Sökresultat

This package facilitates working with probability distributions by means of Monte-Carlo methods, in a way that allows for propagation of probability distributions through functions. This is useful for, e.g., nonlinear uncertainty propagation. A variable or parameter might be associated with uncertainty if it is measured or otherwise estimated from data. We provide two core types to represent proba

The possible benefits of introducing central counterparties, or clearing houses, in the credit derivatives market is currently intensively debated among bankers and policymakers. The exact outcome of this discussion is not yet clear but regardless of how any eventual clearing is organized the actual clearing house needs to be properly capitalized and needs to maintain accurate margin (collateral)

When testing for means there are two classical assumptions to be considered, normality and equal variances (equal covariance matrices). Historically more attention seems to be directed towards violation of the assumption of equal variances, which is referred to as the Behrens-Fisher problem, than the assumption of normality. Our attention is equally directed to both the issues. We propose a bootst

BACKGROUND: Normal cell division is coordinated by a bipolar mitotic spindle, ensuring symmetrical segregation of chromosomes. Cancer cells, however, occasionally divide into three or more directions. Such multipolar mitoses have been proposed to generate genetic diversity and thereby contribute to clonal evolution. However, this notion has been little validated experimentally. PRINCIPAL FINDINGS:

We propose simple estimation of the location parameter for a density that is unbounded at the mode. The estimator maximizes a modified likelihood in which the singular term in the full likelihood is left out, whenever the parameter value approaches a neighborhood of the singularity location. The consistency and super-efficiency of this maximum leave-one-out likelihood estimator is shown through a

Syftet med föreliggande studie är att presentera en energi- och miljösystemanalys för en specifik biogasanläggning samt att beskriva och kostnadsberäkna åtgärder för att optimera systemet. En övergripande målsättning är också att studien ska kunna fungera som modell för kommande energi- och miljösystemstudier av andra specifika biogasanläggningar. Analysen innefattar direkta effekter som energian

1. State space models are starting to replace more simple time series models in analyses of temporal dynamics of populations that are not perfectly censused. By simultaneously modelling both the dynamics and the observations, consistent estimates of population dynamical parameters may be obtained. For many data sets, the distribution of observation errors is unknown and error models typically chos

En av behandlingsmetoderna mot tumörer i levern på Lunds Universitetssjukhus är SIRT som står för ”Selective Internal RadioTherapy” det vill säga en intern radioterapeutisk behandling, i detta fall specifikt för levern. Behandlingen är cirka tio år gammal och i Lund har den utförts sedan december 2010. Under våren 2012 behandlades tre patienter med SIRT då de inte kan få sina cancertumörer i leverIntroduction: Cancer treatment is a process with continuous development. The most common treatment, within the field of radiation physics, is external radiation therapy, whereas one of the least common methods is Selective Internal RadioTherapy (SIRT). SIRT is a rather novel method for treating liver carcinoma. Microspheres containing 90Y are infused directly into the liver, via the hepatic artery

Alzheimer's disease (AD) and frontotemporal dementia (FTD) are characterized by progressive neuronal loss and microvacuolization, although with different distributions of cortical involvement. In contrast to AD there is no amyloid, senile plaques or tangles in FTD. The involvement of chromosome 19 in AD has been associated with apoliprotein E (ApoE) and the epsi4 gene frequency has been related to

Finger tapping to isochronous pacing stimuli is a well established experimental paradigm first described in the late 19th century. Two variables of common interest in rhythmic tapping tasks are timing variability and constant error. However, a difficulty when estimating these variables is that at interstimulus intervals longer than 2 seconds participants regularly overshoot the target interval and

Falsterbo Peninsula on the south coast of Sweden is low-lying and exposed to flooding. In 1872 the extremestorm surge Backafloden caused large devastation on the Swedish, Danish, and German coasts in the SouthBaltic Sea. For the Falsterbo Peninsula, the peak storm surge level is estimated to have been 240 cm abovenormal. If a similar event happened today, the consequences would be far worse, as exFalsterbo Peninsula on the south coast of Sweden is low-lying and exposed to flooding. In 1872 the extreme storm surge Backafloden caused large devastation on the Swedish, Danish, and German coasts in the South Baltic Sea. For the Falsterbo Peninsula, the peak storm surge level is estimated to have been 240 cm above normal. If a similar event happened today, the consequences would be far worse, as

The normal-like molecular subtype of breast cancer has not been well characterized and is currently not included in the clinically approved PAM50 molecular subtype classification. Tumors classified as normallike display high expression of basal epithelial genes and low expression of luminal epithelial genes, but also high expression of genes expressed by non-epithelial cell types including adipocy

The stochastic Lagrange wave model is a realistic alternative to the Gaussian linear wave model, which has been successfully used in ocean engineering for more than half a century. This paper presents exact slope distributions and other characteristic distributions at level crossings for symmetric and asymmetric Lagrange space and time waves. These distributions are given as expectations in

Methods currently used for inventory control in industry are with few exceptions developed more than forty years ago. This is for instance the case with methods like reorder point sys-tems, cover-time planning and material requirements planning (MRP). Lead times at that time were typically several weeks and months and order quantities covered typically de-mand over several months. Since then both

We present new in-situ measurements of particle rotations and energy dissipation during compression of 3D packings of stiff, frictional particles. Two confined, uniaxial compression tests with different degrees of lateral confinement are discussed. X-ray computed tomography and 3D X-ray diffraction were combined to provide inter-particle forces, slip and roll distances, twist angles, and energy di