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Non-typeable Haemophilus influenzae (NTHi) is a common pathogen associated with diseases such as acute otitis media or exacerbations in patients with chronic obstructive pulmonary disease. The biofilm-forming capability substantially contributes to the persistence of NTHi. However, the regulation of biofilm formation is not completely understood. Quorum sensing regulated by autoinducer-2 produced

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Life expectancy for patients with haemophilia (PWH) has significantly increased in the last decades, due to improvement of clotting factor replacement therapy. However, despite a lower cardiovascular mortality rate and contrasting prevalence for non-fatal ischaemic heart disease (IHD), cardiovascular diseases are increasing in PWH. The prevalence of cardiovascular risk factors in PWH is as prevale

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We discuss the preimaginal development of the mosquito Aedes aegypti from the point of view of the statistics of developmental times and the final body-size of the pupae and adults. We begin the discussion studying existing models in relation to published data for the mosquito. The data suggest a developmental process that is described by exponentially distributed random times. The existing data s

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Motivated by the well established idea that collective wisdom is greater than that of an individual, we propose a novel learning dynamics as a sort of companion to the Abelson model of opinion dynamics. Agents are assumed to make independent guesses about the true state of the world after which they engage in opinion exchange leading to consensus. We investigate the problem of finding the optimal

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Molecular oxygen activation at single transition metal atom sites is critical for catalysis but remains challenging to control. Here we investigate a manganese–cobalt bi-metallic coordination network on graphene, where Co(i) atoms are tetracoordinated by nitrogen. Combining density functional theory with in situ infrared-visible sum-frequency generation and ambient-pressure X-ray photoelectron spe

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Climate change and increasing urbanization gives societies great challenges in managing urban planning for a sustainable future. Urbanization aggravates floods by increasing the amount of impermeable surfaces and by modifying flow routes. Resilience is the capability to recover from a stress and high resilience is seen as the goal of a healthy development. By including the concept of resilience in

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BACKGROUND: Radiostereometric analysis (RSA) is a highly accurate tool to detect implant migration and predict loosening following total knee arthroplasty (TKA). However, little is known about the predisposing risk factors for implant migration, nor which migration profile should be considered physiological (i.e., merely part of an implant-settling phase) and which should be considered pathologica

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PURPOSE OF REVIEW: Malnutrition is frequent in patients with acute kidney injury. Nutrient clearance during renal replacement therapy (RRT) potentially contributes to this complication. Although losses of amino acid, trace elements and vitamins have been described, there is no clear guidance regarding the role of micronutrient supplementation. RECENT FINDINGS: A scoping review was conducted with t

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Syftet med denna masteruppsats är att undersöka människors upplevelser av att delta i flyktingmottagandet i Malmö under hösten 2015. Uppsatsen studerar motiveringar till varför volontärer beslutat sig för att hjälpa. Dessa analyseras främst genom Marcel Mauss teori om gåvosystem: volontärarbete, eller att hjälpa, ses som en gåva i uppsatsen. Motiveringarna analyseras också genom Erving Goffmans drThe purpose of this master’s thesis is to explore the experience of people who helped in the refugee reception in the city of Malmö, Sweden, in the fall of 2015. The thesis delves into the reasons and motivations to why volunteers decided to help. These are primarily analysed through Marcel Mauss’ gift-exchange theory where volunteering is seen as a gift; and secondarily by Erving Goffman’s dramat

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According to the values of democracy, the governors should be held accountable for their actions and omissions by the governed. However, on a global level there is a deep deficit of democratic accountability. The Inter-Parliamentary Union, (IPU) whose members consist of almost all of the national parliaments in the world, claims to increase accountability within the UN system. This thesis uses the

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This study aims to identify important market characteristics that affect international market establishments in the IT consulting industry. A qualitative case study has been conducted at an IT consulting firm, where Osterwalder's Business Model Canvas has been used as a tool to identify and compare market characteristics to existing theory regarding internationalisation in the Knowledge-Intens

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Vi vill karaktärisera fenomenet konceptbutik och undersöka hur den kan fungera som ett verktyg, för att bygga upp sitt varumärke. Konceptbutiker handlar om att ge upplevelser och erbjuda aktiviteter. Genom de fem sinnena kan man involvera kunden och ge den en upplevelse. Det optimala för en konceptbutik är att enbart sälja ett varumärke då dess syfte är att stärka det. Personalen och interiören ha

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BACKGROUND: Allergic contact dermatitis (ACD) from protective gloves is often caused by rubber additives, such as accelerators. However, while accelerator-free rubber gloves are available, they still cause ACD in some individuals.OBJECTIVES: A new allergen, 2-cyаnоethyl dimethyldithiocarbamate, (CEDMC), has recently been identified in accelerator-free gloves, and we here provide a first in vitro c

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The MYCN proto-oncogene is frequently amplified in a subgroup of highly aggressive neuroblastomas. The molecular mechanism(s) by which the overexpressed MYCN contributes to an aggressive tumor cell behavior is not well understood. Recently, it was reported that the ID2 gene is a direct target for the MYCN and MYC transcription factors, and that ID2 expression and MYCN amplification correlate posit

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Sympathetic neuronal differentiation is associated with favorable prognosis of neuroblastoma (NB), the most common extra-cranial solid tumor of early childhood. Differentiation agents have proved useful in clinical protocols of NB treatment, but using them as a sole treatment is not sufficient to induce tumor elimination in patients. Therefore, complementary approaches, such as immunotherapy, are