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Introduction Using body mass index (BMI) as a proxy, previous Mendelian randomization (MR) studies found total causal effects of general obesity on polycystic ovarian syndrome (PCOS). Hitherto, total and direct causal effects of general- and central obesity on PCOS have not been comprehensively analyzed. Objectives To investigate the causality of central- and general obesity on PCOS using surrogat
Colour vision allows animals to use the information contained in the spectrum of light to control important behavioural decisions such as selection of habitats, food or mates. Among arthropods, the largest animal phylum, we find completely colour-blind species as well as species with up to 40 different opsin genes or more than 10 spectral types of photoreceptors, we find a large diversity of optic
This paper constructs the first long-run estimates of Irish regional GDP over the twentieth century and traces the relative economic performance of Ireland’s regions since independence. Using an array of data sources available at a county level, output in Agriculture, Industry and Services in benchmark census years is estimated. Applying a variety of alternative measures, we find a reduction in re
This study explores how listeners use verb constructions to describe everyday sounds. It considers (i) how the verb constructions provide Gestalt to events in the form of activities, processes and states, and (ii) how the constructions correspond to different aspects of a soundscape (sound sources, acoustic properties, and listener reactions). We found that verb constructions primarily describe so
This study investigates the practical integration of Building Information Modelling (BIM) and Building Energy Modelling (BEM) for energy-efficient building design. This research explores the challenges and opportunities of openBIM-to-BEM workflows by drawing on a literature review and a real-world case study in Östergötland County, typical of the Million Programme, a large public housing initiativ
Scholte wave surveys were conducted at both the laboratory and field scales to evaluate the reliability of distributed acoustic sensing (DAS) with a fiber-optic cable resting on top of unconsolidated sedimentary deposits to determine the distribution of S-wave velocity underneath. Laboratory measurements performed in a controlled environment at the Deltares Laboratory facility demonstrated that DA
Tilt table testing (TTT) has been used for decades to study short-term blood pressure (BP) and heart rate regulation during orthostatic challenges. TTT provokes vasovagal reflex in many syncope patients as a background of widespread use. Despite the availability of evidence-based practice syncope guidelines, proper application and interpretation of TTT in the day-to-day care of syncope patients re
Objective: North Sea Progressive Myoclonus Epilepsy (NS-PME) is a rare genetic disorder characterized by ataxia, myoclonus and seizures with a progressive course. Although the cause of NS-PME is known, namely a homozygous mutation in the GOSR2 gene (c.430 G>T; p. Gly144Trp), sufficient treatment is lacking. Despite combinations of on average 3–5 anti-seizure medications (ASMs), debilitating myoclo
Cadmium telluride (CdTe) solar cell technology is a promising candidate to help boost green energy production. However, impurities and structural defects are major barriers to improving the solar power conversion efficiency. Grain boundaries often act as aggregation sites for impurities, resulting in strain localization in areas of high diffusion. In this study, we demonstrate the use of scanning
Geopolitical, health and economic events have led to an accumulated surge in energy prices in the UK at the beginning of the 2020s. In response, studies and media reports show that households have had to reduce the running of their heating systems to cut their energy bills. However, there is limited research on the impact of this context on indoor thermal conditions and occupants’ ability to meet
This chapter analyses trajectories of contextual reconstruction of machine learning models with calibrated weights, sometimes known as pre-trained or foundation models, as they are made operational in specific settings. Through ethnographic vignettes on car detection, bird tracking, and medical technology, it underscores the importance of cooperation and negotiation among actors facing contingenci
With current interest from the heavy-duty industry in high-octane renewable fuels like methanol, the currently used compression ignition engines will have to be adapted to dual-fuel (DF) type combustion systems or replaced by spark-ignition (SI) engines. Since both DF and SI engines are characterized by a premixed air–fuel mixture, there is a risk that part of the unburned mixture auto-ignites bef
Industrial symbiosis, a concept derived from industrial ecology, emphasizes the collaborative and synergic production among industries. The particular focus is on cyclical flows of resources (material, energy, water, and/or by-products), in order to minimize impacts on the environment. In this way, an industry could reuse the discarded resources of another industry as an input to production. Essen
Field bio-remediation techniques (FBRT) can be a low cost method to avoid the removal of top layers of soil which are rich in organic matter and bio diversity. The use of native microorganisms in FBRT is preferable because non-indigenous species can transfer their genetic material to the environment with negative impacts on the local ecological equilibrium. Petroleum Produced Water (PPW) is an imp
In recent years, the development of meat-and dairy analogues has increased to meet demands from consumers, as well as serving as environmentally beneficial alternatives to meat and dairy. While traditional plant-based diets based on whole-foods have been shown to lead to beneficial health effects, the new analogues differ vastly from the ingredients of a whole foods, plant-based diet and the effec
The date is October 8th, 2022 in Herzogenaurach, Germany. You are a board member of Adidas, a world renowned sportswear brand - a brand which has seen an immense growth over the past decade, growth which has also translated into a record valuation for the company in the stock market. But today is not a day which calls for celebration. One of your key collaborators, a person which you could attribu
I denna uppsats har jag fortsatt den ndersökning av svenska inlärare av franska som påbörjades i min C-uppsats. Avsikten har varit att studera om de språkliga avvikelser från den franska normen som upptäcktes i den förra studien kvarstår även denna gång då studien inte längre gäller vokaldurationer utan istället det tonala förloppet och final förlängning. Svenska inlärares prosodiska konstruktion
Denna uppsats har till syfte att undersöka huruvida det, med hjälp av teknisk analys, föreligger större möjlighet att skapa lönsamma handelsstrategier för index än för enskilda aktier. Vi kommer även att belysa hur god avkastning sådana strategier kan generera i förhållande till en jämförelsestrategi där man köper och håller tillgången under hela perioden. Handelsstrategier baserade på dubbla löpa
