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Studies on hereditary C2 deficiency: Frequent occurrence of severe infections, atherosclerosis and rheumatological manifestations

Popular Abstract in Swedish Komplementsystemet utgör en del av den medfödda immuniteten och är viktigt i försvaret mot angripande mikroorganismer. Ärftlig C2-brist (C2D) är en av de vanligaste bristerna inom komplementsystemet och förekommer i en frekvens av 1: 20 000 hos personer med västerländsk härstamning. I de aktuella undersökningarna har mer än 40 personer med C2D identifierats och observerThe complement system is a part of the innate immunity and is essential in the defence against microorganisms. Hereditary C2 deficiency (C2D) is one of the most common complement deficiency states with an estimated prevalence of 1:20,000 in persons of Western descent. In the present investigation, the identification of more than 40 C2D persons at a single centre combined with long observation peri

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Vart fjärde år, i valtider, uppstår en viss typ av kommunikation då och enbart då. Valaffischer trycks än idag i stora upplagor och sätts upp vid valda platser i hela Sverige, vilket leder till en stor exponering hos invånarna. Denna stora uppvisning har dock inte lett till någon större forskningsinsats på valaffischer, utan det finns ett mycket smalt utbud av studier av svenska valaffischer. ForEvery fourth year at, during elections, a certain type of communication appears. Election posters are still today printed in large quantities and placed at locations all throughout Sweden, which entails a large exposure to the inhabitants. Yet, this display has not lead to a great amount of research on election posters, but there is a small number of studies of Swedish election posters. Research

Eligibility Form LUSEM LTH N 2025

Microsoft Word - Eligibility form - new version Eligibility form This eligibility form is compulsory to fill out for any exchange student who wishes to apply for courses with prerequisites at the Lund University School of Economics and Management (LUSEM) and the Faculty of Science, or courses in Engineering at the Faculty of Engineering (LTH). Required information: Name: __________________________

https://www.science.lu.se/sites/science.lu.se/files/2025-03/Eligibility_Form_LUSEM_LTH_N_2025.pdf - 2026-05-30

Growth and Resilience Theory: A new way of conceptualising convergence dynamics.

Recent studies have highlighted how building resilience to ‘shrinking’ episodes, as opposed to increasing growth rates, appears to be the missing piece of the puzzle when it comes to between-country income convergence. All economies seem to be able to grow, but few countries have been able to drastically improve their shrinking patterns, which has underpinned the divergence often argued in literat

Structural determination of Streptococcus pyogenes M1 protein interactions with human immunoglobulin G using integrative structural biology

Streptococcus pyogenes (Group A streptococcus; GAS) is an important human pathogen responsible for mild to severe, life-threatening infections. GAS expresses a wide range of virulence factors, including the M family proteins. The M proteins allow the bacteria to evade parts of the human immune defenses by triggering the formation of a dense coat of plasma proteins surrounding the bacteria, includi

Efficacy of T-cell assays for the diagnosis of primary defects in cytotoxic lymphocyte exocytosis

Primary hemophagocytic lymphohistiocytosis (HLH) is a life-threatening disorder associated with autosomal recessive variants in genes required for perforin-mediated lymphocyte cytotoxicity. A rapid diagnosis is crucial for successful treatment. Although defective cytotoxic T lymphocyte (CTL) function causes pathogenesis, quantification of natural killer (NK)–cell exocytosis triggered by K562 targe

Group G streptococcal IgG binding molecules FOG and protein G have different impacts on opsonization by C1q

Recent epidemiological data on diseases caused by beta-hemolytic streptococci belonging to Lancefield group C and G ( GCS, GGS) underline that they are an emerging threat to human health. Among various virulence factors expressed by GCS and GGS isolates from human infections, M and M-like proteins are considered important because of their anti-phagocytic activity. In addition, protein G has been i

Stem Cell Talk with Prof. Anna Falk: 'Induced Pluripotent Stem Cells and Cell Therapy'

25 mars 2026 15:00 till 16:00 | Seminarium Lund Stem Cell Center invites you to join our first Stem Cell Talk of 2026, on 25 March, featuring Principal Investigator Anna Falk! This event is open to all students and researchers at Lund University. No registration required. Our monthly Stem Cell Talks offer a dynamic platform for Lund Stem Cell Center's Principal Investigators to present their resea

https://www.medicin.lu.se/evenemang/stem-cell-talk-prof-anna-falk-induced-pluripotent-stem-cells-and-cell-therapy - 2026-05-30

Stem Cell Talk with Christopher Douse: 'Epigenetic control of the repetitive genome'

20 maj 2026 15:00 till 16:00 | Seminarium Lund Stem Cell Center invites you to join our next Stem Cell Talk, on 20 May featuring Associate Professor Christopher Douse. This event is open to all students and researchers at Lund University. No registration required. Our monthly Stem Cell Talks offer a dynamic platform for Lund Stem Cell Center's Principal Investigators to present their research and

https://www.medicin.lu.se/evenemang/stem-cell-talk-christopher-douse-epigenetic-control-repetitive-genome - 2026-05-30

Streptococcus pyogenes secreted enzymes interacting with the human host

Streptococcus pyogenes is one of the most common bacteria infecting humans. One of the factors contributing to the disease-causing properties is the secreted streptococcal cysteine proteinase, SpeB, which degrades several host proteins in connective tissue and circulation. SpeB activity depends on the transformation from an inactive precursor, zymogen, into a mature proteinase. We show that

Development and validation of a novel Simoa assay for NPTX2 in Alzheimer's disease and Down syndrome

INTRODUCTION: Synaptic dysfunction and loss are pathological hallmarks of neurodegenerative diseases. Neuronal pentraxin 2 (NPTX2), a presynaptic protein involved in synaptic plasticity, has been linked to cognitive decline in Alzheimer's disease (AD) and other neurodegenerative disorders. METHODS: We developed and validated a novel single molecule array (Simoa) for NPTX2 in cerebrospinal fluid, w

Potentialities of manganese ore and iron-carbon particles for pharmaceuticals and personal care products removal in electroactive constructed wetland

This study explores the use of manganese ore, iron-carbon particles (Fe-C), and gravel as anode fillers in electroactive constructed wetlands (ECWs) to treat wastewater containing pharmaceuticals and personal care products (PPCPs) including ciprofloxacin (CIP), ofloxacin (OFL), and naproxen (NPX), while also assessing bioelectricity production. Although the presence of PPCPs reduced pollutant remo

Defining extended half-life rFVIII-A critical review of the evidence

Introduction: Recent haemophilia treatment advances include new recombinant FVIII (rFVIII) products with improved pharmacokinetic (PK) properties that aim to reduce the burden of prophylaxis. These treatments are commonly referred to as extended half-life rFVIII products (EHL rFVIII). There is no uniform definition of what constitutes an EHL rFVIII. Such a definition would help physicians, patient

The purchasing process

Here you can read about various steps in the purchasing process, such as who does what, the order system, delivery, registration of chemicals, and facility assets. Who does what?KC Purchasing handles the purchase of:ChemicalsBiological and biomedical products Lab products (glass, plastic, etc.)Laboratory equipmentGasIT products (computers, computer accessories, etc.)Office suppliesCoffee, tea, mil

https://www.kilu.lu.se/en/internal/support-and-tools/purchase/purchasing-process - 2026-05-29

Forteckning over historiska handlingar 0

Förteckning över De la Gardieska arkivet Historiska handlingar reviderad 2009 av Per Stobaeus Universitetsbiblioteket, Lunds universitet 2 Bild på framsidan: Gustav II Adolfs fullmakt för Hans Eckholt att vara överste över ett finskt rytteriregemente, Neuburg 1632-10-07 (HH 3:1). De foton på dokument i Historiska handlingar som ingår i denna förteckning är tagna av UB-Media. 3 DE LA GARDIESKA ARKI

https://www.ub.lu.se/en/sites/ub.lu.se.en/files/forteckning_over_historiska_handlingar_0.pdf - 2026-05-30

Etablering-av-doktorand-i-Ladok-sv-eng-2303

Etablering av doktorand i Ladok. Admission of post graduate student in LADOK. 1/1 Etablering av doktorand i Ladok / Admission of post graduate student in LADOK Uppgifter om antagen doktorand / Personal data of admitted post graduate student Personnummer / Personal identity number (or date of birth) Efternamn, förnamn / Last name, first name Personnummer anges enligt YYYYMMDD-NNNN. Om svenskt perso

https://www.medarbetarwebben.lu.se/sites/medarbetarwebben.lu.se/files/2023-03/Etablering-av-doktorand-i-Ladok-sv-eng-2303.pdf - 2026-05-30