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Atrial Fibrillation in Long QT Syndrome by Genotype

BACKGROUND: Long QT syndrome (LQTS) is caused by the abnormal function of ion channels, which may also affect atrial electrophysiology and be associated with the risk of atrial fibrillation (AF). However, large-scale studies of AF risk among patients with LQTS and its relation to LQTS manifestations are lacking. We aimed to assess the risk of AF and its relationship to the LQTS genotype and the lo

HLA Class I Genotype Is Associated with Relapse Risk after Allogeneic Stem Cell Transplantation for NPM1-Mutated Acute Myeloid Leukemia

Mutation-bearing peptide ligands from mutated nucleophosmin-1 (NPM1) protein have been empirically found to be presented by HLA class I in acute myeloid leukemia (AML). We hypothesized that HLA genotype may impact allogeneic hematopoietic stem cell transplantation (allo-HCT) outcomes in NPM1-mutated AML owing to differences in antigen presentation. We evaluated the effect of the variable of predic

Towards a unified protocol for handling of CSF before β-amyloid measurements

Background: Widespread implementation of Alzheimer's disease biomarkers in routine clinical practice requires the establishment of standard operating procedures for pre-analytical handling of cerebrospinal fluid (CSF). Methods: Here, CSF collection and storage protocols were optimized for measurements of β-amyloid (Aβ). We investigated the effects of (1) storage temperature, (2) storage time, (3)

Reliability of virtual non-contrast computed tomography angiography: comparing it with the real deal

Background:Computed tomographic angiography (CTA) may require a non-contrast enhanced dataset for the diagnostic workup. By using dual-energy acquisition, it is possible to obtain a virtual non-contrast-enhanced (VNC) dataset, thereby possibly eliminating the non-contrast acquisition and reducing the radiation dose.Purpose:To compare image quality of VNC images reconstructed from arterial phase du

Scaling up nature-based solutions for climate-change adaptation : Potential and benefits in three European cities

Many exemplary projects have demonstrated that Nature-based Solutions (NBS) can contribute to climate change adaptation, but now the challenge is to scale up their use. Setting realistic policy goals requires knowing the amount of different NBS types that can fit in the urban space and the benefits that can be expected. This research aims to assess the potential for a full-scale implementation of

Resource Management in Distributed Camera Systems

The aim of this work is to investigate different methods to solve the problem of allocating the correct amount of resources (network bandwidth and storage space) to video camera systems. Here we explore the intersection between two research areas: automatic control and game theory. Camera systems are a good example of the emergence of the Internet of Things (IoT) and its impact on our daily lives

The political economy of degrowth

What is degrowth and what are its implications for political economy? Divided in three parts, this dissertation explores the why, what, and how of degrowth.The first part (Of growth and limits) studies the nature, causes, and consequences of economic growth. Chapter 1: Understanding economic growth answers a series of questions about the nature of economic growth: What is it exactly that grows? By

Decentraliserad förvaltning av EG:s finanser

När EU:s budget är antagen ligger det övergripande ansvaret på kommissionen att se till att den genomförs i överensstämmelse med principen om god ekonomisk förvaltning. Eftersom gemenskapen inte förfogar över egen tull- och skattemyndighet och för övrigt inte har möjligheter eller resurser att administrera och förvalta den övervägande delen av budgeten sker det genom medlemsstaternas nationella or

Carrier Delay in Multimodal Transport

This research is a critical analysis of a delay regime for multimodal transport, or door-to-door transport. At this day, there are no mandatory rules governing multimodal transport, but a process of creating a set of rules are pending both within UNCITRAL as well as the European Union. Due to the increased use of containers in shipping, multimodal transport has become more common. For this purpose

It’s a Man’s Weed : Mainstream Online News and Visibility During America’s New Marijuana Legalization Era

The aim of this thesis is to shed some light on the emerging mainstream news discourses connected to marijuana’s legalization in parts of the United States by asking who is most involved in these discourses, what connections involvement may have to social status and social factors, most significantly gender, as well as what a few discursive themes in marijuana-related coverage might be, and what f

Education for All - Including Undocumented Children?

Education for all, what does it mean? For me, that all children have the right to education and are given possibilities to obtain this right. Though, is that the reality for all children in practice? Several reports, national as well as international, indicate that this is not the case for undocumented children in Sweden, despite their right to actual enjoyment of the rights protected in the Conve

Skönlitteratur och läsning som forskningsfråga inom B&I : en metateoretisk analys av 21 masteruppsatser

This master’s thesis examines 21 master’s theses written in Library and Information Science in Sweden between the years 2010 and 2013. The master’s theses are written in Lund, Borås and Uppsala and all of them have literature and/or reading as subject matters. The aim of the thesis is to investigate how master’s theses in our time handle the question of reading and literature as a subject matter i

Att uppnå beviskravet i mål om flyktingstatus - Frågor om juridisk sannolikhet och matematisk sannolikhet i en juridisk kontext

Detta arbete behandlar frågan om vad det inom migrationsrätten gällande beviskravet sannolikt innebär ur ett sannolikhetsteoretiskt perspektiv vid tillämpning framför allt av utlänningslagen (2005:716) 4 kap. 1 §. Utvald del av denna paragraf tolkas och delas upp i delteman. Utifrån dessa delteman undersöks vad som måste uppnå vilken sannolikhet och hur sannolikheten för olika delteman påverkar saThis is a thesis on the issue of what the evidentiary requirement within the field of migration law, probable, implies, from a probabilistic point of view, especially when applying the 1st article of the 4th chapter in the Swedish Aliens Act (2005:716), about refugee status. A selected part of this article is interpreted and divided into sub-themes of proof (these could also be referred to as prop

Reading the Diaspora

This thesis set the goal to contribute to the fields of diaspora studies and cultural studies from a media and communication studies angle by addressing the blank spots ‘white minorities’ and book use. White diasporas are nearly invisible within academia and very often ‘under the radar’ in society as well. Books are underresearched within media studies in favour of other media. On the other hand,

Silence is Golden : a Critical Discourse Analysis of the Representation of Billionaires and Economic Inequality in the Swedish News Media

Economic inequality is growing rapidly worldwide. Despite research showing that higher inequality within a society corresponds with a higher rate of public health and social problems, there exist little organized resistance against the neo-liberal economic policies that allow the super-rich to pull away from the rest of the population. Even though the causes of poverty cannot be separated from the

Direktupphandling vid synnerlig brådska – är det flexibla förfarandet rättssäkert?

Offentlig upphandling handlar om hur den offentliga sektorn ska agera vid inköp och har därmed en betydande påverkan på samhällsekonomin. Essentiella samhällsfunktioner som exempelvis sjukvård och skolor tillgodoses genom offentlig upphandling. Eftersom inköpen görs via skattemedel har samhällsmedborgare ett intresse av att förfarandet går rätt till. Vidare har leverantörer ett intresse av att förPublic procurement concerns how the public sector should act when making purchases and therefore has a great impact on the national economy. Fundamental societal functions such as healthcare and education are supported through public procurement. Because these purchases are made using tax revenue, citizens have an interest in ensuring that the procedure is conducted properly. Moreover, suppliers h

Klimatberäkning i små- och medelstora företag

Bygg- och fastighetssektorn stod år 2020 för 21% av Sveriges totala utsläpp av växthusgaser (Boverket, 2023a). För att synliggöra och därigenom minska klimatpåverkan vid uppförandet av nya byggnader blev det den 1 januari 2022 obligatoriskt att genomföra klimatdeklaration av nya byggnader som kräver bygglov, med vissa undantag (Boverket, 2021a). Klimatdeklarationen ska redovisa klimatpåverkan från