Filtyp
Since the publication of the European League Against Rheumatism recommendations for the pharmacological treatment of psoriatic arthritis (PsA) in 2012, new evidence and new therapeutic agents have emerged. The objective was to update these recommendations.
Den s.k. sexköpslagen (1998:408) trädde ikraft år 1999. Efter en översyn av sexualbrottsbestämmelserna, fördes den 1 april förbudet av sexköp in i 6 kap. 11 § BrB (SFS 2005:90). Bakgrunden till kriminaliseringen är att prostitution av lagstiftaren definieras som våld mot kvinnor. Prostitution beskrivs inte kunna vara frivillig och genom förbudets införande fokuserades på mäns efterfrågan, en grupp
Uppsatsen behandlar svenska internationella privat- och processrättsliga (IP-rätt) frågor rörande den svenska kollektiva arbetsrätten, varmed förstås den relation mellan arbetsgivare och fackförening samt de tvister som därur kan uppstå. Huvudfrågorna är de som traditionellt anses utgöra den IP-rättsliga problematiken, vilka utgörs av jurisdiktionsfrågan, lagvalsfrågan och verkställighetsfrågan. JThis thesis addresses a private international law perspective of questions and problems related to cross-border collective labour law disputes in Sweden. This means, in Swedish terminology1, that the researched issues are the questions of jurisdiction, choice of law and enforceability in disputes arising from the relation between an employer and a workers' union. Collective labour law in Swede
Uppsatsen behandlar bankernas bristtäckningsansvar vid otillåtna vinstutbetalningar. Rättsläget har under många år varit osäkert och omtvistat men genom NJA 1997 s. 418 skedde ett klarläggande. Intresset att upprätthålla kapitalskyddet ställdes mot hänsynen till omsättningens säkerhet och det praktiska ekonomiska livet. Med öppen vinstutbetalning menas att utbetalningen till aktieägare betecknas s
Since the signing of the Treaty on the European Union (TEU) in 1993 the European Union has been base on three "&semicpillars"&semic. The European Community falls under the so-called pillar I. Under the terms of the TEU the two pillars on the Common Foreign and Security Policy (CFSP) and on Justice and Home Affairs (JHA) differ from pillar I for they do not share the institu
We present the abundance analysis for a sample of 7 red giant branch stars in the metal-poor globular cluster NGC 4372 based on UVES spectra acquired as part of the Gaia-ESO Survey. This is the first extensive study of this cluster from high-resolution spectroscopy. We derive abundances of O, Na, Mg, Al, Si, Ca, Sc, Ti, Fe, Cr, Ni, Y, Ba, and La. We find a metallicity of [Fe/H] = -2.19 +/- 0.03 an
One of the most stress-responsive genes encoding a mitochondrial protein in Arabidopsis (At3g50930) has been annotated as AtBCS1 (cytochrome bc1 synthase 1), but was previously functionally uncharacterised. Here, we show that the protein encoded by At3g50930 is present as a homo-multimeric protein complex on the outer mitochondrial membrane and lacks the BCS1 domain present in yeast and mammalian
Plants require daily coordinated regulation of energy metabolism for optimal growth and survival and therefore need to integrate cellular responses with both mitochondrial and plastid retrograde signaling. Using a forward genetic screen to characterize regulators of alternative oxidase1a (rao) mutants, we identified RAO2/Arabidopsis NAC domain-containing protein17 (ANAC017) as a direct positive re
Tamoxifen therapy resistance constitutes a major cause of death in patients with recurrent estrogen receptor (ER) positive breast cancer. Through high resolution mass spectrometry (MS), we previously generated a 4-protein predictive signature for tamoxifen therapy outcome in recurrent breast cancer. ANXA1 and CALD1, which were not included in the classifier, were however the most differentially ex
This report was prepared in the context of the LPCC Electroweak Precision Measurements at the LHC WG (https://lpcc.web.cern.ch/lpcc/index.php?page=electroweak_wg) and summarizes the activity of a subgroup dedicated to the systematic comparison of public Monte Carlo codes, which describe the Drell–Yan processes at hadron colliders, in particular at the CERN Large Hadron Collider (LHC). This work re
Scope: To explore the effect of a healthy Nordic diet on the global transcriptome profile in peripheral blood mononuclear cells (PBMCs) of subjects with metabolic syndrome. Methods and results: Subjects with metabolic syndrome undergo a 18/24 week randomized intervention study comparing an isocaloric healthy Nordic diet with an average habitual Nordic diet served as control (SYSDIET study). Altoge
The search for a method that utilizes biological information to predict humans' place of origin has occupied scientists for millennia. Over the past four decades, scientists have employed genetic data in an effort to achieve this goal but with limited success. While biogeographical algorithms using next-generation sequencing data have achieved an accuracy of 700 km in Europe, they were inaccurate
Capillaroscopy is a non-invasive and safe tool which allows the evaluation of the morphology of the microcirculation. Since its recent incorporation in the 2013 American College of Rheumatology (ACR)/European League Against Rheumatism (EULAR) classification criteria for systemic sclerosis together with its assessed role to monitor disease progression, capillaroscopy became a ‘mainstream’ investiga
The interaction of antikaons with nucleons and nuclei in the low-energy regime represents an active research field in hadron physics with still many important open questions. The investigation of light kaonic atoms is, in this context, a unique tool to obtain precise information on this interaction. The most precise kaonic hydrogen measurement to date, together with an exploratory measurement of k
Background: Niemann-Pick disease type C (NP-C) is a rare, inherited neurodegenerative disease of impaired intracellular lipid trafficking. Clinical symptoms are highly heterogeneous, including neurological, visceral, or psychiatric manifestations. The incidence of NP-C is under-estimated due to under-recognition or misdiagnosis across a wide range of medical fields. New screening and diagnostic me
PURPOSE: To document and analyse the decision to withhold or withdraw life-sustaining treatment (LST) in a population of very old patients admitted to the ICU.METHODS: This prospective study included intensive care patients aged ≥ 80 years in 309 ICUs from 21 European countries with 30-day mortality follow-up.RESULTS: LST limitation was identified in 1356/5021 (27.2%) of patients: 15% had a withho
Reptiles use pterin and carotenoid pigments to produce yellow, orange, and red colors. These conspicuous colors serve a diversity of signaling functions, but their molecular basis remains unresolved. Here, we show that the genomes of sympatric color morphs of the European common wall lizard (Podarcis muralis), which differ in orange and yellow pigmentation and in their ecology and behavior, are vi
The fission process still remains a main factor that determines the stability of the atomic nucleus of heaviest elements. Fission half-lives vary over a wide range, 10^−19 to 10^24 s. Present experimental techniques for the synthesis of the superheavy elements that usually measure α-decay chains are sensitive only in a limited range of half-lives, often 10^5 to 10^3 s. In the past years, measureme
Background: The ESPAC-3 trial showed that adjuvant gemcitabine is the standard of care based on similar survival to and less toxicity than adjuvant 5-fluorouracil/folinic acid in patients with resected pancreatic cancer. Other clinical trials have shown better survival and tumour response with gemcitabine and capecitabine than with gemcitabine alone in advanced or metastatic pancreatic cancer. We
We analysed 68 candidate planetary systems first identified during Campaigns 5 and 6 (C5 and C6) of the NASA K2 mission. We set out to validate these systems by using a suite of follow-up observations, including adaptive optics, speckle imaging, and reconnaissance spectroscopy. The overlap between C5 with C16 and C18, and C6 with C17, yields light curves with long baselines that allow us to measur
