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Performance of the European Society of Cardiology 0/1-Hour, 0/2-Hour, and 0/3-Hour Algorithms for Rapid Triage of Acute Myocardial Infarction : An International Collaborative Meta-analysis

BACKGROUND: The 2020 European Society of Cardiology (ESC) guidelines recommend using the 0/1-hour and 0/2-hour algorithms over the 0/3-hour algorithm as the first and second choices of high-sensitivity cardiac troponin (hs-cTn)-based strategies for triage of patients with suspected acute myocardial infarction (AMI).PURPOSE: To evaluate the diagnostic accuracies of the ESC 0/1-hour, 0/2-hour, and 0

Interactions between β-haemolytic streptococci and the human host. Heart, skin and beyond.

Group C and G streptococci (GCS/GGS) and group A streptococci (GAS) belong to β-haemolytic streptococci (BHS). GCS/GGS can further be species determined to S. dysgalactiae, whereas S. pyogenes are GAS. S. dysgalactiae and S. pyogenes cause similar diseases, (e.g., skin and soft tissue infections, erysipelas, bacteraemia, and infective endocarditis (IE)). Erysipelas often presents as a sharply dema

Non-invasive detection of c-myc p64, c-myc p67 and c-erbb-2 in colorectal cancer

Objective. Colorectal cancer is a major cause of cancer mortality in the industrialized nations in the West. Because mortality is closely related to the stage of the disease at the time of diagnosis, detection at an early stage is likely to result in improved recovery rates. Since current diagnostic procedures such as colonoscopy are invasive and the fecal occult blood test (FOBT) lacks sensitivit

Training artificial neural networks directly on the concordance index for censored data using genetic algorithms.

OBJECTIVE: The concordance index (c-index) is the standard way of evaluating the performance of prognostic models in the presence of censored data. Constructing prognostic models using artificial neural networks (ANNs) is commonly done by training on error functions which are modified versions of the c-index. Our objective was to demonstrate the capability of training directly on the c-index and t

Assessing the effects of mining projects on child health in sub-Saharan Africa : a multi-country analysis

Background: The African continent hosts many industrial mining projects, and many more are planned due to recent prospecting discoveries and increasing demand for various minerals to promote a low-carbon future. The extraction of natural resources in sub-Saharan Africa (SSA) represents an opportunity for economic development but also poses a threat to population health through rapid urbanisation a

Use of Barley in Development of a Functional Product with Low Glycaemic Index

Diet is considered one of the key factors contributing to an increased risk of developing diabetes type 2. The rising prevalence of this condition is alarming and highlights the urgent need for effective nutrition-based strategies to alleviate an impending health crisis. As reoccurring hyperglycaemic episodes have been linked to an increased risk of becoming a diabetic, there is an opportunity for

ACCOUNTING EDUCATION IN VIETNAM THROUGH THE LENSES OF LEGITIMACY THEORY AND STAKEHOLDER THEORY

Seminar date: 30 May 2013 Course: BUSN69 – Degree Project in Accounting and Auditing Authors: Alex Trung Huỳnh and Thảo Trần Supervisors: Anne Loft and Maria Bengtsson Key words: accounting education, university, Vietnam, employability, legitimacy, stakeholders. Background and problem: Since Đổi Mới, the Economic Reformation, in 1986, Vietnam has seen a huge improvement in terms of economic d

Kinesiska skolmjölksprogrammet – Förutsättningar för en framtida leverantör

Oatly is a company that produces and sells oat based products. Their most selling product is the oat drink, which is a substitute to milk, and over 80 percent of the annual sales volume comes from this product. Since the foundation of Oatly, the main idea has been to sell their products on markets with low milk availability and milk consumption. Most recently, Oatly identified the Chinese market a

A comprehensive study on dynamics of flames in a nanosecond pulsed discharge. Part I: Discharge formation and gas heating

Nanosecond pulsed discharges (NPD) have been extensively used in plasma-assisted combustion to stimulate combustion kinetics. Experimental measurement of the energy transfer processes in non-equilibrium plasma-assisted processes is extremely difficult, as the non-equilibrium plasma discharge involves numerous different species with transient and complex three-dimensional structures across various

Diagnostic accuracy of the Scandinavian guidelines for minor and moderate head trauma in children : a prospective, pragmatic, validation study

Background: Current guidelines for initial management of traumatic brain injury (TBI) support decision making, but they are rarely validated. The Scandinavian guideline for management of children with TBI (SNC16) was developed to minimise the use of cranial computed tomography (cCT) without compromising safety, but the performance of the guideline in a real-world population is unknown. We aimed to

Orthostatic hypotension in genetically related hypertensive and normotensive individuals.

OBJECTIVES: Prevalence and determinants of orthostatic hypotension remain largely unexplored in younger individuals without significant burden of chronic diseases. METHODS: We investigated frequency and main associations of impaired orthostatic response in a cohort of 469 middle-aged hypertensive patients and 453 of their normotensive first-degree relatives. RESULTS: 13.4% of hypertensive and 5.5%

Poor adult tuberculosis treatment outcome and associated factors in Gibe Woreda, Southern Ethiopia : An institution-based cross-sectional study

Tuberculosis (TB) remains a major medical and public health problem throughout the world, especially in developing countries including Ethiopia. Its control program is currently being challenged by the spread of drug-resistant TB, which is the result of poor treatment outcomes. Hence, this study assessed poor adult TB treatment outcomes and associated factors in Gibe Woreda, Southern Ethiopia. An

Can a Dinosaur Think? Implementation of Artificial Intelligence in Extracorporeal Shock Wave Lithotripsy

Background: Extracorporeal shock wave lithotripsy (ESWL) of kidney stones is losing ground to more expensive and invasive endoscopic treatments. Objective: This proof-of-concept project was initiated to develop artificial intelligence (AI)-augmented ESWL and to investigate the potential for machine learning to improve the efficacy of ESWL. Design, setting, and participants: Two-dimensional ultraso

The role of biogeophysical feedbacks and their impacts in the arctic and boreal climate system

De nordliga höga latitudernas fysiska miljö, inklusive kryosfären i Arktis, har genomgått dramatiska förändringar under de senaste decennierna tack vare uppvärmning och andra klimatförändringar kopplade till antropogena utsläpp av växthusgaser. Uppvärmningen i regionen är ungefär det dubbla jämfört med ökningen i medeltemperaturen globalt. Globala klimatmodeller förutspår att denna förstärkta uppvThe physical environment in the northern high latitudes including the Arctic cryosphere has undergone dramatic changes due to anthropogenic greenhouse gas warming, which since pre-industrial times has been twice or more the rate of global mean warming. Global climate models predict that this accelerated warming will continue for at least the next few decades. Meanwhile, the arctic and subarctic ve

Caldicellulosiruptor Saccharolyticus: an Ideal Hydrogen Producer?

Popular Abstract in English What is common between the science of physics and global politics? They both define power in terms of energy. Indeed, the uneven distribution of petroleum reserves has been one of the main reasons of social, political and economic problems worldwide. Even more worrying is the rapid increase in the levels of greenhouse gases in the atmosphere. This is mainly caused by ouCaldicellulosiruptor saccharolyticus is an extremely thermophilic, strictly anaerobic, Gram-positive and cellulolytic microorganism with a natural ability to produce hydrogen (H2) at nearly theoretical maximum yield, i.e. 4 mol/ mol of glucose. Due to its CO2-free combustion and high energy density, among other desirable properties, H2is touted as a fuel of the future. Biological H2 production b

Priming effects induced by glucose and decaying plant residues on SOM decomposition : A three-source 13C/14C partitioning study

Decomposition of soil organic matter (SOM) may either increase or decrease after fresh organic inputs, the phenomena which are termed as “priming effect”. Crop residues and labile C additions can prime SOM decomposition, but it is not known how labile C inputs affect SOM in the presence of decaying plant residues varying in quality (e.g. from previous crops, a common situation in arable soils). We

Evaluating the Potential of Southampton Carbon Flux Model (SCARF) for Monitoring Terrestrial Gross Primary Productivity Across African Ecosystems

Accurate knowledge about the amount and dynamics of terrestrial gross primary productivity is an important component for understanding of ecosystem functioning and processes. Recently a new diagnostic model, Southampton Carbon Flux (SCARF), was developed to predict terrestrial gross primary productivity at regional to global scale based on a chlorophyll index derived from MERIS data. The model aim

Sensory system integration of the designed mechatronics Touch Hand

Purpose - This paper aims to explore the electronic design of the Touch Hand: a low-cost electrically powered prosthetic hand. The hand is equipped with an array of sensors allowing for position control and haptic sensation. Pressure sensors are used on the fingertips to detect grip force. A temperature sensor placed in the fingertip is used to measure the contact temperature of objects. Investiga

Holocene land cover change in North America : Continental trends, regional drivers, and implications for vegetation-atmosphere feedbacks

Land cover governs the biogeophysical and biogeochemical feedbacks between the land surface and atmosphere. Holocene vegetation-atmosphere interactions are of particular interest, both to understand the climate effects of intensifying human land use and as a possible explanation for the Holocene temperature conundrum, a widely studied mismatch between simulated and reconstructed temperatures. Prog

Imaging evaluation focused on microstructural tissue changes using tensor-valued diffusion encoding in breast cancers after neoadjuvant chemotherapy : is it a promising way forward?

Background: Single diffusion encoding is a widely used, noninvasive technique for probing the tissue microstructure in breast tumors. However, it does not provide detailed information about the microenvironmental complexity. This study investigated the clinical utility of tensor-valued diffusion encoding for evaluating microstructural changes in breast cancer after neoadjuvant chemotherapy (NAC).