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The active site of sulfite reductase (SiR) consists of an unusual siroheme–Fe4S4 assembly coupled via a cysteinate sulfur, and serves for multi-electron reduction reactions. Clear explanations have not been demonstrated for the reasons behind the choice of siroheme (vs. other types of heme) or for the single-atom coupling to an Fe4S4 center (as opposed to simple adjacency or to coupling via chains

There are many projects in Mozambique for poverty reduction. One of these projects is funded by Millennium Challenge Account (MCA) and is aimed to install a total of 600 rural water points in the province of Nampula and Cabo Delgado in crystalline rock zone. Each water point consists of a drilled well, a water pump and a communal washing basin. Vertical Electrical Sounding (VES) was used for asses

Reliable information on solar activity over the Holocene period is important to predict the Sun in the future and to understand the mechanism behind the Sun-climate linkage. Presently, there are discrepancies in the proxy data of solar activity due to reasons that are not yet understood. This leads to major uncertainties in Holocene solar reconstructions. This PhD project aims to improve the Holoc

INTRODUCTION: Merkel cell carcinoma is a rare malignant cutaneous neoplasm that is locally invasive and frequently metastasizes to lymph nodes, liver, lungs, bone and brain. The incidence of Merkel cell carcinoma has increased in the past three decades.CASE PRESENTATION: A 65-year-old Caucasian man presented with a sudden onset of severe headache and a three-month history of balance disturbance. M

Vad spelar Arktis för roll i klimatförändringarna? Denna avlägsna, och glest befolkade, del av världen utgör faktiskt en viktig del av klimatsystemet. Arktis spelar en betydande roll i kolets kretslopp; vilket innefattar såväl koldioxid och metan, två av de viktigaste växthusgaserna. Förändringar i koncentrationer av växthusgaser påverkar hur mycket värme som hålls kvar i jordens atmosfär. VåtmarkMethane is one of the most important greenhouse gases, and the Arctic region plays an important role in its dynamics. Due to limited observations in this remote and often harsh environments, large uncertainties surround the role of the Arctic region in a warming climate. In this thesis, I examine the performance of the three low-cost solid state sensors, Figaro sensors TGS2600-B00, TGS2611-C00 an

Privata skogsägares syn på att bevara natur vid installation av vind-kraft i skog De svenska skogarna är stora, nästan 80 procent av Sveriges yta är täckt av skog. Det låter mycket, men skogen har många användningsområden. Den ger oss virke och papper, möj-ligheter till vandring och turism, plats för vindkraft och är hem åt djur och växter. Samtidigt minskar antalet arter på vår planet, och både kThis study aimed to gain a deeper understanding of Swedish small forest owners’ perspectives on ecological compensation on their land in relation to wind farm construction, specifically how their sense of ownership influences their willingness to engage in such activities. To fulfil this aim, semi-structured interviews were conducted with ten private forest owners who had signed agreements for win

Abstract To estimate the timescale of hepatitis B virus (HBV) evolutionary history and analyzing its phylogeographic patterns, publically available HBV sequences were collected from GenBank. Among those, 412 sequences were from genotype A and 566 sequences were from genotype D. These sequences comprised the entire genome and represented samples obtained between 1982 and 2009 from different parts

Links within the page Heads of the departmentThe head of the department holds the executive role and responsibility for the everyday operations of the department. The responsibilities and authority of the head of the department are regulated by the Faculty of Science’s delegation rules. According to the delegation rules, the head of the department shall manage and develop the department and is res

https://www.biology.lu.se/internal/organisation-and-contact - 2026-06-05

From the Management It was so good to see as many of you at the Staff Day last Friday! It was obvious that meeting and have a chat with new and old colleagues in real life was something we have missed for a long time. We learned a lot about each other and urban planning, and there were many nice words written down, you will hear them all being read out loud in the coming Friday fikas. Finally, a h

https://www.cec.lu.se/staff-pages/staff-newsletters/28-april-2022 - 2026-06-05

MVEN17 Samhällsplanering med klimatperspektiv Kurstid: 16 jan-17 mars 2017 Kursansvarig: Johanna Alkan Olsson johanna.alkan_olsson@cec.lu.se Lärare LU: Helena Hanson Helena.hanson@cec.lu.se Bengt Johansson bengt.johansson@miljo.lth.se Nora Smedby nora.smedby@iiiee.lu.se Kristoffer Mattisson kristoffer.mattisson@med.lu.se Jasmine Livingston jasmine.livingstone@cec.lu.se Terese Göransson terese.gora

https://www.cec.lu.se/sv/sites/cec.lu.se.sv/files/mven17_schema_vt17_v.1.pdf - 2026-06-06

Progamme evaluation of PhD education in Service Studies: Statement from external expert group Page 1 of 23 STATEMENT FROM EXTERNAL EXPERT GROUP Reg. No. STYR 2023/22 2023-11-03 Evaluation report for the Department of Human Geography: bachelor and master studies in Human Geography and Urban planning Assignment and composition of the external expert group The expert group consists of two (originally

https://www.sam.lu.se/internt/sites/sam.lu.se.internt/files/2024-05/Statement-expert-group_HUGE_final.pdf - 2026-06-06

Pancreatic cancer is the fourth cause of cancer-related death with a 5-year survival rate less than 5%. Two of the risk factors are chronic pancreatitis and type 2 diabetes (T2D), which are believed to promote the tumour progression. Pancreatic cancer and its tumour microenvironment is characterised by a dense stroma, immune cell infiltration and poor vascularisation. This creates a favourable env

Popular Abstract in Swedish Pyrimidiner är DNA-byggstenar som är essentiella för cellens överlevnad och delning. I mänskliga celler finns pyrimidiner att tillgå antingen genom återupptag eller genom biosyntes (nysyntes). Biosyntesen av pyrimidiner sker i flera steg och i ett av dem spelar enzymet Dihydroorotat dehydrogenas (DHODH) en avgörande roll genom att katalysera en oxidationsreaktion. När cIn the first part of the PhD work, small chemical entities (fragments) found to inhibit human dihydroorotate dehydrogenase (DHODH), were chemically optimized. As part of an ample program at Active Biotech to find new drugs against autoimmune diseases, expanded fragments were repeatedly designed, synthesized and evaluated in a human DHODH assay. Potent inhibitors were identified within three classe

Popular Abstract in Swedish Den kroniska inflammation som ses hos personer med inflammatorisk tarmsjukdom är troligen en immunologisk reaktion riktad mot normala tarmbakterier. I denna process har monocyter/makrofager (särskild celltyp av vita blodkroppar) en central betydelse. Det är huvudsakligen makrofager i tarmslemhinnan som styr det immunsvar som utvecklas då tarmfloran kommer i kontakt med Inflammatory bowel disease is thought to result from the inappropriate and ongoing activation of the mucosal immune system driven by the presence of normal luminal flora. In this process monocytes/macrophages contribute to and maintain chronic inflammation by being both regulatory and effector cells. This study aimed at exploring the effects and regulation of chronic inflammation in inflammatory

Popular Abstract in Swedish p53 Ñett protein som kan fŒ leukemiceller att bli mera mogna Vid akut leukemi ansamlas omogna blodceller med nedsatt fšrmŒga till utmognad och programmerad celldšd. Detta leder till frŒnvaro av normala blodceller, vilket Šr huvudorsaken till de infektioner och blšdningsrubbningar som utgšr leukemins frŠmsta symptom. Akut leukemi har hittills framfšr allt behandlats medThe terminal differentiation of leukemic cells is closely connected to their death. The concept of differentiation therapy originates from the idea that forced maturation of leukemic cells could induce cell death without the side-effects that are provoked by ordinary chemotherapy. The tumour suppressor protein p53 is a transcription factor, and can induce cell cycle arrest and apoptosis of maligna

Popular Abstract in Swedish Frontotemporal demens är ett sjukdomstillstånd där nervceller i hjärnans pann- (“fronto”) och tinninglober (“temporal”) förtvinar, vilket leder till en tilltagande cellförlust och uttunning av hjärnbarken i dessa områden. Till skillnad från Alzheimers sjukdom, den vanligaste demenssjukdomen, leder frontotemporal demens i första hand inte till försämrat minne och orienteThe present thesis explores alterations in brain morphology in the neurodegenerative disorder of frontotemporal dementia (FTD). With the aim to improve the clinical diagnostics of FTD, we explored the diagnostic potential of measuring morphological alterations in the white matter by diffusion tensor imaging (DTI)- MRI, compared with the more commonly used assessment of grey matter thickness and vo

Background: There are differences in drug use depending on non-medical factors such as age, gender and socioeconomic status. The combined effect of these factors, with adjustment for multimorbidity, is highly relevant to study to ensure equality in drug use. Objectives: 1. To examine drug use related to age, gender, income and education after adjustment for multimorbidity, in an entire adult popul

Popular Abstract in Swedish Immunförsvaret har till uppgift att skydda kroppen mot främmande mikroorganismer såsom bakterier och virus. En rad olika celler, vävnader samt organ samarbetar för att utforma ett väl fungerande immunförsvar. Det är ytterst viktigt att immunförsvaret känner igen kroppsfrämmande ämnen (antigen), som till exempel bakterieceller, men också att det skiljer dessa från kroppsGeneration of long-lived plasma cells and memory B cells of high affinity takes place in germinal centers and depends on help from a specialized CD4+ T cell subset termed T follicular helper (Tfh) cells. These processes are crucial for long-term protection upon natural infection or in settings of vaccination, however they are also responsible for development of antibody-mediated autoimmune disease

Popular Abstract in Swedish Blodet har en viktig funktion i kroppen. Blodet bildas i den röda benmärgen och består av olika typer av celler med olika specialiserade funktioner, varav många livsnödvändiga. De röda blodkropparna transporterar syre till alla våra kroppsdelar så att våra muskler fungerar och vi orkar gå och springa och så att vår hjärna kan arbeta. De vita blodkropparna hjälper oss atThe t(6;9) translocation is found in a subset of patients with acute myeloid leukemia (AML) and is associated with a poor prognosis. The translocation results in the formation of the DEK-NUP214 fusion protein containing almost the entire nuclear protein DEK and two thirds of the nucleoporin NUP214. The molecular mechanisms behind the leukemic conversion of cells expressing the fusion protein DEK-N

Chatbots are increasingly being adapted as substitutes to humans in customer service. As the level of adoption increases, it becomes more important to understand the phenomenon of robots replacing humans – a new chapter in the rising digital world. Earlier research has explored and aroused criticism against the trend of automation and digitalization, urging companies to move towards a more customeAbstract Title: ”Is this what you mean? – No, it really isn't!” – An analysis of consumers' dissatisfaction in encounters with chatbots in customer service Seminar date: January 10th, 2024 Course: FEKH29, Business Administration: Bachelor Degree Project in Marketing Undergraduate Level, 15 ECTS-credits Authors: Emma Axelsson, Annie Bolmgren and Julia Krusell Advisor: Sofia Ulver Keywords: