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Lactobacillus reuteri metabolises glycerol efficiently to form 3-hydroxypropionic acid (3-HP) and 1,3-propanediol (1,3PDO) by the same mechanism as that for 1,2-propanediol (1,2PDO) conversion to propionic acid and propanol via its propanediol utilization (pdu) pathway. Pdu enzymes are encoded by the pdu-operon, which also contain genes encoding the shell proteins of the microcompartment housing t

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Purpose: To investigate the outcome following adjuvant doxorubicin and ifosfamide in a prospective non-randomised study based on a soft tissue sarcoma (STS) patient subgroup defined by specific morphological characteristics previously shown to be at a high-risk of metastatic relapse. The expected 5-year cumulative incidence of metastases in patients with this risk profile has previously been repor

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We evaluated the performance of the Disease State Index (DSI) method when predicting progression to Alzheimer's disease (AD) in patients with subjective cognitive impairment (SCI), amnestic or non-amnestic mild cognitive impairment (aMCI, naMCI). The DSI model measures patients' similarity to diagnosed cases based on available data, such as cognitive tests, the APOE genotype, CSF biomarkers and MR

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Early-life inorganic arsenic exposure influences not only child health and development but also health in later life. The adverse effects of arsenic may be mediated by epigenetic mechanisms, as there are indications that arsenic causes altered DNA methylation of cancer-related genes. The objective was to assess effects of arsenic on genome-wide DNA methylation in newborns. We studied 127 mothers a

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Objectives: The paper describes recruitment results and characteristics of the UP-TECH clinical trial sample, including level of care services use, informal caregiver burden and its determinants.Methods: UP-TECH is designed to test innovative care solutions for community-dwelling patients with moderate stage Alzheimer's disease and their caregivers in Italy. Four hundred and fifty patient-caregive

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One of the conclusions from comparative empirical studies of the structural challenges towards making global production and consumption patterns compatible with environmental limits is that rich countries would need to ‘degrow’ (O’Neill 2015; Fritz and Koch 2016). To shed light on the potential role of the state in such a planned downscaling process the paper compares state roles in a capitalist e

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This paper presents results from a project on the experiences of Palestinian refugee youth in Lebanon, taking part in NGO programs for facilitating university education. To what extent may such informal educational projects be instrumental in circumventing and counteracting social exclusion? And how do such initiatives interrelate with constructions of senses of “Palestinianess” among their young

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Metal nanoparticles (NPs), in particular gold NPs, are often used in the fabrication process of semiconductor nanowires. Besides being able to induce the 1D crystallization of new material, it is highly beneficial if the NPs can be used to dictate the position and diameter of the final nanowire structure. To achieve well-defined NP arrays of varying diameter and pitch distances for nanowire growth

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Inhibition of mitochondrial permeability transition (mPT) has emerged as a promising approach for neuroprotection and development of well-tolerated mPT inhibitors with favorable blood-brain barrier penetration is highly warranted. In a recent study, 28 clinically available drugs with a common heterocyclic structure were identified as mPT inhibitors e.g. trifluoperazine, promethazine and nortriptyl

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The Symphony study showed that at 1 year posttransplant, a regimen based on daclizumab induction, 2 g mycophenolate mofetil (MMF), low-dose tacrolimus and steroids resulted in better renal function and lower acute rejection and graft loss rates compared with three other regimens: two with low-doses of cyclosporine or sirolimus instead of tacrolimus and one with no induction and standard cyclospori

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The quantum theory of measurement has been with us since quantum mechanics (QM) was invented. It has recently been invigorated, partly due to the increasing interest in quantum information science. In this, partly pedagogical review, I attempt to give a self-contained overview of the basis of (non-relativistic) QM measurement theory expressed in density matrix formalism. I will not dwell on the ap

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The frame story
takes place in a dystopian Europe, possibly some kind of European Union around 2050 – in a state of conflicts and decay. The protagonists are a retired general, Piscator (cf. Fisher King) and a former journalist, Perle Vaus (cf. Perlesvaus/Perceval/Parsifal). She lost her home because of a new genderrelated law and stays homeless with others, covered by the Saxon bridge.

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The main aim of this thesis is to analyze the process of institutionalization and neo-/interdisciplinarization in Women’s/Gender/Feminist Studies (WGFS) in Sweden, and the construction of feminist knowledge within this process. Furthermore, the thesis aims to contribute to the feminist debates on academic feminism as a transformative project. Three questions have guided the research process: 1) Ho

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Context: It is an enigma that agile projects can succeed ‘without requirements’ when weak requirements engineering is a known cause for project failures. While agile development projects often manage well without extensive requirements test cases are commonly viewed as requirements and detailed requirements are documented as test cases.Objective: We have investigated this agile practice of using t

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The erection of roadside memorials in Sweden is commonly considered a novel practice, appearing during the last 10-15 years. Nevertheless similar precedent practices can be found in the history of Sweden. Stories about marking the site of an unexpected death with a cross could be said to date back to the eleventh century legend of Saint Sigfrid, telling of the first English missionary to spread C

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The drafters of the 1990 Dublin Convention knowingly and willfully disregarded divergences among Member States' protection systems. Like a boomerang, the fallacy of this approach has now reappeared in cases where asylum seekers have challenged transfers under the Convention, tasking judges to tackle a problem which its drafters avoided. The core issue of this article is whether and when such diver

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Denna uppsats undersöker hur det svenska genomförandet av de nya gränsförfarandena, som del av EU:s nya migrations- och asylpakt, kan påverka asylsökandes rätt till frihet under artikel 5 i Europakonventionen. Fokus ligger på screeningförfarandet, asylgränsförfarandet och gränsförfarandet för återvändande, vilka tillsammans skapar en ny inresefas vid ankomst till Unionen. Pakten bygger på den rättThis thesis examines how the Swedish implementation of the new border procedures, as part of the new EU Pact on Migration and Asylum, may affect asylum seekers’ right to liberty under Article 5 of the European Convention on Human Rights. The focus is on the screening procedure, the asylum border procedure and the return border procedure, which together create a new pre-entry phase when arriving to

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From the mid-2000s onwards, deep and comprehensive bilateral ‘new generation’ free trade agreements (NGFTAs) became the central instrument of the European Union’s (EU) Common Commercial Policy (CCP). The Comprehensive Economic and Trade Agreement (CETA) between the EU and Canada was initially praised for its innovative scope and design and intended to serve as an archetype for future EU trade agre