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Markers of Prognosis in Neurodegenerative Dementia

Popular Abstract in Swedish De två vanligaste typerna av neurodegenerativ demenssjukdom är Alzheimer’s sjukdom och Lewy body demens. Båda sjukdomarna drabbar framförallt äldre människor och risken att insjukna ökar med stigande ålder. Detta innebär att demenssjukdom kommer att bli vanligare i samhället, eftersom vi blir allt äldre och andelen invånare >65 år blir allt större. Att drabbas av demensBackground: A prognostic marker should provide information about course and outcome of disease, e.g. predict time to a given endpoint or rate of progression due to disease in patients or subgroups of patients. Prognostic markers could be targeted to apply during the entire clinical course or just during distinct stages of the disease. Aim: The aim of this thesis is to identify, review and qualif

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"Arca lui Noe" ("Noah’s Ark", 1944) is based on a folk tale influenced by Bogomilism. Brother and Unbrother stand for the antinomic duality of the absolute principle. Fellow and Unfellow are indestructibly united. Unbrother cannot be mastered and Brother would be an ontic sterility if his fellow absent. However the Bogomilic vision becomes complicated in Blaga's meaning. The greybeard Brother, the

Effect of Temperature Stratification on the Auto-Ignition of Lean Ethanol/Air Mixture in HCCI Engine

It has been known from multi-zone simulations that HCCI combustion can be significantly affected by temperature stratification of the in-cylinder gas. With the same combustion timing (i.e., crank angles at 50% heat release, denoted as CA50), large temperature stratification tends to prolong the combustion duration and lower down the in-cylinder pressure-rise-rate. With low pressure-rise-rate HCCI

Depolarization Changes During Acute Myocardial Ischemia by Evaluation of QRS Slopes: Standard Lead and Vectorial Approach

Diagnosis and risk stratification of patients with acute coronary syndromes can be improved by adding information from the depolarization phase (QRS complex) to the conventionally used ST-T segment changes. In this study, ischemia-induced changes in the main three slopes of the QRS complex, upward (I-US) and downward (I-DS) slopes of the R wave as well as the upward (I-TS) slope of the terminal S

Intimate partner violence against women in rural Vietnam - different socio-demographic factors are associated with different forms of violence: Need for new intervention guidelines?

Background: This population-based study investigated the different forms, magnitude and risk factors of men's violence against women in intimate relationships in a rural part of northern Vietnam and whether a difference in risk factors were at hand for the different forms of violence. Vietnam has undergone a rapid transition in the last 20 years, moving towards a more equal situation for men and w

Vascular and lung function related to ultrafine and fine particles exposure assessed by personal and indoor monitoring: a cross-sectional study

Background: Exposure to ambient air particulate matter (PM) has been linked to decline in pulmonary function and cardiovascular events possibly through inflammation. Little is known about individual exposure to ultrafine particles (UFP) inside and outside modern homes and associated health-related effects. Methods: Associations between vascular and lung function, inflammation markers and exposure

Defining strong ownership: Institutional Determinants and Stakeholder Interests in Vietnamese Development Planning

The current development debate emphasizes national ownership of the development agenda as a precondition for sustainable development and aid effectiveness. Vietnam is often held up as a good example of strong ownership. Yet, the ownership concept is not clearly defined or understood due to a lack of empirically rooted evidence and analysis. This study examines the key elements of development owne

The Gaia-ESO Survey: the first abundance determination of the pre-main-sequence cluster gamma Velorum

Context. Knowledge of the abundance distribution of star forming regions and young clusters is critical to investigate a variety of issues, from triggered star formation and chemical enrichment by nearby supernova explosions to the ability to form planetary systems. In spite of this, detailed abundance studies are currently available for relatively few regions. Aims. In this context, we present th

Children with Type 1 diabetes The initial education process and the impact on children and their parents over the first two years

The overall aim of this thesis was to investigate the initial diabetes education process, the impact on children and their parents and parental satisfaction with the care received one and two years subsequent to the child’s diagnosis. In order to seek a deeper understanding for how the diabetes team’s initial education process works from admission to discharge among families with a child newly dia

Impact of the ion-ion energy transfer on quantum computing schemes in rare-earth doped solids

We analyze the Ce3+-Pr3+:Y2SiO5 emission spectra obtained under selective excitation of the two Ce3+ sites in Y2SiO5 and we show clear evidence of direct energy transfer from Ce3+ to Pr3+. Energy transfer microparameters were calculated from the experimental spectral overlap between the Ce3+ emission and the Pr3+ and Eu3+ absorptions from which, the transfer mechanisms Ce3+-> Pr3+ are concluded to

Fortunas klädnader : lycka, olycka och risk i det tidigmoderna Sverige

Fortuna’s Guises: Fortune, Misfortune, and Risk in Early Modern Sweden. This dissertation explores learned conceptions of uncertainty and risk during the period stretching approximately between 1560 and 1720. Previous historical overviews of the ideas about risk hold that pre-industrial societies viewed all worldly happenings as emanations of God’s will or other forces lying beyond human control.

Psychometric properties of the Chinese version of the Functional Assessment of Cancer Therapy-Cervix (FACT-Cx) measuring health-related quality of life

Background: The Functional Assessment of Cancer Therapy (FACT) is one of the most commonly used self-report instruments for evaluation of health-related quality of life in oncology patients. However, cultural considerations necessitate testing of the subscales in different populations. We sought to qualitatively and quantitatively investigate the applicability and psychometric properties of the Ch

Hydrogen analysis by p-p scattering in geological material

It has been concluded by geologists that a significant amount of hydrogen is stored as point defects in nominally anhydrous minerals. Determination of the amount of hydrogen bound in these minerals is a step towards determining the total water content of the earth mantle as well as comprehending its internal water cycle. The possibility to measure hydrogen in thin geological samples by elastic p-p

Carriage of penicillin-resistant Streptococcus pneumoniae by children in day-care centers during an intervention program in Malmo, Sweden

BACKGROUND: An increasing incidence of penicillin-resistant Streptococcus pneumoniae (PRP) was detected in Malmo in 1994. OBJECTIVE: To evaluate clonality and factors facilitating the spread of PRP among children in day-care centers (DCCs). METHODS: We used phenotypic and DNA-fingerprinting methods in conjunction with epidemiologic data from the South Swedish Pneumococcal Intervention Project's in

Purification and properties of the cGMP-inhibited cAMP phosphodiesterase from bovine aortic smooth muscle

Pure cGMP-inhibited cAMP phosphodiesterase (cGI-PDE) in micrograms quantities was isolated from bovine aortic smooth muscle after more than 5000-fold purification using DEAE ion-exchange and affinity chromatography with a derivative of the specific cGI-PDE inhibitor cilostamide conjugated as a ligand to aminoethyl agarose (CIT-agarose). The cGI-PDE, which constituted about half of the high affinit

Proton-Induced X-Ray Emission Analysis - A New Tool in Quantitative Dermatology

Proton-Induced X-ray emission analysis (PIXE) constitutes a method for trace element analysis characterized by multielemental capability, detection limits in the low ppm-range and size resolution down towards a micrometre. In applications where the sensitivity of the Electron-Induced X-ray Emission (EIXE) analysis is not sufficient and where a spatial resolution not better than a few micrometres i

Trace gas exchange in a high-arctic valley 1. Variations in CO2 and CH4 flux between tundra vegetation types

Ecosystem exchanges of CO2 and CH4 were studied by chamber techniques in five different vegetation types in a high arctic valley at Zackenberg, NE Greenland. The vegetation types were categorized as Cassiope heath, hummocky fen, continuous fen, grass land and Salix arctica snowbed. Integrated daytime fluxes for the different vegetation types of the valley showed that the fen areas and the grasslan

Investigation of Performance and Emission Characteristics of a Heavy Duty Natural Gas Engine Operated with Pre-Chamber Spark Plug and Dilution with Excess Air and EGR

This article deals with application of turbulent jet ignition technique to heavy duty multi-cylinder natural gas engine for mobile application. Pre-chamber spark plugs are identified as a promising means of achieving turbulent jet ignition as they require minimal engine modification with respect to component packaging in cylinder head and the ignition system. Detailed experiments were performed wi

Effects of work ability and health promoting interventions for women with musculoskeletal symptoms: A 9-month prospective study

Background: Women working in the public human service sector in 'overstrained' situations run the risk of musculoskeletal symptoms and long-term sick leave. In order to maintain the level of health and work ability and strengthen the potential resources for health, it is important that employees gain greater control over decisions and actions affecting their health - a process associated with the