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Popular Abstract in Swedish Sjögrens syndrom är en autoimmun sjukdom, vilket betyder att immunsystemet felreagerar och angriper kroppens egen vävnad. Nittio procent av dem som får diagnosen är kvinnor, av vilka de flesta är mellan 40 och 60 år. Vid Sjögrens syndrom, som tillhör en av våra vanligaste reumatiska sjukdomar, är det framförallt tår- och spottkörtlar som angrips och blir inflammerade. DPrimary Sjögren’s syndrome (SS) is a chronic autoimmune disease of unknown etiology. The disease primarily involves lachrymal and salivary glands, leading to dryness of the eyes and mouth, but a wide spectrum of exocrine and non-exocrine disease manifestations may be seen. A characteristic property of primary SS is the production of autoantibodies directed against intracellular, often DNA/RNA-modi

Popular Abstract in Swedish Populärvetenskaplig sammanfattning Parkinson's sjukdom är näst efter Alzheimer's sjukdom den vanligast förekommande neurologiska sjukdomen. Parkinson's är en förhållandevi's vanlig neurologisk sjukdom och det finn's belägg för den i alla kulturer där sjukdomsstatistik för's. I Sverige lever idag cirka 20 000 personer med sjukdomen. Förekomsten av sjukdomen är starkt åAbstract Aims: The aim of this thesis was to investigate how the impact of Parkinson’s disease, a chronic neurodegenerative disorder, influences the person’s health-related quality of life. The aim was also to investigate nursing assessment and management of Parkinson’s in elderly persons. Methods: The study started in1998, one year later a follow-up was conducted. The sample contained in the fir

Vind har blivit en alltmer accepterad källa till förnyelsebar energi och utnyttjas idag världen över. Vindenergi har fördelen av nästintill inga utsläpp av växthusgaser, men allmänheten har i vissa uttryckt oro över det buller som associeras med vindkraftverk. For att möta detta missnöje har kommuner infört föreskrifter som begränsar ljudnivåerna vid bostadshus belägna i närheten av vindkraftverk.Wind has become an increasingly accepted source of renewable energy and is currently exploited worldwide. Wind energy has the advantage of close to zero green-house gas emissions, however one of the key concerns the public has about wind farm development is noise emissions. To address these local governments have introduced noise regulations, which limit noise levels at residential buildings locat

Enligt svensk familjerätt är syskons rätt till varandra varken en fastslagen lag eller utvecklad i förarbeten och doktrin. Trots detta föreligger det ett starkt skydd av syskon enligt praxis, vilken har sin grund i begreppet kontinuitet. Begreppet kontinuitet är ett resultat av främst praxis, men har sin grund i förarbeten. Denna har till syfte att behålla all slags pågående kontinuitet för barnetAccording to Swedish family law, the right for siblings to each other is not a stated rule, nor well developed in preliminary works or doctrine. However, there is a higher level of protection of siblings according to case law, which is anchored in the concept of continuity. The concept of continuity is mainly a result from case law, but has its ground in preliminary work. It aims to maintain all c

Prostatacancer är den vanligaste cancern bland män i Sverige. Varje år insjuknar ca 10 000. Sjukdomen är starkt åldersberoende och är mycket vanlig bland äldre män. Latent cancer (icke kliniskt signifikant) förekommer ofta. Sjukdomen klassificeras som låg, mellan eller högrisk baserat på Gleason summa (tumörens aggressivitet), stadium och PSA. Val av behandling sker utifrån riskgrupp och ålder. LåAbstract Backgound Prostate cancer is the most common form of cancer in men in Sweden. Radiotherapy, including external beam radiation therapy (EBRT) and brachytherapy (BT), is important treatment alternatives to surgery and active surveillance. Precise delivery of the prescribed absorbed dose to the prostate with minimal irradiation of normal tissue, specifically organs at risk, is crucial for op

Under årens lopp har människan gjort stora landvinningar inom läkemedelsforskning, vilket har lett fram till avancerade läkemedel som idag tas för givna. Avancerade läkemedel sätter dock höga krav på tillverkarna av läkemedel, vilket har lett till att framtagandet av nya läkemedel är en ganska komplicerad process. Faktum är att dagens läkemedelsutveckling är så komplex att alla aspekter förmodligePopular Abstract in Swedish Under årens lopp har människan gjort stora landvinningar inom läkemedelsforskning, vilket har lett fram till avancerade läkemedel som idag tas för givna. Avancerade läkemedel sätter dock höga krav på tillverkarna av läkemedel, vilket har lett till att framtagandet av nya läkemedel är en ganska komplicerad process. Faktum är att dagens läkemedelsutveckling är så komplex

Northern ecosystems, encompassing boreal forests, tundra, and permafrost areas, are increasingly affected by the amplified impacts of climate change. These ecosystems play a crucial role in determining the global carbon budget. To improve our understanding of carbon uptake in these regions, we evaluate the effectiveness of employing the physically-based Plant Phenology Index (PPI) to estimate gros

Dune slacks are biodiverse seasonal wetlands within sand dune systems, strongly influenced by the dynamics of the local groundwater regime. Future climate predictions indicate strong adverse impact on the hydrology and therefore ecology of these wetland ecosystems. In this study we aimed to find the most appropriate hydrological and ecological indicators to summarise dune slack plant community res

The Veiki moraine in northern Sweden, a geomorphologically distinct landscape of ice-walled lake plains, has been interpreted to represent the former margin of an intermediate-sized pre–Last Glacial Maximum (LGM) Fennoscandian ice sheet, but its age is debated as either marine isotope stage (MIS) 5c or MIS 3. We have applied optically stimulated luminescence (OSL) and radiocarbon dating to four si

The design of port complexes is a process that requires considering geographical and economic features of the territory. It is necessary to aggregate the characteristics of coastal landscapes, seascapes, artificial elements, dangerous objects, etc. The experience of implementing such projects (for example, in Sabetta) suggests that all participants in the design process need highly precise geograp

Introduction: Due to the high cost and complexity, the oral glucose tolerance test is not adopted as the screening method for identifying diabetes patients, which leads to the misdiagnosis of patients with isolated post-challenge hyperglycemia (IPH), that is., patients with normal fasting plasma glucose (<7.0 mmoL/L) and abnormal 2-h postprandial blood glucose (≥11.1 mmoL/L). We aimed to develop a

[NiFe] hydrogenases catalyse the reaction H2 <-> 2H(+) + 2e(-). Several states of the enzyme have been observed by spectroscopic methods. Among these, the two most oxidized states, called the unready Ni-A and Ni-SU states, have been especially intriguing, because they take a much longer time to activate than the corresponding ready Ni-B and Ni-SI states. It has recently been suggested that the unr

Background: A wrist-worn wearable device for acquiring limb and chest ECG leads (wECG) may constitute a promising approach to detection of acute myocardial infarction (AMI). However, it remains to be demonstrated whether the information conveyed by the wECG is sufficient for AMI detection. Objective: To explore explainable machine learning models for detecting AMI using the wECG. Methods: Two type

Gross primary production (GPP) of the vegetation is the largest carbon exchange process of the global carbon cycle. Currently, within satellite-based remote sensing, GPP is generally modelled using linear light use efficiency models where GPP is related to photosynthetically active radiation absorbed by the green vegetation (APAR). These models work well on moderate to low spatiotemporal averaging

This report examines the possibilities of decarbonising operation & maintenance vessels for a prospective floating offshore wind power park at the Utsira Nord site in Norway, through self-sufficient energy carrier production utilizing power-to-X-solutions. Possible alternative fuels are identified as compressed hydrogen, batteries, liquid hydrogen, ammonia, methanol, and biofuels, out of which

Global warming and climate change is getting a serious issue and a great environmental threat that affects many aspects of life and our ways of living on this planet. The negative effects of climate change are endangering our communities, health and economy. Global warming can be considered as a main reason for sea rising levels, extreme heat which is responsible for many forests’ fires, severe dr

For model-based quantitative reconstructions of past vegetation cover on the scale of landscapes, pollen productivity estimates (PPEs) are key input parameters. In this study, we employed a random sampling strategy to collect moss polsters at 20 sites in Changbai Mountain, northeastern China. A detailed vegetation survey within 1000-m radius around each sampling point was carried out and digitized

This thesis examines the effect of water quality, habitat and species interactions on the occurrence and abundance of stream fishes in southern Sweden. I found that improvements in water quality between the 1960s and 1990s have led to recolonization of streams by brown trout (Salmo trutta L.), stone loach (Barbatula barbatula L.) and eel (Anguilla anguilla L.). The response was greatest for brown

Estimates of relative pollen productivity (RPP) represent key input parameters for model-based quantitative reconstructions of past vegetation cover. In this study, we provide the first RPP estimates for 13 taxa from the forest steppe ecoregion in southeastern Romania (southeastern Europe). We used modern pollen assemblages from 26 points together with vegetation surveys and mapping, covering a 1.