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Inhibition of coxsackie B virus infection by soluble forms of its receptors: Binding affinities, altered particle formation, and competition with cellular receptors

We previously reported that soluble decay-accelerating factor (DAF) and coxsackievirus-adenovirus receptor (CAR) blocked coxsackievirus 133 (CVB3) myocarditis in mice, but only soluble CAR blocked CVB3-mediated pancreatitis. Here, we report that the in vitro mechanisms of viral inhibition by these soluble receptors also differ. Soluble DAF inhibited virus infection through the formation of reversi

Changes in resting-state functional connectivity after stroke in a mouse brain lacking extracellular matrix components

In the brain, focal ischemia results in a local region of cell death and disruption of both local and remote functional neuronal networks. Tissue reorganization following stroke can be limited by factors such as extracellular matrix (ECM) molecules that prevent neuronal growth and synaptic plasticity. The brain's ECM plays a crucial role in network formation, development, and regeneration of the c

Phase 1/2a clinical trial of BI-1206, an anti-CD32b (FcγRIIB) antibody, in combination with pembrolizumab in subjects with advanced solid tumors previously treated with anti-PD-1/PD-L1.

2593Background: PD-1 blockade has demonstrated positive anti-tumor activity across multiple tumor types. While the anti-tumoral response can be substantial and even curative, response rates remain low in many cancer types. Long-lasting responses are only observed in a minority of patients, and additional immunotherapeutic alternatives remain limited for patients who fail to respond or initially re

Trade and World Power: A model for a Time-Space Appropriation Assessment of an 18 th Century Swedish-Chinese-Spanish(-American) Trade Exchange

Trade and World Power: A Time-Space Appropriation Assessment of an 18th Century Swedish-Chinese-Spanish(-American) Trade Exchange Was China rather than Europe the center of the early modern world system, as claimed by so-called new world historians such as Kenneth Pomeranz and Andre Gunder Frank? Can structural position within the hierarchy of the world system be revealed through assessment of ec

nyhetsbrev_07.docx

nyhetsbrev_07.docx Nyhetsbrev från Akademikerföreningen Sveriges Ingenjörer vid Siemens Energy AB Kontakt: asi.se@siemens-energy.com Redaktörer: SvE, CH, JB, SJ Nr: 07/24 2024-10-10 Avbröt du din semester på företagets begäran? Vi vill påminna om ersä ningen vid avbruten, sedan digare godkänd, semester. Blev du llfrågad av företaget a avbryta din semester och gick med på det så har du rä ll 1750 k

https://www.saco.se/globalassets/lokala-akademikerforeningar/privat/siemens-energy-ab/nyhetsbrev/asi-nyhetsbrev-0724.pdf - 2026-05-26

Emilia Ängeby -Institutionen för kliniska vetenskaper, Lund

15 maj 2025 12:00 | Halvtidskontroll Title: Methods for quality assurance and decreasing complications after central venous catheterisation.Main supervisor: Thomas Kander M.D., PhD, ProfessorReviewers: Hans Friberg M.D. Professor & Anna Lybeck M.D., Associate ProfessorAbstractBackgroundCentral venous catheters are essential in modern healthcare but come with risks. Mechanical complications occur w

https://www.intramed.lu.se/evenemang/emilia-angeby-institutionen-kliniska-vetenskaper-lund - 2026-05-27

ICOS-ligand triggering impairs osteoclast differentiation and function in vitro and in vivo

Osteoblasts, osteocytes, and osteoclasts (OCs) are involved in the bone production and resorption, which are crucial in bone homeostasis. OC hyperactivation plays a role in the exaggerated bone resorption of diseases such as osteoporosis, rheumatoid arthritis, and osteolytic tumor metastases. This work stems from the finding that OCs can express B7h (ICOS-Ligand), which is the ligand of the ICOS T

Brutal Need : Lawyers and the Welfare Rights Movement, 1960-1973 - The Raoul Wallenberg Institute of

Brutal Need : Lawyers and the Welfare Rights Movement, 1960-1973 - The Raoul Wallenberg Institute of Human Rights and Humanitarian Law Skip to content Search for: Search Button Home About Us Who We Are Our History About Raoul Wallenberg Our Theory of Change Staff Opportunities Annual Reports Whistleblower Our work What we do Multi-Disciplinary Research Higher Education Strategic Advice and Analysi

https://rwi.lu.se/publications/brutal-need-lawyers-and-the-welfare-rights-movement-1960-1973/ - 2026-05-25

“The Politics of Sexual Health in Vietnam” - The Raoul Wallenberg Institute of Human Rights and Huma

“The Politics of Sexual Health in Vietnam” - The Raoul Wallenberg Institute of Human Rights and Humanitarian Law Skip to content Search for: Search Button Home About Us Who We Are Our History About Raoul Wallenberg Our Theory of Change Staff Opportunities Annual Reports Whistleblower Our work What we do Multi-Disciplinary Research Higher Education Strategic Advice and Analysis Outreach Evaluation

https://rwi.lu.se/publications/the-politics-of-sexual-health-in-vietnam/ - 2026-05-26

Courts and Democracy in a One-Party State: Judicial Independence in China - The Raoul Wallenberg Ins

Courts and Democracy in a One-Party State: Judicial Independence in China - The Raoul Wallenberg Institute of Human Rights and Humanitarian Law Skip to content Search for: Search Button Home About Us Who We Are Our History About Raoul Wallenberg Our Theory of Change Staff Opportunities Annual Reports Whistleblower Our work What we do Multi-Disciplinary Research Higher Education Strategic Advice an

https://rwi.lu.se/publications/courts-and-democracy-in-a-one-party-state-judicial-independence-in-china/ - 2026-05-26

Menneskerettigheder presser Fort Europa - The Raoul Wallenberg Institute of Human Rights and Humanit

Menneskerettigheder presser Fort Europa - The Raoul Wallenberg Institute of Human Rights and Humanitarian Law Skip to content Search for: Search Button Home About Us Who We Are Our History About Raoul Wallenberg Our Theory of Change Staff Opportunities Annual Reports Whistleblower Our work What we do Multi-Disciplinary Research Higher Education Strategic Advice and Analysis Outreach Evaluation of

https://rwi.lu.se/publications/menneskerettigheder-presser-fort-europa/ - 2026-05-26

Systemic sclerosis. Novel molecular and epidemiological features of disease.

Popular Abstract in Swedish Systemisk skleros (SSc) är en relativt ovanlig reumatologisk sjukdom som kan engagera många av kroppens organ. Sjukdomen kallas ibland också för sklerodermi. Typiskt för sjukdomen är att huden omvandlas till fibros och blir hård och stram över olika delar av kroppen. Typiskt för sjukdomen är också att drabbade patienter har försämrad funktion i sina blodkärl, framförallSystemic sclerosis (SSc) is a systemic rheumatic disease with significant mortality and morbidity. Different estimations of disease prevalence and incidence have been presented from various parts of the world. While lung involvement is a common cause of SSc-related death, a majority of SSc patients suffer from symptoms originating in the gastrointestinal (GI) tract. By combining data from a popu