspen
Stimuli-responsive polymers stand out for their ability to respond to small environmental changes. One of the most representative thermo-sensitive materials is poly(N-isopropyl acrylamide) (PNIPAm), which presents reversible phase transitions close to the human body temperature. However, previous studies observed that the copolymerization of NIPAm with small quantities of different monomers like a
iiAbstractThis thesis examines how women living in a women-only asylum shelter in Austria exercise agency in their daily lives amid institutional regulation, legal uncertainty, and prolonged waiting. It explores how residents organise their daily lives, cope with insecurity, and try to maintain a sense of control within institutional settings and social relationships. Agency is not understood as a
Microsoft Word - 68284559-file00 10.1101/gr.147678.112Access the most recent version at doi: published online December 10, 2012Genome Res. Helen M Rowe, Adamandia Kapopoulou, Andrea Corsinotti, et al. cells necessary to preserve transcriptional dynamics in embryonic stem TRIM28 repression of retrotransposon-based enhancers is P
https://www.molecular-neurogenetics.lu.se/sites/molecular-neurogenetics.lu.se/files/full_article.pdf - 2026-07-06
European countries have been receiving refugee children for decades with a recent peak in 2015/2016 (Crul 2017). Although the number of refugees currently arriving in Europe must be seen in proportion to the much higher percentage of refugees that remain in states outside European borders (Dryden-Peterson 2016), the inclusion of refugee children is perceived as a major challenge by policy makers a
A firm understanding of the coupling between the deformation on different scales within a material is key when formulating multi-scale constitutive models. In many polymers, the macroscopic deformation is, to a large extent, dictated by the underlying molecular structure and how this evolves during loading. To gain information ab out the behaviour of the molecular structure during deformation, non
The nervous system is engaged by infection, indirectly through inflammatory cascades or directly, by bacterial attack on nerve cells. Here we identify a neuro-epithelial activation loop that participates in the control of mucosal inflammation and pain in acute cystitis. We show that infection activates Neurokinin-1 receptor (NK1R) and Substance P (SP) expression in nerve cells and bladder epitheli
Drought in Australia has widespread impacts on agriculture and ecosystems. Satellite-based Fraction of Absorbed Photosynthetically Active Radiation (FAPAR) has great potential to monitor and assess drought impacts on vegetation greenness and health. Various FAPAR products based on satellite observations have been generated and made available to the public. However, differences remain among these d
The ability of B-1 cells to become positively selected into the mature B cell pool, despite being weakly self-reactive, has puzzled the field since its initial discovery. Here, we explore changes in B cell positive selection as a function of developmental time by exploiting a link between CD5 surface levels and the natural occurrence of self-reactive B cell receptors (BCRs) in BCR wild-type mice.
The determination of the net charge and size of microgel particles as a function of their concentration, as well as the degree of association of ions to the microgel backbone, has been pursued in earlier studies mainly by scattering and rheology. These methods suffer from contributions due to inter-particle interactions that interfere with the characterization of single-particle properties. Here w
Microencapsulation by spray drying of oil-in-water (o/w) emulsions provides a means to encapsulate functional lipophilic ingredients. The active ingredient is dispersed in continuous solid phase providing protection. However, the encapsulation efficiency depends on the microstructure and morphology of the dry particles influenced by several mechanisms occurring during processing such as oil drople
Contactin genes CNTN5 and CNTN6 code for neuronal cell adhesion molecules that promote neurite outgrowth in sensory-motor neuronal pathways. Mutations of CNTN5 and CNTN6 have previously been reported in individuals with autism spectrum disorders (ASDs), but very little is known on their prevalence and clinical impact. In this study, we identified CNTN5 and CNTN6 deleteriousvariants in individuals
Expression of antibodies inside cells has been used successfully to ablate protein function. This finding suggests that the technology should have an impact on disease treatment and in functional genomics where proteins of unknown function are predicted from genomic sequences. A major hindrance is the paucity of antibodies that function in eukaryotic cells, presumably because the antibodies fold i
