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2D effects in laminar premixed flames stabilized on a flat flame burner

In the present work non-idealities of flat burner-stabilized flames at atmospheric and low pressures are examined using PIV measurements, which are supported by and analyzed with the help of CFD modeling. Radial and axial velocity profiles measured in the cold flow and in the flames at atmospheric and at lower pressures are presented. Two possible reasons for the drop in the apparent laminar burni

International variations in hip fracture probabilities: Implications for risk assessment

It is recommended that intervention thresholds should be based on absolute fracture risk, but there is a large variation in hip fracture incidence from different regions of the world. The aim of this study was to examine heterogeneity of hip fracture probability in different regions from recent estimates of hip fracture incidence and mortality to adjust intervention thresholds. Ten-year probabilit

A general approach to the apparent permeability index

The apparent permeability index is widely used as part of a general screening process to study drug absorption, and is routinely obtained from in vitro or ex vivo experiments. A classical example, widely used in the pharmaceutical industry, is the in vitro Caco-2 cell culture model. The index is defined as the initial flux of compound through the membrane (normalized by membrane surface area and d

Site-Selective Participator Decay of Core-Excited Butadiene

The decay of core-excited electronic states in free 1,3 trans butadiene molecules has been studied using high-resolution synchrotron radiation and electron spectrometry. The core-level energy shift between the terminal and central carbon atoms is 0.64 eV making selective excitation of core electrons from these atoms possible. Resonant excitation to the au(*) valence state leads to autoionizing dec

Long-term efficacy of early versus delayed radiotherapy for low-grade astrocytoma and oligodendroglioma in adults: the EORTC 22845 randomised trial

Background Postoperative policies of "wait-and-see" and radiotherapy for low-grade glioma are poorly defined. A trial in the mid 1980s established the radiation dose. In 1986 the EORTC Radiotherapy and Brain Tumor Groups initiated a prospective trial to compare early radiotherapy with delayed radiotherapy. An interim analysis has been reported. We now present the long-term results. Methods After s

Lignin engineering in field-grown poplar trees affects the endosphere bacterial microbiome.

Cinnamoyl-CoA reductase (CCR), an enzyme central to the lignin biosynthetic pathway, represents a promising biotechnological target to reduce lignin levels and to improve the commercial viability of lignocellulosic biomass. However, silencing of the CCR gene results in considerable flux changes of the general and monolignol-specific lignin pathways, ultimately leading to the accumulation of variou

Walking capacity of children with clubfeet in primary school: something to worry about?

Although the main aim of clubfoot correction is to create a foot without limitations in daily activities and sport, studies on the walking capacity of children with corrected clubfeet are rare. In this cross-sectional study, the outcome of the six-minute walking test in 44 children with clubfeet (16 unilateral and 28 bilateral, mean age 8.57±2.45 years) was compared with the reference values of Ge

Epigenetic alterations in human liver from subjects with type 2 diabetes in parallel with reduced folate levels.

Epigenetic variation may contribute to the development of complex metabolic diseases such as type 2 diabetes (T2D). Hepatic insulin resistance is a hallmark of T2D. However, it remains unknown if epigenetic alterations take place in the liver from diabetic subjects. Therefore, we investigated the genome-wide DNA methylation pattern in the liver from subjects with T2D and non-diabetic controls and

Nanofiltration at elevated temperatures: Influence of the combined effects of temperature, salts, pH and cleaning

The influence of temperature, salts, pH, and various pre-treatments and cleaning on the nanofiltration (NF) performance of thin-film polyamide (PA) composite membranes has been investigated. The change in membrane performance was correlated to membrane swelling or/and electroviscous friction. Aspects of costs and energy demand while using NF at elevated temperatures were also evaluated. The increa

Self-assembly of a hydrophobically modified naphthalene-labeled poly(acrylic acid) polyelectrolyte in water: Organic solvent mixtures followed by steady-state and time-resolved fluorescence

The solution properties of two water-soluble polymers, poly(acrylic acid) (PAA), covalently labeled with the fluorescent hydrophobic dye naphthalene (Np), have been investigated in water:organic solvent mixtures. The naphthalene chromophores have been randomly attached, onto the polymer, with two different degrees of labeling. Fluorescence measurements (steady-state and time-resolved) have been us

Intervention thresholds for osteoporosis in men and women: a study based on data from Sweden

The aim of this study was to determine the threshold of fracture probability at which interventions became cost-effective in men and women, based on data from Sweden. We modeled the effects of a treatment costing $500 per year given for 5 years that decreased the risk of all osteoporotic fractures by 35% followed by a waning of effect for a further 5 years. Sensitivity analyses included a range of

Geminate charge recombination in alternating polyfluorene Copolymer/Fullerene blends

By measuring excited state and charge dynamics in blends of an alternating polyfluorene copolymer and fullerene derivative over nine orders in time and two orders in light intensity, we have monitored the light-induced processes from ultrafast charge photogeneration to much slower decay of charges by recombination. We find that at low light intensities relevant to solar cell operation relatively f

Novel gamma-carboxyglutamic acid-containing peptides from the venom of Conus textile

The cone snail is the only invertebrate system in which the vitamin K-dependent carboxylase (or gamma-carboxylase) and its product gamma-carboxyglutamic acid (Gla) have been identified. It remains the sole source of structural information of invertebrate gamma-carboxylase substrates. Four novel Gla-containing peptides were purified from the venom of Conus textile and characterized using biochemica

Functional, structural and evolutionary studies on a family of bacterial surface proteins

Popular Abstract in Swedish Hos människan lever en rad mikroorganismer som tillsammans utgör normalfloran. Normalfloran återfinns på alla kroppsytor, det vill säga huden och slemhinnorna i munnen, svalget, magsäcken, tunn- och tjocktarmen, vagina och urinrörsmynningen. Samspelet mellan människokroppen och mikroorganismerna utsätts dagligen för påfrestningar. En sådan naturlig påfrestning är de sjuThis thesis is concerned with a family of bacterial surface proteins expressed by different strains of the anaerobic Gram-positive, commensal and human pathogen Peptostreptococcus magnus. These proteins have been studied with respect to their role in virulence, function, structure, and evolution. Strains isolated from patients with vaginosis have previously been shown to be associated with express

Key aspects of free and open source enterprise resource planning systems

This chapter introduces basic differences between Free/Open Source Enterprise Resources Planning systems (FOS-ERP) and Proprietary ERP (P-ERP), revisiting the previous work of Carvalho (2008). Taking into account that some years has passed and the economic downturn came, it updates key aspects of FOS-ERP under both vendor and adopter perspectives. Like its predecessor, this chapter contributes to

U-Pb geochronology of the Tsineng dyke swarm and paleomagnetism of the Hartley Basalt Formation, South Africa : evidence for two separate magmatic events at 1.93 – 1.92 and 1.88 – 1.84 Ga in the Kalahari craton

Geokronologi och paleomagnetiska studier är de viktigaste verktygen för paleogeografiska rekonstruktioner kring hur kontinenter fårhållit sig relativt till varandra under geologisk tid. Genom att jämföra s.k. polvandringskurvor och tidpunkter för storskaliga magmatiska händelser mellan olika krustala block (kontienter/kratoner) kan vi få en bättre förståelse av hur dessa block förhöll sig relativtRobust geochronology and well-constrained paleopoles are the main tools for paleogeographic reconstructions. Through the completion of so called barcode diagrams (matching of coeval events of mafic magmatism between blocks) and determination of the apparent polar wander paths, these studies provide a better understanding of the position of continents and supercontinents in the past. The robust U–P

The Right to be (Un)Seen - Means for Enactment of Human Rights in Situations of Encampment

The implementation of iris scan technology in the context of humanitarian financial assistance in UNHCR-run refugee camps raises an array of legal questions. While the collection and storage of biometrical data in other contexts is often accompanied by a critical discussion about data protection and privacy concerns, the use of such data in humanitarian settings is often left uncontested. The in-d

Dynamically predicted shelf-life label in minced meat product: A consumer-driven design and analysis

Dynamically predicted shelf-life label (DPSL) has been discussed to be one of the solutions to curb meat waste. Therefore, the research about the DPSL label and the perceptible information obtained by minced meat consumers is conducted. The research purpose is to identify the critical factors to design a DPSL label for minced meat consumers, and to design and assess the label with the consumers. T