Filtyp
Density-gradient centrifugation of bovine tracheal epithelial cell extracts revealed a 'high-density' (1.48 g/ml) sialic-acid-rich population as well as a 'low-density' (1.42 g/ml) one that reacted more strongly with a periodate-Schiff (PAS) assay. The sialic-acid-rich mucins were oligomeric molecules containing disulphide-bond-linked subunits and large glycosylated domains, whereas the PAS-reacti
Excitatory amino acids are implicated in the development of neuronal cell damage following periods of reversible cerebral ischemia or insulin-induced hypoglycemic coma. To explore the importance of glutamate receptor activation in the posthypoglycemic phase, we exposed rats to 20 min of insulin-induced severe hypoglycemia. The rats were treated immediately after the hypoglycemic insult with four r
The effect of different glutamate‐receptor antagonists on the induction of cortical spreading depression of Leao and of cortical anoxic membrane depolarization were investigated in the anaesthetized rat. Spreading depression (SD), elicited by mechanical stimulation of the cortical surface, was inhibited by the non‐competitive N‐methyl‐d‐aspartate (NMDA)‐receptor blocker, (±)‐5‐methyl‐10,11‐dihydro
Acute myeloid leukemia (AML) with t(9;22)(q34;q11), also known as AML with BCR-ABL1, is a rare, provisional entity in the WHO 2016 classification and is considered a high-risk disease according to the European LeukemiaNet 2017 risk stratification. We here present a retrospective, population-based study of this disease entity from the Swedish Acute Leukemia Registry. By strict clinical inclusion cr
Background: Baleen whales are a clade of gigantic and highly specialized marine mammals. Their genomes have been used to investigate their complex evolutionary history and to decipher the molecular mechanisms that allowed them to reach these dimensions. However, many unanswered questions remain, especially about the early radiation of rorquals and how cancer resistance interplays with their huge n
This thesis examines the role of beamlines with publication metadata from the European Synchrotron Radiation Facility (ESRF a large scientific facility offering diverse conditions for scientific research. As a user-oriented Big Science facility, the ESRF channels extremely brilliant light into different experimental areas called beamlines that house specific instruments that cater to the needs of
Purpose: Etoposide to standard R-CHOP is used for high-risk diffuse large B-cell lymphoma (DLBCL) in some countries. Due to the lack of randomized trials, a real-world data study using matching methods was used to test the potential effectiveness of R-CHOEP over R-CHOP. Patients and Methods: This study included patients from the Danish Lymphoma Register diagnosed between 2006 and 2020 at the age o
Rubella virus encodes a nonstructural polyprotein with RNA polymerase, methyltransferase, and papain-like cysteine protease activities, along with a putative macrodomain of unknown function. Macrodomains bind ADP-ribose adducts, a post-translational modification that plays a key role in host-virus conflicts. Some macrodomains can also remove the mono-ADP-ribose adduct or degrade poly-ADP-ribose ch
Abstract in DanishLars-Johan Ekerots bog om svensk som andetsprog foreligger nu i dansk oversættelse og med et noteapparat henvendt til dansksprogede læsere.Bogen har siden udgivelsen i 1995 været et standardværk på læreruddannelser og andre uddannelser i svensk i Sverige og Finland samt på kurser i svensk som fremmedsprog.Bogen har også længe været flittigt brugt af studerende og kommende undervi
Background. Primary glomerular disease (PGD) is a major cause of end-stage kidney disease (ESKD) leading to kidney replacement therapy (KRT). We aimed to describe incidence (trends) in individuals starting KRT for ESKD due to PGD and to examine their survival and causes of death. Methods. We used data from the European Renal Association (ERA) Registry on 69 854 patients who started KRT for ESKD du
Background: Fentanyl is commonly administered for procedural pain management in preterm infants, but target concentrations have not yet been defined. Methods: To investigate pharmacokinetics (PK), -dynamics (PD), and -genetics (PG), 25 infants (gestational age 23.3–34.1 weeks) received a fentanyl dose before a skin-breaking procedure (0.5 µg/kg) or tracheal intubation (2 µg/kg). Four pain scales w
We live in a time where capitalism has long since eliminated any notion of alternative systems from our imaginaries, so that it “occupies the horizon of the thinkable” (Fisher 2009). At the same time, we have seen a (re)turn to positivism and acceptance of the neoliberal system in academia, even in the humanities and studies of art (Grønstad 2020, Poenar 2018). The rejection of the political proje
This thesis paper studies the organic legislative framework in the European Union. It describes how the EU organic regulation has developed and discusses the future trends, issues and opportunities of the organic movement. It researches how organic is regulated in the EU today, what its’ objectives and aims are, what issues and improvement exist and how the organic movement will develop in the fut
The genus Caldicellulosiruptor and especially Caldicellulosiruptor saccharolyticus are gaining attention because of their potential as biohydrogen producers from agricultural and forestry waste on an industrial scale. Genetic and in turn metabolic engineering can be used to aid in the characterization of C. saccharolyticus. Additionally, it can be used in strain improvement to overcome limiting fa
Syftet med föreliggande masteruppsats är att redogöra för och analysera rätten att vidta stridsåtgärder samt föreningsfrihet, i synnerhet i situationer då arbetsgivaren redan är bunden av kollektivavtal. I huvudsak kommer tre perspektiv att tillämpas; ett internationellt, ett nationellt samt ett med användande av den pågående konflikten i Göteborgs hamn. För att uppnå syftet har en rättsdogmatisk The aim of the thesis is to analyse the right to undertake industrial actions and freedom of association, especially in the case where a collective agreement already is in place. The thesis applies mainly three perspectives: a national, an international and lastly one with the concrete use of the ongoing conflict in the port of Gothenburg. To achieve the aim a legal dogmatic method is applied. T
This project addresses the problems the traditional loom has in our modern so- ciety resulting in a product that provides a new and modernized way of looking at the loom. A lighter, easier and more intuitive version that one could use even without having previous experience with weaving. Most of us have an encountered a loom in our lives, but very few have a relationship to it. As weaving is one
The threat of potentially catastrophic climate change has led to 195 countries pledging to keep global average temperature rise well below 2°C based on pre-industrial levels. Wind energy technology has developed to a point where it can make a significant contribution to meeting this objective. A number of countries have developed substantial wind energy networks in recent years which in turn has a
Idrottsrörelsen med fotboll i fokus har kommit att förändra sin struktur avsevärt under 1900-talet. Fotbollen har gått från att vara en ideell verksamhet med syfte att samla de lokala invånarna för att utöva sporten till en miljardindustri inom Europa. EU:s konkurrensregler har kommit att spela en viktig roll för att främja idrottens utveckling samt förhindra att marknaden snedvrids genom ekonomisSport movement especially football has change its structure of the sport drastically during the 20th century. Football has transformed from being a non-profit activity with one of its purpose to gather the locals for a friendly game to a multibillion industry within Europe. EU: s competition law has played a crucial part to maintain the development for sport and to prevent distortion of competitio
