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Prediction of Alzheimer’s disease in subjects with Mild Cognitive Impairment using biomarkers

Popular Abstract in Swedish Alzheimers sjukdom (eng. Alzheimer’s disease, AD) är den vanligaste orsaken till de- mens. Demens innebär en permanent sänkning av intellektuella förmågor som påverkar individen påtagligt i vardagen. Förekomsten av demenssjukdomar ökar betydligt efter 65 års ålder. AD är en långsamt progredierande sjukdom, som oftast börjar med försämrat närminne. Redan idag är AD en beBackground: Alzheimer’s disease (AD) is the most common cause of dementia. In order to have effect of future disease-modifying therapies for AD, the disease must be identified early, before the patients have developed dementia. Many patients with Mild Cognitive Impairment (MCI) have prodromal AD, but other causes for the syndrome are common. No diagnostic method can identify AD in patients with MC

Effects of Vagus Nerve Stimulation and Ketogenic Diet on Quality of Life and Changes in EEG and Sleep

Popular Abstract in Swedish De flesta barn som insjuknar i epilepsi tillfrisknar eller blir anfallsfria med hjälp av antiepileptisk medicin. Hos drygt en fjärde del av barnen blir epilepsin svårbehandlad och anfallskontroll är svår att uppnå. Dessa barn ska i första hand erbjudas möjlighet till epilepsikirurgisk utredning och behandling. När epilepsikirurgisk behandling inte är möjlig att utföra eWhen anti-epileptic drugs fail, and epilepsy surgery is found unfeasible or ineffective, there remains a group of at least 25% of children with epilepsy in whom seizure control cannot be achieved. Vagus nerve stimulation (VNS) is an adjunctive treatment for medically refractory epilepsy. It is an implantable, multi-programmable pulse generator that delivers current electrical stimulation to the va

In vivo properties of neural stem cells after transplantation into the rat brain-Studies of phenotypic differentiation and functional integration using cell-specific labelling and electrophysiological techniques

In the present thesis, we have examined the in vivo properties of in vitro expanded human and rat neural stem-and progenitor cells after transplantation into the neonatal and adult rat brain. The survival and differentiation of the grafted cells were assessed using species-specific antisera, and pre-labelling with the reporter gene green fluorescent protein (GFP). Long-term growth factor-expanded

Intestinal mucins 'soluble and insoluble problems'

Popular Abstract in Swedish På utsidan av insidan - slemmet i tarmen Kroppens slemhinnor, till exempel de i magsäcken och tarmen, täcks av ett slemlager. Slemmet skyddar cellerna i slemhinnan från skadliga ämnen och mikroorganismer genom att ‘fånga’ dem och därmed hindra dem från att nå fram till cellerna. Slemmet är uppbyggt av stora, trådlika och ’klistriga’ molekyler, så kallade muciner, som gHighly glycosylated glycoproteins – mucins – are the major constituents of the mucus layer and glycocalyx that cover mucosal surfaces. Twelve human mucin genes have been identified, and the mucins may be divided into those that are membraneassociated and those that are secreted. Among the latter, the oligomeric mucins are responsible for mucus formation. The various tissues have characteristic muc

Genetic factors in childhood cancer. Associations between tumors in childhood and adulthood, and prevalence of germline TP53 mutations

The etiology of childhood cancer is largely unknown. Approximately 1-10% of all childhood tumors are associated with known cancer predisposition syndromes. However, the contribution may be underestimated due to the failure to detect patients with genetic susceptibility for cancer when relying on known family pattern and anomalies. Growing evidence indicates that patients with genetic susceptibilit

MANAGING DRUG USE IN THE ELDERLY. General practitioners’ adherence to guidelines and patients’ conceptions of medication

Introduction: Older patients’ knowledge about their medicines is generally poor. Patients are entitled to be informed on an individual and adequate level. Evidence-based guidelines should, in most cases, be followed also in the treatment of elderly to avoid suboptimal treatment, for example for cardiovascular conditions, or risky prescriptions in the case of renal impairment. Objectives: 1. To de

Miniaturised Bioanalytical Chemistry in Acoustically Levitated Droplets

Popular Abstract in Swedish Analytisk kemi är den gren inom kemin där man studerar, utvecklar och använder metoder och tekniker för att undersöka olika ämnens kemiska innehåll och exakta sammansättning. Den analytiska kemin spelar en mycket central roll inom många vitt skilda vetenskapliga fält och utgör den grund på vilka alla kemiska analyser vilar – medicinska tester och studier, kvalitetskontrFuelled by the current demands of the biological sciences, there is today a growing interest in microscale analysis. Miniaturisation of analytical instruments has become a long-standing trend. Miniaturisation offers several advantages, including rapid separation times, high performance and throughput, reduced costs, etc. But the increased surface area to volume ratio can sometimes be a disadvantag

Prognostic factors in squamous cell carcinoma of the head and neck, with emphasis on 11q13 rearrangements and cyclin D1 overexpression.

Popular Abstract in Swedish Populärvetenskaplig sammanfattning Skivepitelcancer i huvud- och halsregionen (SCCHN) Kliniska aspekter Prognosen vid SCCHN är i stort sett oförändrat dålig sedan 30 år tillbaka; cirka hälften av patienterna dör av sin sjukdom. Trots stora tekniska framsteg kring behandlingsteknikerna (ofta en kombination av kirurgi, strål- och i viss mån cellgiftsbehandling) medför dAt present, clinical outcome or response to therapy can not be fully predicted in individual cases of squamous cell carcinoma of the head and neck (SCCHN). The overall aim of the present studies was to investigate potential prognostic factors, more closely related to the malignant progression of a tumor than the established markers, such as the TNM-classification system. Tumor samples were investi

Publication in j neurochem

REV_ISS_WEB_jnc_6650_113-4 836..847 *MRC Clinical Sciences Centre, Faculty of Medicine, Imperial College, London, UK Wallenberg Neuroscience Centre, Lund University, Lund, Sweden The midbrain dopaminergic (mDA) neurons are the largest assembly of dopaminergic neurons in the central nervous system and play an important role in motor control, reward, addiction and cognition (Bjorklund and Lindvall 1

https://www.regenerative-neurobiology.lu.se/sites/regenerative-neurobiology.lu.se/files/publication_in_j_neurochem.pdf - 2026-05-27

IAC report 2024 WEBPAGE

Untitled ANNUAL REPORT  INTER ARTS CENTER | FACULTY OF FINE AND PERFORMING ARTS Contents 1 | Welcome ......................................................................................................................... 3 2 | About .............................................................................................................................. 4 3 | Brief facts ................

https://www.iac.lu.se/sites/iac.lu.se/files/2025-04/IAC_report_2024_WEBPAGE.pdf - 2026-05-27

Mven17 schema vt17 v.1

MVEN17 Samhällsplanering med klimatperspektiv Kurstid: 16 jan-17 mars 2017 Kursansvarig: Johanna Alkan Olsson johanna.alkan_olsson@cec.lu.se Lärare LU: Helena Hanson Helena.hanson@cec.lu.se Bengt Johansson bengt.johansson@miljo.lth.se Nora Smedby nora.smedby@iiiee.lu.se Kristoffer Mattisson kristoffer.mattisson@med.lu.se Jasmine Livingston jasmine.livingstone@cec.lu.se Terese Göransson terese.gora

https://www.cec.lu.se/sv/sites/cec.lu.se.sv/files/mven17_schema_vt17_v.1.pdf - 2026-05-27

Brevmall

Brevmall Postadress Box 117, 221 00 LUND Besöksadress Sölvegatan 14 A, LUND Telefon dir 046-222 4403, växel 046-222 00 00 Fax 046-222 4410 E-post isabella.grujoska@kansliht.lu.se Webbadress http://www.ht.lu.se Fakul te tss tyre lsen Humanistiska och teologiska fakulteternas plan för jämställdhet, likabehandling och mångfald 2014 Förutsättningar Arbetet med jämställdhet, likabehandling och mångfald

https://www.ctr.lu.se/fileadmin/user_upload/ctr/pdf/policy/JLM-plan_2014_BESLUT.pdf - 2026-05-25

Surgical management of cytologically indeterminate thyroid nodules

Nodules in the thyroid are frequent. Preoperative investigations including fine-needle cytology and ultrasound cannot in all patients rule out malignancy. Thus, surgical excision for histopathologic examination is often needed. In this narrative review, we examine aspects of the surgical management of indeterminate thyroid nodules, using a comprehensive review of the available literature. The auth

Enzymatic Reduction of Ketones

Methods have been studied for the production of chiral alcohols, which are of importance in organic synthesis of pharmaceuticals, agro-chemicals and fragrances, etc., through the enzymatic or microbial reduction of ketones. Classical reaction engineering was combined with genetic engineering to improve the production of chiral alcohols and kinetic resolution of racemic ketones with high enantiomer

The Ordovician System of South Africa : a review

Outcrops of the Ordovician System in South Africa are extensive; they cover significant portions of the Northern, Western and Eastern Cape provinces as part of the Cape Fold Belt as well as the KwaZulu-Natal Province as supracrustal cover overlying the Natal sector of the Paleoproterozoic Namaqua-Natal metamorphic province. Within the Cape Fold Belt, Ordovician rocks of the Table Mountain Group (P

Oxidation of 5-hydroxymethylfurfural with a novel aryl alcohol oxidase from Mycobacterium sp. MS1601

Bio-based 5-hydroxymethylfurfural (HMF) serves as an important platform for several chemicals, among which 2,5-furan dicarboxylic acid (FDCA) has attracted considerable interest as a monomer for the production of polyethylene furanoate (PEF), a potential alternative for fossil-based polyethylene terephthalate (PET). This study is based on the HMF oxidizing activity shown by Mycobacterium sp. MS 16

Choice of Indoor Standard in Hygrothermal Simulations of External Walls – Three Swedish Case Studies

When assessing the moisture damage risks of different external wall designs using hygrothermal simulation software, the user of said software can choose between different inputs for the determination of the indoor climate. This paper aims to compare results from field measurements in three Swedish buildings using different standards available in a widely used commercial hygrothermal simulation sof

Geophysical Investigation of a Rural Water Point Installation Program in Nampula Province, Mozambique

There are many projects in Mozambique for poverty reduction. One of these projects is funded by Millennium Challenge Account (MCA) and is aimed to install a total of 600 rural water points in the province of Nampula and Cabo Delgado in crystalline rock zone. Each water point consists of a drilled well, a water pump and a communal washing basin. Vertical Electrical Sounding (VES) was used for asse

Separating the chance effect from other diversity effects in the functioning of plant communities

The effect of plant species diversity on productivity and competitive ability was studied in an experiment carried out simultaneously in five European countries: Czech Republic (CZ), the Netherlands (NL), Sweden (SE), Spain (SP), and United Kingdom (UK). The aim was to separate the 'chance' or 'sampling effect' (increasing the number of sown species increases the probability that a species able 't